| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RENAISSANCE TECHNOLOGIES LLC | 2,022,500 | 2,586,900 | +564,400 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 367,100 | 857,600 | +490,500 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 307,097 | 719,808 | +412,711 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 572,544 | 911,446 | +338,902 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 40,480 | 236,053 | +195,573 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 466,606 | 603,479 | +136,873 | 0.02 | 0.03 | +0.01 | buy |
| RAYMOND JAMES FINANCIAL INC | 0 | 91,323 | +91,323 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 380,277 | 445,309 | +65,032 | 0.00 | 0.00 | -0.00 | buy |
| XTX Topco Ltd | 0 | 27,558 | +27,558 | 0.00 | 0.00 | +0.00 | buy |
| BLUEFIN CAPITAL MANAGEMENT, LLC | 0 | 24,018 | +24,018 | 0.00 | 0.01 | +0.01 | buy |
| PRUDENTIAL FINANCIAL INC | 45,400 | 59,800 | +14,400 | 0.00 | 0.00 | +0.00 | buy |
| Advisory Services Network, LLC | 0 | 407 | +407 | 0.00 | 0.00 | +0.00 | buy |
| Arax Advisory Partners | 0 | 99 | +99 | 0.00 | 0.00 | +0.00 | buy |
| Optiver Holding B.V. | 0 | 32 | +32 | 0.00 | 0.00 | +0.00 | buy |
| HARBOURVEST PARTNERS LLC | 29,018 | 29,018 | 0 | 0.02 | 0.01 | -0.01 | hold |
| TANG CAPITAL MANAGEMENT LLC | 900,000 | 900,000 | 0 | 0.03 | 0.02 | -0.01 | hold |
| DAFNA Capital Management LLC | 1,704,232 | 1,704,232 | 0 | 0.26 | 0.21 | -0.05 | hold |
| Casdin Capital, LLC | 1,228,190 | 1,228,190 | 0 | 0.06 | 0.05 | -0.01 | hold |
| Parametrica Management Ltd | 27,840 | 27,840 | 0 | 0.03 | 0.02 | -0.01 | hold |
| MARK SHEPTOFF FINANCIAL PLANNING, LLC | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| IFP Advisors, Inc | 6 | 6 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Syncona Portfolio Ltd | 1,213,056 | 1,213,056 | 0 | 1.76 | 2.18 | +0.42 | hold |
| Quadrant Private Wealth Management, LLC | 15,286 | 15,286 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SBI Securities Co., Ltd. | 1,530 | 1,530 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SUPERSTRING CAPITAL MANAGEMENT LP | 462,963 | 462,963 | 0 | 0.32 | 0.23 | -0.10 | hold |
| NORTHERN TRUST CORP | 67,000 | 67,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 127,443 | 127,443 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Advisors Asset Management, Inc. | 8,498 | 8,412 | -86 | 0.00 | 0.00 | -0.00 | sell |
| True Wealth Design, LLC | 266 | 0 | -266 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 1,262 | 883 | -379 | 0.00 | 0.00 | -0.00 | sell |
| EverSource Wealth Advisors, LLC | 455 | 28 | -427 | 0.00 | 0.00 | -0.00 | sell |
| Point72 (DIFC) Ltd | 1,749 | 1,064 | -685 | 0.00 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 1,978 | 0 | -1,978 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 3,681 | 1,478 | -2,203 | 0.00 | 0.00 | -0.00 | sell |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 81,247 | 77,853 | -3,394 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 2,110,082 | 2,103,869 | -6,213 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 8,151 | 0 | -8,151 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 22,362 | 13,116 | -9,246 | 0.00 | 0.00 | -0.00 | sell |
| Ground Swell Capital, LLC | 10,176 | 0 | -10,176 | 0.01 | 0.00 | -0.01 | sell |
| TWO SIGMA SECURITIES, LLC | 11,767 | 0 | -11,767 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 12,197 | 1 | -12,196 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 15,973 | 2,210 | -13,763 | 0.00 | 0.00 | -0.00 | sell |
| Savant Capital, LLC | 14,769 | 0 | -14,769 | 0.00 | 0.00 | -0.00 | sell |
| Abel Hall, LLC | 17,582 | 0 | -17,582 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asia (Singapore) Pte. Ltd. | 36,884 | 17,861 | -19,023 | 0.00 | 0.00 | -0.00 | sell |
| IEQ CAPITAL, LLC | 22,419 | 0 | -22,419 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 26,700 | 0 | -26,700 | 0.00 | 0.00 | -0.00 | sell |
| Jain Global LLC | 40,276 | 11,241 | -29,035 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 67,737 | 17,501 | -50,236 | 0.00 | 0.00 | -0.00 | sell |
| LAZARD ASSET MANAGEMENT LLC | 62,947 | 0 | -62,947 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 812,213 | 743,781 | -68,432 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 139,707 | 54,161 | -85,546 | 0.00 | 0.00 | -0.00 | sell |
| Y-Intercept (Hong Kong) Ltd | 89,975 | 0 | -89,975 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 111,064 | 18,113 | -92,951 | 0.00 | 0.00 | -0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 147,168 | 10,660 | -136,508 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 163,377 | 0 | -163,377 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 275,978 | 0 | -275,978 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 924,683 | 599,656 | -325,027 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 444,590 | 0 | -444,590 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 1,020,614 | 192,139 | -828,475 | 0.00 | 0.00 | -0.00 | sell |
| Bain Capital Life Sciences Investors, LLC | 5,410,361 | 3,538,609 | -1,871,752 | 0.38 | 0.12 | -0.26 | sell |