| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ACADIAN ASSET MANAGEMENT LLC | 141,276 | 284,229 | +142,953 | 0.00 | 0.00 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 24,204 | 111,079 | +86,875 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 2,533,874 | 2,594,745 | +60,871 | 0.00 | 0.00 | -0.00 | buy |
| GOLDMAN SACHS GROUP INC | 141,583 | 179,635 | +38,052 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA ADVISERS, LP | 51,000 | 76,900 | +25,900 | 0.00 | 0.00 | -0.00 | buy |
| IEQ CAPITAL, LLC | 0 | 22,841 | +22,841 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 66,797 | 86,006 | +19,209 | 0.00 | 0.00 | -0.00 | buy |
| Cerity Partners LLC | 0 | 14,260 | +14,260 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 22,892 | 35,814 | +12,922 | 0.00 | 0.00 | -0.00 | buy |
| CIBC WORLD MARKETS CORP | 0 | 10,384 | +10,384 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 9,809 | 17,508 | +7,699 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 78,653 | 85,083 | +6,430 | 0.00 | 0.00 | -0.00 | buy |
| SG Americas Securities, LLC | 19,383 | 25,314 | +5,931 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 1,478 | 6,849 | +5,371 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 26,277 | 27,447 | +1,170 | 0.00 | 0.00 | -0.00 | buy |
| SBI Securities Co., Ltd. | 280 | 1,130 | +850 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 43,091 | 43,273 | +182 | 0.00 | 0.00 | -0.00 | buy |
| True Wealth Design, LLC | 0 | 55 | +55 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 41 | +41 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 905 | 905 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,324 | 3,324 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 20,020 | 20,020 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HARBOURVEST PARTNERS LLC | 29,018 | 29,018 | 0 | 0.01 | 0.01 | -0.01 | hold |
| TANG CAPITAL MANAGEMENT LLC | 900,000 | 900,000 | 0 | 0.06 | 0.02 | -0.04 | hold |
| DAFNA Capital Management LLC | 1,704,232 | 1,704,232 | 0 | 0.44 | 0.23 | -0.21 | hold |
| Bank of New York Mellon Corp | 105,529 | 105,529 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Parametrica Management Ltd | 27,840 | 27,840 | 0 | 0.04 | 0.02 | -0.01 | hold |
| MARK SHEPTOFF FINANCIAL PLANNING, LLC | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Bain Capital Life Sciences Investors, LLC | 5,410,361 | 5,410,361 | 0 | 0.64 | 0.38 | -0.26 | hold |
| Syncona Portfolio Ltd | 1,213,056 | 1,213,056 | 0 | 2.31 | 2.19 | -0.12 | hold |
| SUPERSTRING CAPITAL MANAGEMENT LP | 462,963 | 462,963 | 0 | 0.41 | 0.26 | -0.15 | hold |
| SEI INVESTMENTS CO | 52,748 | 52,748 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Legal & General Group Plc | 3,976 | 3,976 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PRICE T ROWE ASSOCIATES INC /MD/ | 14,882 | 14,882 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 13,743 | 13,743 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 706 | 706 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DIMENSIONAL FUND ADVISORS LP | 26,874 | 26,735 | -139 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 23,265 | 22,925 | -340 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 977 | 300 | -677 | 0.00 | 0.00 | -0.00 | sell |
| Sterling Capital Management LLC | 1,589 | 807 | -782 | 0.00 | 0.00 | -0.00 | sell |
| PANAGORA ASSET MANAGEMENT INC | 91,755 | 90,739 | -1,016 | 0.00 | 0.00 | -0.00 | sell |
| ProShare Advisors LLC | 13,180 | 10,131 | -3,049 | 0.00 | 0.00 | -0.00 | sell |
| CLEAR STREET LLC | 3,100 | 0 | -3,100 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 36,094 | 32,859 | -3,235 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 2,381,707 | 2,377,494 | -4,213 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 9,792 | 4,282 | -5,510 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 852,791 | 846,221 | -6,570 | 0.00 | 0.00 | -0.00 | sell |
| FOUNDERS FINANCIAL SECURITIES LLC | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| Vanguard Personalized Indexing Management, LLC | 10,214 | 0 | -10,214 | 0.00 | 0.00 | -0.00 | sell |
| PRUDENTIAL FINANCIAL INC | 15,150 | 0 | -15,150 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 1,202,885 | 1,185,318 | -17,567 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 3,037,248 | 3,018,515 | -18,733 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 991,595 | 970,260 | -21,335 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 70,475 | 47,209 | -23,266 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 164,871 | 132,929 | -31,942 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 35,511 | 0 | -35,511 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 85,993 | 43,514 | -42,479 | 0.01 | 0.00 | -0.01 | sell |
| NORTHERN TRUST CORP | 336,989 | 289,601 | -47,388 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 357,805 | 270,820 | -86,985 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 193,368 | 96,140 | -97,228 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 249,700 | 120,500 | -129,200 | 0.01 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 163,189 | 0 | -163,189 | 0.00 | 0.00 | -0.00 | sell |
| Index Venture Life Associates VI Ltd | 188,251 | 0 | -188,251 | 0.11 | 0.00 | -0.11 | sell |
| CITADEL ADVISORS LLC | 520,228 | 0 | -520,228 | 0.00 | 0.00 | -0.00 | sell |
| BAKER BROS. ADVISORS LP | 797,460 | 241,684 | -555,776 | 0.01 | 0.00 | -0.01 | sell |
| VR Adviser, LLC | 3,957,186 | 2,498,069 | -1,459,117 | 0.27 | 0.10 | -0.17 | sell |
| MILLENNIUM MANAGEMENT LLC | 1,607,174 | 0 | -1,607,174 | 0.00 | 0.00 | -0.00 | sell |
| Casdin Capital, LLC | 5,190,506 | 3,212,316 | -1,978,190 | 0.35 | 0.12 | -0.23 | sell |