| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 0 | 8,500,000 | +8,500,000 | 0.00 | 0.12 | +0.12 | buy |
| Samsara BioCapital, LLC | 0 | 8,500,000 | +8,500,000 | 0.00 | 1.18 | +1.18 | buy |
| AWM Investment Company, Inc. | 0 | 6,500,000 | +6,500,000 | 0.00 | 0.85 | +0.85 | buy |
| VANGUARD GROUP INC | 884,609 | 5,109,368 | +4,224,759 | 0.00 | 0.00 | +0.00 | buy |
| Longaeva Partners L.P. | 0 | 2,113,435 | +2,113,435 | 0.00 | 0.34 | +0.34 | buy |
| Siren, L.L.C. | 0 | 2,000,000 | +2,000,000 | 0.00 | 0.08 | +0.08 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 296,910 | 860,941 | +564,031 | 0.00 | 0.00 | +0.00 | buy |
| 683 Capital Management, LLC | 0 | 487,168 | +487,168 | 0.00 | 0.05 | +0.05 | buy |
| BlackRock, Inc. | 120,232 | 527,712 | +407,480 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 344,378 | +344,378 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 62,442 | 387,042 | +324,600 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 0 | 285,832 | +285,832 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 163,300 | +163,300 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 148,226 | +148,226 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 0 | 114,500 | +114,500 | 0.00 | 0.00 | +0.00 | buy |
| FARALLON CAPITAL MANAGEMENT LLC | 0 | 78,000 | +78,000 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 97,005 | 170,471 | +73,466 | 0.00 | 0.00 | +0.00 | buy |
| OMERS ADMINISTRATION Corp | 0 | 69,200 | +69,200 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 53,095 | +53,095 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 51,178 | +51,178 | 0.00 | 0.00 | +0.00 | buy |
| Lighthouse Investment Partners, LLC | 0 | 42,840 | +42,840 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA SECURITIES, LLC | 0 | 35,874 | +35,874 | 0.00 | 0.01 | +0.01 | buy |
| Jefferies Financial Group Inc. | 0 | 29,870 | +29,870 | 0.00 | 0.00 | +0.00 | buy |
| KESTRA PRIVATE WEALTH SERVICES, LLC | 226,142 | 254,812 | +28,670 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 0 | 15,894 | +15,894 | 0.00 | 0.00 | +0.00 | buy |
| Bronte Capital Management Pty Ltd. | 0 | 14,868 | +14,868 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 14,655 | +14,655 | 0.00 | 0.00 | +0.00 | buy |
| Farther Finance Advisors, LLC | 0 | 13,800 | +13,800 | 0.00 | 0.00 | +0.00 | buy |
| Disciplined Investors, L.L.C. | 0 | 12,200 | +12,200 | 0.00 | 0.01 | +0.01 | buy |
| EWA, LLC | 0 | 11,081 | +11,081 | 0.00 | 0.00 | +0.00 | buy |
| CARY STREET PARTNERS FINANCIAL LLC | 0 | 10,550 | +10,550 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 0 | 8,096 | +8,096 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 0 | 4,740 | +4,740 | 0.00 | 0.00 | +0.00 | buy |
| Lafayette Investments, Inc. | 19,893 | 22,979 | +3,086 | 0.00 | 0.01 | +0.00 | buy |
| State of Wyoming | 0 | 2,076 | +2,076 | 0.00 | 0.00 | +0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 0 | 1,857 | +1,857 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 1,616 | +1,616 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 6,224 | 7,685 | +1,461 | 0.00 | 0.00 | +0.00 | buy |
| ACT Advisors, LLC. | 14,806 | 16,062 | +1,256 | 0.00 | 0.01 | +0.01 | buy |
| SBI Securities Co., Ltd. | 12,632 | 13,788 | +1,156 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| Elyxium Wealth, LLC | 0 | 760 | +760 | 0.00 | 0.00 | +0.00 | buy |
| UNITED SERVICES AUTOMOBILE ASSOCIATION | 302,743 | 302,743 | 0 | 0.01 | 0.03 | +0.02 | hold |
| MOTCO | 48,129 | 48,129 | 0 | 0.00 | 0.01 | +0.00 | hold |
| Janney Montgomery Scott LLC | 49,200 | 49,200 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Allworth Financial LP | 3,119 | 3,119 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Cerity Partners LLC | 10,000 | 10,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Well Done, LLC | 52,014 | 52,014 | 0 | 0.00 | 0.01 | +0.01 | hold |
| CWA Asset Management Group, LLC | 150,000 | 150,000 | 0 | 0.00 | 0.01 | +0.00 | hold |
| Prime Capital Investment Advisors, LLC | 27,208 | 27,208 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ISLAY CAPITAL MANAGEMENT, LLC | 9,611 | 9,611 | 0 | 0.00 | 0.01 | +0.00 | hold |
| Nan Fung Group Holdings Ltd | 493,584 | 493,584 | 0 | 0.41 | 0.60 | +0.18 | hold |
| KING LUTHER CAPITAL MANAGEMENT CORP | 58,000 | 58,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SIMPLEX TRADING, LLC | 819 | 0 | -819 | 0.00 | 0.00 | 0.00 | sell |
| EverSource Wealth Advisors, LLC | 980 | 0 | -980 | 0.00 | 0.00 | -0.00 | sell |
| CHOREO, LLC | 11,813 | 0 | -11,813 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 24,908 | 0 | -24,908 | 0.00 | 0.00 | -0.00 | sell |
| BROWN ADVISORY INC | 32,911 | 0 | -32,911 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 44,077 | 0 | -44,077 | 0.00 | 0.00 | -0.00 | sell |
| INSIGNEO ADVISORY SERVICES, LLC | 47,500 | 0 | -47,500 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 113,206 | 0 | -113,206 | 0.00 | 0.00 | -0.00 | sell |