| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Samsara BioCapital, LLC | 8,500,000 | 10,369,159 | +1,869,159 | 0.61 | 0.65 | +0.04 | buy |
| RA CAPITAL MANAGEMENT, L.P. | 8,500,000 | 8,500,000 | 0 | 0.07 | 0.06 | -0.01 | hold |
| AWM Investment Company, Inc. | 6,500,000 | 7,500,000 | +1,000,000 | 0.53 | 0.49 | -0.03 | buy |
| Longaeva Partners L.P. | 2,329,459 | 2,329,459 | 0 | 0.08 | 0.05 | -0.03 | hold |
| Polar Asset Management Partners Inc. | 0 | 2,318,542 | +2,318,542 | 0.00 | 0.03 | +0.03 | buy |
| Siren, L.L.C. | 2,000,000 | 2,000,000 | 0 | 0.04 | 0.03 | -0.01 | hold |
| HEIGHTS CAPITAL MANAGEMENT, INC | 0 | 934,580 | +934,580 | 0.00 | 0.16 | +0.16 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 903,298 | 890,618 | -12,680 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 0 | 641,995 | +641,995 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 586,265 | +586,265 | 0.00 | 0.00 | +0.00 | buy |
| Nan Fung Group Holdings Ltd | 493,584 | 493,584 | 0 | 0.30 | 0.29 | -0.01 | hold |
| JANE STREET GROUP, LLC | 0 | 485,899 | +485,899 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 430,737 | +430,737 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 373,142 | 373,142 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BlackRock, Inc. | 556,889 | 342,113 | -214,776 | 0.00 | 0.00 | -0.00 | sell |
| UNITED SERVICES AUTOMOBILE ASSOCIATION | 302,743 | 302,743 | 0 | 0.03 | 0.02 | -0.01 | hold |
| KESTRA PRIVATE WEALTH SERVICES, LLC | 265,159 | 282,340 | +17,181 | 0.00 | 0.00 | -0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 96,998 | 249,716 | +152,718 | 0.00 | 0.01 | +0.01 | buy |
| NORTHERN TRUST CORP | 170,471 | 170,471 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CWA Asset Management Group, LLC | 150,000 | 150,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 114,500 | 114,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| KING LUTHER CAPITAL MANAGEMENT CORP | 58,000 | 58,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Well Done, LLC | 52,014 | 52,014 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Janney Montgomery Scott LLC | 49,200 | 49,200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MOTCO | 48,129 | 48,129 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Squarepoint Ops LLC | 16,401 | 41,902 | +25,501 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 12,318 | 29,743 | +17,425 | 0.00 | 0.00 | +0.00 | buy |
| Lafayette Investments, Inc. | 22,979 | 22,979 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TRAPHAGEN INVESTMENT ADVISORS LLC | 22,024 | 22,024 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FARALLON CAPITAL MANAGEMENT LLC | 78,000 | 20,700 | -57,300 | 0.00 | 0.00 | -0.00 | sell |
| Cerity Partners LLC | 19,090 | 19,090 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 10,502 | 19,051 | +8,549 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 17,311 | 17,887 | +576 | 0.00 | 0.00 | -0.00 | buy |
| J. Safra Sarasin Holding AG | 0 | 17,000 | +17,000 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 16,959 | +16,959 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 14,350 | 15,509 | +1,159 | 0.00 | 0.00 | -0.00 | buy |
| ACT Advisors, LLC. | 14,806 | 14,806 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Bank of New York Mellon Corp | 13,879 | 13,879 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Farther Finance Advisors, LLC | 13,800 | 13,800 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Disciplined Investors, L.L.C. | 12,200 | 12,200 | 0 | 0.01 | 0.00 | -0.00 | hold |
| Rockefeller Capital Management L.P. | 0 | 11,545 | +11,545 | 0.00 | 0.00 | +0.00 | buy |
| Prime Capital Investment Advisors, LLC | 11,485 | 11,485 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CARY STREET PARTNERS FINANCIAL LLC | 10,550 | 10,550 | 0 | 0.00 | 0.00 | -0.00 | hold |
| EWA, LLC | 10,817 | 10,520 | -297 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 10,246 | 10,036 | -210 | 0.00 | 0.00 | -0.00 | sell |
| ISLAY CAPITAL MANAGEMENT, LLC | 9,611 | 9,611 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SIMPLEX TRADING, LLC | 10,101 | 5,136 | -4,965 | 0.00 | 0.00 | -0.00 | sell |
| Mirae Asset Global Investments Co., Ltd. | 5,088 | 5,026 | -62 | 0.00 | 0.00 | -0.00 | sell |
| GROUP ONE TRADING LLC | 0 | 3,724 | +3,724 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 3,119 | 3,119 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CITIGROUP INC | 2,726 | 2,643 | -83 | 0.00 | 0.00 | -0.00 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 5,899 | 2,206 | -3,693 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 1,543 | 2,134 | +591 | 0.00 | 0.00 | +0.00 | buy |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0 | 1,100 | +1,100 | 0.00 | 0.00 | +0.00 | buy |
| OMERS ADMINISTRATION Corp | 76,500 | 0 | -76,500 | 0.00 | 0.00 | -0.00 | sell |
| FEDERATED HERMES, INC. | 799 | 0 | -799 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 405,669 | 0 | -405,669 | 0.00 | 0.00 | -0.00 | sell |
| Hudson Bay Capital Management LP | 153,331 | 0 | -153,331 | 0.00 | 0.00 | -0.00 | sell |
| 683 Capital Management, LLC | 487,168 | 0 | -487,168 | 0.03 | 0.00 | -0.03 | sell |
| Bronte Capital Management Pty Ltd. | 14,868 | 0 | -14,868 | 0.00 | 0.00 | -0.00 | sell |
| Brevan Howard Capital Management LP | 23,336 | 0 | -23,336 | 0.00 | 0.00 | -0.00 | sell |
| NINE MASTS CAPITAL Ltd | 44,849 | 0 | -44,849 | 0.01 | 0.00 | -0.01 | sell |
| CTC Alternative Strategies, Ltd. | 23,622 | 0 | -23,622 | 0.04 | 0.00 | -0.04 | sell |
| Schonfeld Strategic Advisors LLC | 14,200 | 0 | -14,200 | 0.00 | 0.00 | -0.00 | sell |
| Diametric Capital, LP | 33,208 | 0 | -33,208 | 0.01 | 0.00 | -0.01 | sell |
| Qube Research & Technologies Ltd | 47,508 | 0 | -47,508 | 0.00 | 0.00 | -0.00 | sell |
| Catalyst Funds Management Pty Ltd | 14,800 | 0 | -14,800 | 0.00 | 0.00 | -0.00 | sell |
| GF FUND MANAGEMENT CO. LTD. | 2,175 | 0 | -2,175 | 0.00 | 0.00 | -0.00 | sell |
| Jefferies Financial Group Inc. | 22,221 | 0 | -22,221 | 0.00 | 0.00 | -0.00 | sell |