| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 902,531 | 1,135,716 | +233,185 | 0.00 | 0.00 | -0.00 | buy |
| Avantax Planning Partners, Inc. | 0 | 150,399 | +150,399 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 10,824 | 84,068 | +73,244 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 51,110 | +51,110 | 0.00 | 0.00 | +0.00 | buy |
| Scientech Research LLC | 0 | 42,546 | +42,546 | 0.00 | 0.01 | +0.01 | buy |
| ADAR1 Capital Management, LLC | 0 | 40,000 | +40,000 | 0.00 | 0.01 | +0.01 | buy |
| NORTHERN TRUST CORP | 39,208 | 66,609 | +27,401 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 358,422 | 379,016 | +20,594 | 0.00 | 0.00 | -0.00 | buy |
| Dunhill Financial, LLC | 0 | 10,274 | +10,274 | 0.00 | 0.00 | +0.00 | buy |
| INVESTORS ASSET MANAGEMENT OF GEORGIA INC /GA/ /ADV | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| Aptus Capital Advisors, LLC | 41,000 | 46,000 | +5,000 | 0.00 | 0.00 | -0.00 | buy |
| SevenBridge Financial Group, LLC | 41,000 | 46,000 | +5,000 | 0.01 | 0.01 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 71,081 | 71,081 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Mariner, LLC | 25,000 | 25,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TAKEDA PHARMACEUTICAL CO LTD | 1,475,121 | 1,475,121 | 0 | 5.33 | 6.59 | +1.26 | hold |
| Trustees of Columbia University in the City of New York | 249,635 | 249,635 | 0 | 0.04 | 0.03 | -0.01 | hold |
| Bain Capital Life Sciences Investors, LLC | 4,566,817 | 4,566,817 | 0 | 0.51 | 0.49 | -0.02 | hold |
| AJU IB Investment Co., Ltd. | 667,742 | 667,742 | 0 | 0.62 | 0.58 | -0.05 | hold |
| Steward Partners Investment Advisory, LLC | 20,000 | 20,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Key FInancial Inc | 830 | 830 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Pinnacle Financial Group, LLC / IL | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Private Wealth Management Group, LLC | 310 | 310 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Federation des caisses Desjardins du Quebec | 3,300 | 3,300 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Merck & Co., Inc. | 1,483,758 | 1,483,758 | 0 | 0.55 | 0.65 | +0.11 | hold |
| GILEAD SCIENCES, INC. | 9,105,451 | 9,105,451 | 0 | 0.56 | 0.56 | -0.00 | hold |
| STATE STREET CORP | 43,390 | 43,390 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BlackRock, Inc. | 76,086 | 74,700 | -1,386 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 2,729 | 0 | -2,729 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 12,870 | 0 | -12,870 | 0.00 | 0.00 | -0.00 | sell |
| RAYMOND JAMES FINANCIAL INC | 50,086 | 33,961 | -16,125 | 0.00 | 0.00 | -0.00 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 343,230 | 254,346 | -88,884 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 296,617 | 177,700 | -118,917 | 0.00 | 0.00 | -0.00 | sell |
| FIL Ltd | 218,705 | 0 | -218,705 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 1,395,853 | 884,035 | -511,818 | 0.00 | 0.00 | -0.00 | sell |
| Rock Springs Capital Management LP | 3,003,259 | 0 | -3,003,259 | 0.11 | 0.00 | -0.11 | sell |