| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VR Adviser, LLC | 0 | 6,023,166 | +6,023,166 | 0.00 | 1.34 | +1.34 | buy |
| RA CAPITAL MANAGEMENT, L.P. | 0 | 3,217,503 | +3,217,503 | 0.00 | 0.15 | +0.15 | buy |
| Point72 Asset Management, L.P. | 0 | 2,413,127 | +2,413,127 | 0.00 | 0.03 | +0.03 | buy |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 2,850,000 | 4,860,939 | +2,010,939 | 0.31 | 0.69 | +0.39 | buy |
| GREAT POINT PARTNERS LLC | 2,757,740 | 4,642,241 | +1,884,501 | 1.10 | 3.11 | +2.01 | buy |
| ARMISTICE CAPITAL, LLC | 1,648,000 | 2,524,000 | +876,000 | 0.11 | 0.23 | +0.12 | buy |
| Deep Track Capital, LP | 2,523,000 | 3,283,783 | +760,783 | 0.19 | 0.34 | +0.16 | buy |
| Woodline Partners LP | 0 | 515,899 | +515,899 | 0.00 | 0.02 | +0.02 | buy |
| Polar Asset Management Partners Inc. | 0 | 259,241 | +259,241 | 0.00 | 0.02 | +0.02 | buy |
| SUPERSTRING CAPITAL MANAGEMENT LP | 0 | 156,626 | +156,626 | 0.00 | 0.69 | +0.69 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0 | 73,396 | +73,396 | 0.00 | 0.01 | +0.01 | buy |
| STATE STREET CORP | 214,748 | 267,759 | +53,011 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 51,737 | +51,737 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 487,125 | 535,080 | +47,955 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 575,092 | 612,389 | +37,297 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 12,319 | +12,319 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 0 | 11,279 | +11,279 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 183,242 | 192,835 | +9,593 | 0.00 | 0.00 | +0.00 | buy |
| Forefront Analytics, LLC | 34,038 | 41,569 | +7,531 | 0.04 | 0.07 | +0.03 | buy |
| Bank of New York Mellon Corp | 40,697 | 47,109 | +6,412 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 11,500 | 17,400 | +5,900 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 25,090 | 28,840 | +3,750 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 4,307 | 7,221 | +2,914 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 0 | 1,906 | +1,906 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 15,523 | 16,894 | +1,371 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 3,195 | 4,357 | +1,162 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 0 | 628 | +628 | 0.00 | 0.00 | +0.00 | buy |
| Arax Advisory Partners | 0 | 245 | +245 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 0 | 187 | +187 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 172,717 | 172,853 | +136 | 0.00 | 0.00 | +0.00 | buy |
| Capital Advisors, Ltd. LLC | 33 | 138 | +105 | 0.00 | 0.00 | 0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 0 | 6 | +6 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 626 | 626 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Hudson Bay Capital Management LP | 38,999 | 38,999 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SILVERARC CAPITAL MANAGEMENT, LLC | 328,504 | 328,504 | 0 | 0.24 | 0.28 | +0.05 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 8,547 | 8,547 | 0 | 0.00 | 0.00 | +0.00 | hold |
| STRS OHIO | 1,500 | 1,500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| AMALGAMATED BANK | 256 | 256 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Impact Partnership Wealth, LLC | 6 | 0 | -6 | 0.00 | 0.00 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 1,934 | 1,450 | -484 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 2,962 | 2,308 | -654 | 0.00 | 0.00 | +0.00 | sell |
| BARCLAYS PLC | 12,336 | 7,304 | -5,032 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN INTERNATIONAL GROUP, INC. | 8,396 | 0 | -8,396 | 0.00 | 0.00 | -0.00 | sell |
| Atom Investors LP | 94,982 | 77,416 | -17,566 | 0.03 | 0.03 | -0.00 | sell |
| OCCUDO QUANTITATIVE STRATEGIES LP | 19,042 | 0 | -19,042 | 0.01 | 0.00 | -0.01 | sell |
| Invesco Ltd. | 21,456 | 0 | -21,456 | 0.00 | 0.00 | -0.00 | sell |
| METEORA CAPITAL, LLC | 28,702 | 0 | -28,702 | 0.01 | 0.00 | -0.01 | sell |
| CITADEL ADVISORS LLC | 681,420 | 633,663 | -47,757 | 0.00 | 0.00 | +0.00 | sell |
| Calamos Advisors LLC | 200,000 | 0 | -200,000 | 0.00 | 0.00 | -0.00 | sell |
| Affinity Asset Advisors, LLC | 450,009 | 223,335 | -226,674 | 0.19 | 0.12 | -0.06 | sell |