| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VR Adviser, LLC | 2,023,166 | 5,023,166 | +3,000,000 | 0.35 | 0.55 | +0.20 | buy |
| Allostery Investments LP | 1,515,126 | 2,329,384 | +814,258 | 7.44 | 4.33 | -3.10 | buy |
| ADAR1 Capital Management, LLC | 2,077,251 | 2,801,184 | +723,933 | 1.07 | 0.70 | -0.37 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 129,114 | 422,223 | +293,109 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 12,800 | 86,900 | +74,100 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 55,702 | +55,702 | 0.00 | 0.00 | +0.00 | buy |
| Forefront Analytics, LLC | 53,734 | 108,308 | +54,574 | 0.06 | 0.16 | +0.10 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 955,426 | 993,016 | +37,590 | 0.00 | 0.00 | -0.00 | buy |
| ARMISTICE CAPITAL, LLC | 1,500,000 | 1,536,000 | +36,000 | 0.09 | 0.05 | -0.03 | buy |
| STATE STREET CORP | 509,599 | 522,292 | +12,693 | 0.00 | 0.00 | -0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 10,552 | 22,702 | +12,150 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 0 | 11,200 | +11,200 | 0.00 | 0.00 | +0.00 | buy |
| Savant Capital, LLC | 0 | 11,160 | +11,160 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 2,713,464 | 2,721,752 | +8,288 | 0.00 | 0.00 | -0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 21,764 | 29,545 | +7,781 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 25,474 | 30,820 | +5,346 | 0.00 | 0.00 | -0.00 | buy |
| FNY Investment Advisers, LLC | 0 | 5,000 | +5,000 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 3,714 | 7,848 | +4,134 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 1,069 | 4,955 | +3,886 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 7,055 | 9,241 | +2,186 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 1,346 | 3,443 | +2,097 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 988 | 2,660 | +1,672 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 256 | 1,703 | +1,447 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 0 | 1,369 | +1,369 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 60 | 684 | +624 | 0.00 | 0.00 | +0.00 | buy |
| Corebridge Financial, Inc. | 24,528 | 24,728 | +200 | 0.00 | 0.00 | -0.00 | buy |
| True Wealth Design, LLC | 0 | 95 | +95 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 732 | 792 | +60 | 0.00 | 0.00 | -0.00 | buy |
| MAI Capital Management | 4,000 | 4,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ameritas Investment Partners, Inc. | 4,497 | 4,497 | 0 | 0.00 | 0.00 | -0.00 | hold |
| VOYA INVESTMENT MANAGEMENT LLC | 15,439 | 15,439 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,739 | 3,739 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 28,840 | 28,840 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GREAT POINT PARTNERS LLC | 3,170,194 | 3,170,194 | 0 | 3.73 | 2.22 | -1.51 | hold |
| Sterling Capital Management LLC | 53 | 53 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RA CAPITAL MANAGEMENT, L.P. | 3,217,503 | 3,217,503 | 0 | 0.11 | 0.07 | -0.04 | hold |
| Bank of New York Mellon Corp | 85,917 | 85,917 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 11,250 | 11,250 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 4,860,939 | 4,860,939 | 0 | 0.45 | 0.25 | -0.20 | hold |
| IFP Advisors, Inc | 14 | 14 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CLEAR STREET LLC | 1,681 | 1,681 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Affinity Asset Advisors, LLC | 223,335 | 223,335 | 0 | 0.09 | 0.05 | -0.04 | hold |
| Woodline Partners LP | 520,276 | 520,276 | 0 | 0.01 | 0.00 | -0.00 | hold |
| Deep Track Capital, LP | 3,283,783 | 3,283,783 | 0 | 0.31 | 0.14 | -0.17 | hold |
| BRAIDWELL LP | 2,472,806 | 2,472,806 | 0 | 0.18 | 0.11 | -0.07 | hold |
| Police & Firemen's Retirement System of New Jersey | 9,812 | 9,812 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Legal & General Group Plc | 4,779 | 4,779 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PFIZER INC | 2,970,022 | 2,970,022 | 0 | 0.29 | 0.76 | +0.48 | hold |
| PRICE T ROWE ASSOCIATES INC /MD/ | 20,830 | 20,830 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 8,547 | 8,547 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STRS OHIO | 1,500 | 1,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SIMPLEX TRADING, LLC | 505 | 0 | -505 | 0.00 | 0.00 | -0.00 | sell |
| Federation des caisses Desjardins du Quebec | 600 | 0 | -600 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 37,657 | 36,577 | -1,080 | 0.00 | 0.00 | -0.00 | sell |
| ProShare Advisors LLC | 13,894 | 10,927 | -2,967 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 23,005 | 19,460 | -3,545 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 39,566 | 35,968 | -3,598 | 0.00 | 0.00 | -0.00 | sell |
| RAYMOND JAMES FINANCIAL INC | 148,500 | 144,685 | -3,815 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 296,161 | 288,601 | -7,560 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 23,372 | 15,238 | -8,134 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 10,816 | 0 | -10,816 | 0.00 | 0.00 | -0.00 | sell |
| PRUDENTIAL FINANCIAL INC | 11,105 | 0 | -11,105 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 106,626 | 94,055 | -12,571 | 0.00 | 0.00 | -0.00 | sell |
| PRELUDE CAPITAL MANAGEMENT, LLC | 16,200 | 0 | -16,200 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 17,610 | 0 | -17,610 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 17,785 | 0 | -17,785 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 144,083 | 122,976 | -21,107 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 78,523 | 55,759 | -22,764 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 23,053 | 0 | -23,053 | 0.00 | 0.00 | -0.00 | sell |
| Jump Financial, LLC | 23,701 | 0 | -23,701 | 0.00 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 24,675 | 0 | -24,675 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 2,633,185 | 2,607,219 | -25,966 | 0.00 | 0.00 | -0.00 | sell |
| Aristides Capital LLC | 29,600 | 0 | -29,600 | 0.02 | 0.00 | -0.02 | sell |
| NORTHERN TRUST CORP | 401,994 | 369,358 | -32,636 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 37,290 | 0 | -37,290 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 879,899 | 842,158 | -37,741 | 0.00 | 0.00 | -0.00 | sell |
| Hudson Bay Capital Management LP | 38,999 | 0 | -38,999 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asset Management, L.P. | 2,413,127 | 2,350,000 | -63,127 | 0.02 | 0.01 | -0.01 | sell |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 80,912 | 0 | -80,912 | 0.01 | 0.00 | -0.01 | sell |
| Shay Capital LLC | 93,119 | 0 | -93,119 | 0.06 | 0.00 | -0.06 | sell |
| Caption Management, LLC | 175,987 | 0 | -175,987 | 0.02 | 0.00 | -0.02 | sell |
| SUPERSTRING CAPITAL MANAGEMENT LP | 186,943 | 0 | -186,943 | 0.41 | 0.00 | -0.41 | sell |
| SPHERA FUNDS MANAGEMENT LTD. | 690,718 | 421,229 | -269,489 | 0.32 | 0.13 | -0.18 | sell |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 300,000 | 0 | -300,000 | 0.00 | 0.00 | -0.00 | sell |
| Boxer Capital Management, LLC | 300,000 | 0 | -300,000 | 0.06 | 0.00 | -0.06 | sell |
| MILLENNIUM MANAGEMENT LLC | 701,278 | 303,573 | -397,705 | 0.00 | 0.00 | -0.00 | sell |