| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Bain Capital Life Sciences Investors, LLC | 3,785,450 | 4,566,817 | +781,367 | 0.39 | 0.37 | -0.02 | buy |
| MORGAN STANLEY | 1,112,740 | 1,522,102 | +409,362 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 182,855 | 338,192 | +155,337 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 32,752 | +32,752 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA SECURITIES, LLC | 13,271 | 44,445 | +31,174 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 0 | 25,317 | +25,317 | 0.00 | 0.00 | +0.00 | buy |
| Steward Partners Investment Advisory, LLC | 0 | 20,000 | +20,000 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 10,389 | +10,389 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 12,205 | 20,655 | +8,450 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 4,207 | 5,616 | +1,409 | 0.00 | 0.00 | +0.00 | buy |
| Private Wealth Management Group, LLC | 0 | 310 | +310 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 902,531 | 902,531 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 71,081 | 71,081 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BALYASNY ASSET MANAGEMENT L.P. | 272,486 | 272,486 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TAKEDA PHARMACEUTICAL CO LTD | 1,475,121 | 1,475,121 | 0 | 0.60 | 3.06 | +2.46 | hold |
| Rock Springs Capital Management LP | 3,003,259 | 3,003,259 | 0 | 0.09 | 0.08 | -0.01 | hold |
| SevenBridge Financial Group, LLC | 41,000 | 41,000 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Key FInancial Inc | 830 | 830 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Pinnacle Financial Group, LLC / IL | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Dunhill Financial, LLC | 10,274 | 10,274 | 0 | 0.01 | 0.00 | -0.00 | hold |
| FMR LLC | 1,395,853 | 1,395,853 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FIL Ltd | 218,705 | 218,705 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NORTHERN TRUST CORP | 39,208 | 39,208 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 43,390 | 43,390 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Qube Research & Technologies Ltd | 4 | 0 | -4 | 0.00 | 0.00 | -0.00 | sell |
| ADAR1 Capital Management, LLC | 1,500 | 0 | -1,500 | 0.00 | 0.00 | -0.00 | sell |
| Avantax Planning Partners, Inc. | 25,000 | 20,483 | -4,517 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 33,289 | 23,862 | -9,427 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 11,925 | 0 | -11,925 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 295,000 | 266,300 | -28,700 | 0.00 | 0.00 | -0.00 | sell |