| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| GREAT POINT PARTNERS LLC | 0 | 7,419,355 | +7,419,355 | 0.00 | 2.85 | +2.85 | buy |
| Avidity Partners Management LP | 0 | 7,419,355 | +7,419,355 | 0.00 | 0.63 | +0.63 | buy |
| Deep Track Capital, LP | 0 | 7,419,355 | +7,419,355 | 0.00 | 0.44 | +0.44 | buy |
| Blue Owl Capital Holdings LP | 0 | 5,161,290 | +5,161,290 | 0.00 | 2.88 | +2.88 | buy |
| VANGUARD GROUP INC | 598,303 | 4,502,198 | +3,903,895 | 0.00 | 0.00 | +0.00 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 0 | 2,258,065 | +2,258,065 | 0.00 | 0.04 | +0.04 | buy |
| Alyeska Investment Group, L.P. | 0 | 1,935,484 | +1,935,484 | 0.00 | 0.02 | +0.02 | buy |
| Nantahala Capital Management, LLC | 0 | 1,935,484 | +1,935,484 | 0.00 | 0.39 | +0.39 | buy |
| Blackstone Inc. | 0 | 1,838,709 | +1,838,709 | 0.00 | 0.02 | +0.02 | buy |
| Sio Capital Management, LLC | 0 | 1,328,352 | +1,328,352 | 0.00 | 1.00 | +1.00 | buy |
| Affinity Asset Advisors, LLC | 328,817 | 1,619,140 | +1,290,323 | 0.07 | 0.51 | +0.44 | buy |
| Velan Capital Investment Management LP | 0 | 1,290,323 | +1,290,323 | 0.00 | 1.48 | +1.48 | buy |
| Ally Bridge Group (NY) LLC | 725,951 | 1,886,232 | +1,160,281 | 0.56 | 2.25 | +1.70 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 101,072 | 618,174 | +517,102 | 0.00 | 0.00 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 205,934 | 645,161 | +439,227 | 0.08 | 0.26 | +0.18 | buy |
| Altium Capital Management LLC | 0 | 360,001 | +360,001 | 0.00 | 0.30 | +0.30 | buy |
| NORTHERN TRUST CORP | 37,219 | 174,497 | +137,278 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 0 | 108,376 | +108,376 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 32,907 | 92,107 | +59,200 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 39,900 | 65,200 | +25,300 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 24,750 | +24,750 | 0.00 | 0.00 | +0.00 | buy |
| CAXTON CORP | 0 | 18,403 | +18,403 | 0.00 | 0.19 | +0.19 | buy |
| Verition Fund Management LLC | 0 | 16,294 | +16,294 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 13,844 | +13,844 | 0.00 | 0.00 | +0.00 | buy |
| HighTower Advisors, LLC | 125,852 | 125,852 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Clear Harbor Asset Management, LLC | 36,000 | 36,000 | 0 | 0.00 | 0.01 | +0.00 | hold |
| Mill Creek Capital Advisors, LLC | 104,631 | 104,631 | 0 | 0.00 | 0.01 | +0.00 | hold |
| Federation des caisses Desjardins du Quebec | 400 | 400 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 296,675 | 293,758 | -2,917 | 0.01 | 0.02 | +0.00 | sell |
| Tower Research Capital LLC (TRC) | 6,357 | 0 | -6,357 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 10,261 | 0 | -10,261 | 0.00 | 0.00 | -0.00 | sell |
| Jefferies Financial Group Inc. | 11,453 | 0 | -11,453 | 0.00 | 0.00 | -0.00 | sell |
| SHEETS SMITH WEALTH MANAGEMENT | 20,000 | 0 | -20,000 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 105,809 | 41,469 | -64,340 | 0.00 | 0.00 | -0.00 | sell |
| Opaleye Management Inc. | 1,108,357 | 0 | -1,108,357 | 0.33 | 0.00 | -0.33 | sell |