| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Blue Owl Capital Holdings LP | 6,357,928 | 7,367,906 | +1,009,978 | 1.54 | 1.45 | -0.08 | buy |
| Shay Capital LLC | 50,000 | 189,853 | +139,853 | 0.01 | 0.03 | +0.02 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 338,435 | 425,500 | +87,065 | 0.00 | 0.00 | -0.00 | buy |
| XTX Topco Ltd | 0 | 15,673 | +15,673 | 0.00 | 0.00 | +0.00 | buy |
| CW Advisors, LLC | 0 | 15,000 | +15,000 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 13,304 | +13,304 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 628,729 | 639,219 | +10,490 | 0.00 | 0.00 | -0.00 | buy |
| Walleye Capital LLC | 166,306 | 168,960 | +2,654 | 0.00 | 0.00 | -0.00 | buy |
| Banque Transatlantique SA | 0 | 1,800 | +1,800 | 0.00 | 0.00 | +0.00 | buy |
| GREAT POINT PARTNERS LLC | 4,683,711 | 4,683,711 | 0 | 2.32 | 1.56 | -0.76 | hold |
| CAXTON CORP | 18,403 | 18,403 | 0 | 0.12 | 0.22 | +0.11 | hold |
| Blackstone Inc. | 2,440,330 | 2,440,330 | 0 | 0.01 | 0.01 | -0.01 | hold |
| Alyeska Investment Group, L.P. | 1,663,355 | 1,663,355 | 0 | 0.01 | 0.00 | -0.00 | hold |
| HighTower Advisors, LLC | 125,852 | 125,852 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Nantahala Capital Management, LLC | 1,935,484 | 1,935,484 | 0 | 0.14 | 0.10 | -0.04 | hold |
| Sio Capital Management, LLC | 1,328,352 | 1,328,352 | 0 | 0.39 | 0.25 | -0.15 | hold |
| Clear Harbor Asset Management, LLC | 57,804 | 57,804 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Cerity Partners LLC | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MPM BioImpact LLC | 14,705,882 | 14,705,882 | 0 | 2.19 | 1.55 | -0.64 | hold |
| Avidity Partners Management LP | 7,477,200 | 7,477,200 | 0 | 0.78 | 0.94 | +0.16 | hold |
| Velan Capital Investment Management LP | 90,000 | 90,000 | 0 | 0.08 | 0.06 | -0.02 | hold |
| SBI Securities Co., Ltd. | 113 | 113 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Deep Track Capital, LP | 7,419,355 | 7,419,355 | 0 | 0.29 | 0.15 | -0.15 | hold |
| ADAR1 Capital Management, LLC | 351,094 | 351,094 | 0 | 0.08 | 0.04 | -0.03 | hold |
| Allostery Investments LP | 950,166 | 950,166 | 0 | 1.96 | 0.84 | -1.12 | hold |
| FRANKLIN RESOURCES INC | 4,003,380 | 4,003,380 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NORTHERN TRUST CORP | 113,565 | 113,565 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| STATE STREET CORP | 152,607 | 152,607 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Woodline Partners LP | 1,361,350 | 1,361,188 | -162 | 0.01 | 0.01 | -0.00 | sell |
| VANGUARD GROUP INC | 3,255,463 | 3,253,467 | -1,996 | 0.00 | 0.00 | -0.00 | sell |
| United Capital Management of KS, Inc. | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| Virtu Financial LLC | 11,638 | 0 | -11,638 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 16,668 | 0 | -16,668 | 0.00 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 22,710 | 0 | -22,710 | 0.00 | 0.00 | -0.00 | sell |
| GSA CAPITAL PARTNERS LLP | 27,122 | 0 | -27,122 | 0.00 | 0.00 | -0.00 | sell |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 90,000 | 41,216 | -48,784 | 0.01 | 0.00 | -0.01 | sell |
| Aster Capital Management (DIFC) Ltd | 52,792 | 0 | -52,792 | 0.02 | 0.00 | -0.02 | sell |
| CITIGROUP INC | 54,454 | 0 | -54,454 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 912,405 | 848,970 | -63,435 | 0.00 | 0.00 | -0.00 | sell |
| Mill Creek Capital Advisors, LLC | 104,631 | 0 | -104,631 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 178,718 | 48,671 | -130,047 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 322,838 | 174,309 | -148,529 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 203,286 | 0 | -203,286 | 0.00 | 0.00 | -0.00 | sell |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 308,758 | 67,631 | -241,127 | 0.01 | 0.00 | -0.01 | sell |
| Affinity Asset Advisors, LLC | 1,015,340 | 660,589 | -354,751 | 0.17 | 0.06 | -0.10 | sell |
| Ally Bridge Group (NY) LLC | 1,576,762 | 1,157,448 | -419,314 | 1.42 | 0.64 | -0.78 | sell |
| UBS Group AG | 699,129 | 0 | -699,129 | 0.00 | 0.00 | -0.00 | sell |