| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BALYASNY ASSET MANAGEMENT L.P. | 272,486 | 343,230 | +70,744 | 0.00 | 0.00 | +0.00 | buy |
| Aptus Capital Advisors, LLC | 0 | 41,000 | +41,000 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 266,300 | 296,617 | +30,317 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 338,192 | 358,422 | +20,230 | 0.00 | 0.00 | +0.00 | buy |
| Federation des caisses Desjardins du Quebec | 0 | 3,300 | +3,300 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 75,624 | 76,086 | +462 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 10,389 | 10,824 | +435 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 902,531 | 902,531 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 71,081 | 71,081 | 0 | 0.00 | 0.00 | +0.00 | hold |
| TAKEDA PHARMACEUTICAL CO LTD | 1,475,121 | 1,475,121 | 0 | 3.06 | 5.33 | +2.27 | hold |
| Trustees of Columbia University in the City of New York | 249,635 | 249,635 | 0 | 0.29 | 0.04 | -0.25 | hold |
| Rock Springs Capital Management LP | 3,003,259 | 3,003,259 | 0 | 0.08 | 0.11 | +0.03 | hold |
| SevenBridge Financial Group, LLC | 41,000 | 41,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Bain Capital Life Sciences Investors, LLC | 4,566,817 | 4,566,817 | 0 | 0.37 | 0.51 | +0.14 | hold |
| Steward Partners Investment Advisory, LLC | 20,000 | 20,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Key FInancial Inc | 830 | 830 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Pinnacle Financial Group, LLC / IL | 10,000 | 10,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Private Wealth Management Group, LLC | 310 | 310 | 0 | 0.00 | 0.00 | +0.00 | hold |
| FMR LLC | 1,395,853 | 1,395,853 | 0 | 0.00 | 0.00 | +0.00 | hold |
| FIL Ltd | 218,705 | 218,705 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NORTHERN TRUST CORP | 39,208 | 39,208 | 0 | 0.00 | 0.00 | +0.00 | hold |
| STATE STREET CORP | 43,390 | 43,390 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Mariner, LLC | 25,317 | 25,000 | -317 | 0.00 | 0.00 | +0.00 | sell |
| Tower Research Capital LLC (TRC) | 5,616 | 2,729 | -2,887 | 0.00 | 0.00 | -0.00 | sell |
| Dunhill Financial, LLC | 10,274 | 0 | -10,274 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 23,862 | 12,870 | -10,992 | 0.00 | 0.00 | -0.00 | sell |
| Avantax Planning Partners, Inc. | 20,483 | 0 | -20,483 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 20,655 | 0 | -20,655 | 0.00 | 0.00 | -0.00 | sell |
| Engineers Gate Manager LP | 32,752 | 0 | -32,752 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA SECURITIES, LLC | 44,445 | 0 | -44,445 | 0.00 | 0.00 | -0.00 | sell |
| MORGAN STANLEY | 1,522,102 | 0 | -1,522,102 | 0.00 | 0.00 | -0.00 | sell |