| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RENAISSANCE TECHNOLOGIES LLC | 1,185,318 | 2,022,500 | +837,182 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 812,213 | +812,213 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 86,006 | 572,544 | +486,538 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 466,606 | +466,606 | 0.00 | 0.02 | +0.02 | buy |
| JANE STREET GROUP, LLC | 0 | 444,590 | +444,590 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 76,900 | 367,100 | +290,200 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 139,707 | +139,707 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 111,064 | +111,064 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 179,635 | 275,978 | +96,343 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 89,975 | +89,975 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 67,737 | +67,737 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 62,947 | +62,947 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 0 | 45,400 | +45,400 | 0.00 | 0.00 | +0.00 | buy |
| Jain Global LLC | 0 | 40,276 | +40,276 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 36,884 | +36,884 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 111,079 | 147,168 | +36,089 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 284,229 | 307,097 | +22,868 | 0.00 | 0.00 | -0.00 | buy |
| Abel Hall, LLC | 0 | 17,582 | +17,582 | 0.00 | 0.00 | +0.00 | buy |
| Quadrant Private Wealth Management, LLC | 0 | 15,286 | +15,286 | 0.00 | 0.00 | +0.00 | buy |
| Savant Capital, LLC | 0 | 14,769 | +14,769 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA SECURITIES, LLC | 0 | 11,767 | +11,767 | 0.00 | 0.00 | +0.00 | buy |
| Ground Swell Capital, LLC | 0 | 10,176 | +10,176 | 0.00 | 0.01 | +0.01 | buy |
| Advisors Asset Management, Inc. | 0 | 8,498 | +8,498 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 17,508 | 22,362 | +4,854 | 0.00 | 0.00 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 0 | 1,978 | +1,978 | 0.00 | 0.00 | +0.00 | buy |
| Point72 (DIFC) Ltd | 0 | 1,749 | +1,749 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 6,849 | 8,151 | +1,302 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 300 | 1,262 | +962 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 41 | 455 | +414 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 1,130 | 1,530 | +400 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 55 | 266 | +211 | 0.00 | 0.00 | +0.00 | buy |
| IFP Advisors, Inc | 0 | 6 | +6 | 0.00 | 0.00 | +0.00 | buy |
| HARBOURVEST PARTNERS LLC | 29,018 | 29,018 | 0 | 0.01 | 0.02 | +0.01 | hold |
| TANG CAPITAL MANAGEMENT LLC | 900,000 | 900,000 | 0 | 0.02 | 0.03 | +0.00 | hold |
| DAFNA Capital Management LLC | 1,704,232 | 1,704,232 | 0 | 0.23 | 0.26 | +0.03 | hold |
| Parametrica Management Ltd | 27,840 | 27,840 | 0 | 0.02 | 0.03 | +0.01 | hold |
| MARK SHEPTOFF FINANCIAL PLANNING, LLC | 500 | 500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Bain Capital Life Sciences Investors, LLC | 5,410,361 | 5,410,361 | 0 | 0.38 | 0.38 | -0.00 | hold |
| Syncona Portfolio Ltd | 1,213,056 | 1,213,056 | 0 | 2.19 | 1.76 | -0.43 | hold |
| SUPERSTRING CAPITAL MANAGEMENT LP | 462,963 | 462,963 | 0 | 0.26 | 0.32 | +0.06 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| IEQ CAPITAL, LLC | 22,841 | 22,419 | -422 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 4,282 | 3,681 | -601 | 0.00 | 0.00 | +0.00 | sell |
| AMALGAMATED BANK | 706 | 0 | -706 | 0.00 | 0.00 | 0.00 | sell |
| Sterling Capital Management LLC | 807 | 0 | -807 | 0.00 | 0.00 | -0.00 | sell |
| Ameritas Investment Partners, Inc. | 905 | 0 | -905 | 0.00 | 0.00 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,324 | 0 | -3,324 | 0.00 | 0.00 | -0.00 | sell |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 85,083 | 81,247 | -3,836 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 3,976 | 0 | -3,976 | 0.00 | 0.00 | -0.00 | sell |
| ProShare Advisors LLC | 10,131 | 0 | -10,131 | 0.00 | 0.00 | -0.00 | sell |
| CIBC WORLD MARKETS CORP | 10,384 | 0 | -10,384 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 13,743 | 0 | -13,743 | 0.00 | 0.00 | -0.00 | sell |
| Cerity Partners LLC | 14,260 | 0 | -14,260 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 14,882 | 0 | -14,882 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 32,859 | 15,973 | -16,886 | 0.00 | 0.00 | -0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 20,020 | 0 | -20,020 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 22,925 | 0 | -22,925 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 25,314 | 0 | -25,314 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 26,735 | 0 | -26,735 | 0.00 | 0.00 | -0.00 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 27,447 | 0 | -27,447 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 47,209 | 12,197 | -35,012 | 0.00 | 0.00 | -0.00 | sell |
| INTECH INVESTMENT MANAGEMENT LLC | 35,814 | 0 | -35,814 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 43,273 | 0 | -43,273 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 43,514 | 0 | -43,514 | 0.00 | 0.00 | -0.00 | sell |
| SEI INVESTMENTS CO | 52,748 | 0 | -52,748 | 0.00 | 0.00 | -0.00 | sell |
| PANAGORA ASSET MANAGEMENT INC | 90,739 | 0 | -90,739 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 132,929 | 40,480 | -92,449 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 120,500 | 26,700 | -93,800 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 96,140 | 0 | -96,140 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 105,529 | 0 | -105,529 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 270,820 | 163,377 | -107,443 | 0.00 | 0.00 | -0.00 | sell |
| Nuveen, LLC | 157,311 | 0 | -157,311 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 289,601 | 67,000 | -222,601 | 0.00 | 0.00 | -0.00 | sell |
| BAKER BROS. ADVISORS LP | 241,684 | 0 | -241,684 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 2,377,494 | 2,110,082 | -267,412 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 970,260 | 380,277 | -589,983 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 846,221 | 127,443 | -718,778 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 2,594,745 | 1,020,614 | -1,574,131 | 0.00 | 0.00 | -0.00 | sell |
| Casdin Capital, LLC | 3,212,316 | 1,228,190 | -1,984,126 | 0.12 | 0.06 | -0.06 | sell |
| BlackRock, Inc. | 3,018,515 | 924,683 | -2,093,832 | 0.00 | 0.00 | -0.00 | sell |
| VR Adviser, LLC | 2,498,069 | 0 | -2,498,069 | 0.10 | 0.00 | -0.10 | sell |