| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| XTX Topco Ltd | 0 | 10,634 | +10,634 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 0 | 5,000 | +5,000 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 218 | 1,763 | +1,545 | 0.00 | 0.00 | +0.00 | buy |
| Clearstead Advisors, LLC | 0 | 48 | +48 | 0.00 | 0.00 | +0.00 | buy |
| Smartleaf Asset Management LLC | 0 | 43 | +43 | 0.00 | 0.00 | +0.00 | buy |
| IRONWOOD INVESTMENT MANAGEMENT LLC | 25,135 | 25,135 | 0 | 0.13 | 0.09 | -0.04 | hold |
| Allworth Financial LP | 7 | 7 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Activest Wealth Management | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Frazier Life Sciences Management, L.P. | 2,291,666 | 2,291,666 | 0 | 0.84 | 0.54 | -0.29 | hold |
| GENERAL AMERICAN INVESTORS CO INC | 354,361 | 354,361 | 0 | 0.27 | 0.19 | -0.08 | hold |
| EverSource Wealth Advisors, LLC | 100 | 98 | -2 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 196 | 0 | -196 | 0.00 | 0.00 | -0.00 | sell |
| GAMMA Investing LLC | 2,117 | 1,857 | -260 | 0.00 | 0.00 | -0.00 | sell |
| VSM Wealth Advisory, LLC | 9,000 | 0 | -9,000 | 0.03 | 0.00 | -0.03 | sell |
| JPMORGAN CHASE & CO | 10,179 | 0 | -10,179 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 153,990 | 123,463 | -30,527 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 31,211 | 0 | -31,211 | 0.00 | 0.00 | -0.00 | sell |
| Novo Holdings A/S | 2,345,000 | 2,305,000 | -40,000 | 1.84 | 1.58 | -0.27 | sell |