| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | 1,458,333 | 2,291,666 | +833,333 | 0.33 | 0.84 | +0.51 | buy |
| MARSHALL WACE, LLP | 0 | 31,211 | +31,211 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 0 | 10,179 | +10,179 | 0.00 | 0.00 | +0.00 | buy |
| VSM Wealth Advisory, LLC | 4,000 | 9,000 | +5,000 | 0.01 | 0.03 | +0.03 | buy |
| GAMMA Investing LLC | 1,380 | 2,117 | +737 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 0 | 196 | +196 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 51 | 218 | +167 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 93 | 100 | +7 | 0.00 | 0.00 | +0.00 | buy |
| IRONWOOD INVESTMENT MANAGEMENT LLC | 25,135 | 25,135 | 0 | 0.07 | 0.13 | +0.06 | hold |
| Allworth Financial LP | 7 | 7 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Activest Wealth Management | 1 | 1 | 0 | 0.00 | 0.00 | +0.00 | hold |
| GENERAL AMERICAN INVESTORS CO INC | 354,361 | 354,361 | 0 | 0.13 | 0.27 | +0.14 | hold |
| Ridgewood Investments LLC | 550 | 0 | -550 | 0.00 | 0.00 | -0.00 | sell |
| Marex Group plc | 11,300 | 0 | -11,300 | 0.00 | 0.00 | -0.00 | sell |
| Novo Holdings A/S | 2,375,000 | 2,345,000 | -30,000 | 0.95 | 1.84 | +0.89 | sell |
| CITADEL ADVISORS LLC | 35,738 | 0 | -35,738 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 245,177 | 153,990 | -91,187 | 0.00 | 0.00 | +0.00 | sell |