| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | 0 | 1,066,440 | +1,066,440 | 0.00 | 0.33 | +0.33 | buy |
| MORGAN STANLEY | 0 | 279,928 | +279,928 | 0.00 | 0.00 | +0.00 | buy |
| Avidity Partners Management LP | 1,098,500 | 1,355,000 | +256,500 | 0.09 | 0.17 | +0.08 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 138,960 | +138,960 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 30,151 | 78,215 | +48,064 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 58,591 | 99,919 | +41,328 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 87,700 | 119,200 | +31,500 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 4,149 | 32,184 | +28,035 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 1,109 | 28,491 | +27,382 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 17,528 | +17,528 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 14,177 | +14,177 | 0.00 | 0.01 | +0.01 | buy |
| Virtu Financial LLC | 0 | 14,018 | +14,018 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 76,606 | 90,556 | +13,950 | 0.00 | 0.00 | +0.00 | buy |
| Neuberger Berman Group LLC | 0 | 10,028 | +10,028 | 0.00 | 0.00 | +0.00 | buy |
| FOUNDERS FINANCIAL SECURITIES LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 1,119,170 | 1,124,653 | +5,483 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 28,026 | 32,598 | +4,572 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 464,687 | 468,457 | +3,770 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 754 | 3,518 | +2,764 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 615,982 | 618,482 | +2,500 | 0.00 | 0.01 | +0.00 | buy |
| SG Americas Securities, LLC | 10,340 | 12,818 | +2,478 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 482 | 2,852 | +2,370 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 146,801 | 148,761 | +1,960 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 446,571 | 448,491 | +1,920 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 294 | +294 | 0.00 | 0.00 | 0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 0 | 111 | +111 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 8 | +8 | 0.00 | 0.00 | +0.00 | buy |
| Covestor Ltd | 0 | 3 | +3 | 0.00 | 0.00 | 0.00 | buy |
| Ameritas Investment Partners, Inc. | 905 | 905 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CORNERCAP INVESTMENT COUNSEL INC | 51,520 | 51,520 | 0 | 0.02 | 0.03 | +0.01 | hold |
| HARBOURVEST PARTNERS LLC | 29,018 | 29,018 | 0 | 0.02 | 0.03 | +0.01 | hold |
| DAFNA Capital Management LLC | 1,307,407 | 1,307,407 | 0 | 0.81 | 1.04 | +0.23 | hold |
| Casdin Capital, LLC | 3,206,380 | 3,206,380 | 0 | 0.72 | 1.05 | +0.33 | hold |
| Parametrica Management Ltd | 27,840 | 27,840 | 0 | 0.09 | 0.15 | +0.06 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Legal & General Group Plc | 2,113 | 2,113 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 13,789 | 13,772 | -17 | 0.00 | 0.00 | +0.00 | sell |
| CWM, LLC | 45 | 0 | -45 | 0.00 | 0.00 | 0.00 | sell |
| AMERICAN INTERNATIONAL GROUP, INC. | 11,689 | 11,643 | -46 | 0.00 | 0.00 | +0.00 | sell |
| Daiwa Securities Group Inc. | 159 | 0 | -159 | 0.00 | 0.00 | 0.00 | sell |
| AMALGAMATED BANK | 2,093 | 1,883 | -210 | 0.00 | 0.00 | +0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 12,680 | 11,580 | -1,100 | 0.00 | 0.00 | +0.00 | sell |
| COMERICA BANK | 4,221 | 3,078 | -1,143 | 0.00 | 0.00 | +0.00 | sell |
| NORTHERN TRUST CORP | 187,194 | 185,979 | -1,215 | 0.00 | 0.00 | +0.00 | sell |
| RHUMBLINE ADVISERS | 34,202 | 32,946 | -1,256 | 0.00 | 0.00 | +0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 5,168 | 3,855 | -1,313 | 0.00 | 0.00 | +0.00 | sell |
| China Universal Asset Management Co., Ltd. | 1,528 | 0 | -1,528 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK LIFE INVESTMENT MANAGEMENT LLC | 102,606 | 99,912 | -2,694 | 0.00 | 0.00 | +0.00 | sell |
| GOLDMAN SACHS GROUP INC | 48,278 | 44,625 | -3,653 | 0.00 | 0.00 | +0.00 | sell |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 8,735 | 0 | -8,735 | 0.00 | 0.00 | -0.00 | sell |
| Gladius Capital Management LP | 9,810 | 0 | -9,810 | 0.01 | 0.00 | -0.01 | sell |
| AMERIPRISE FINANCIAL INC | 18,400 | 0 | -18,400 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 27,851 | 3,950 | -23,901 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 85,700 | 55,817 | -29,883 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 46,873 | 6,947 | -39,926 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 165,000 | 120,100 | -44,900 | 0.01 | 0.01 | +0.00 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 171,282 | 101,026 | -70,256 | 0.00 | 0.00 | -0.00 | sell |
| BAKER BROS. ADVISORS LP | 1,149,340 | 797,460 | -351,880 | 0.01 | 0.03 | +0.02 | sell |
| Deep Track Capital, LP | 543,008 | 0 | -543,008 | 0.04 | 0.00 | -0.04 | sell |
| FMR LLC | 4,524,629 | 3,612,551 | -912,078 | 0.00 | 0.00 | +0.00 | sell |