| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Opaleye Management Inc. | 0 | 375,204 | +375,204 | 0.00 | 0.05 | +0.05 | buy |
| CHOREO, LLC | 0 | 33,255 | +33,255 | 0.00 | 0.00 | +0.00 | buy |
| Quantinno Capital Management LP | 0 | 33,255 | +33,255 | 0.00 | 0.00 | +0.00 | buy |
| Stonepine Capital Management, LLC | 850,000 | 862,996 | +12,996 | 1.20 | 0.99 | -0.22 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 11,200 | +11,200 | 0.00 | 0.00 | +0.00 | buy |
| Steward Partners Investment Advisory, LLC | 0 | 6,000 | +6,000 | 0.00 | 0.00 | +0.00 | buy |
| Woodline Partners LP | 3,652,190 | 3,652,768 | +578 | 0.02 | 0.02 | -0.01 | buy |
| XTX Topco Ltd | 37,652 | 37,769 | +117 | 0.00 | 0.00 | -0.00 | buy |
| Continuum Advisory, LLC | 0 | 50 | +50 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 0 | 3 | +3 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 12,090 | 12,090 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Cerity Partners LLC | 12,812 | 12,812 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Dauntless Investment Group, LLC | 3,819 | 0 | -3,819 | 0.02 | 0.00 | -0.02 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 584,796 | 580,596 | -4,200 | 0.00 | 0.00 | -0.00 | sell |
| Maven Securities LTD | 1,175,535 | 809,317 | -366,218 | 0.11 | 0.08 | -0.03 | sell |