| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 16,616 | 1,310,196 | +1,293,580 | 0.00 | 0.05 | +0.05 | buy |
| BRAIDWELL LP | 241,235 | 840,945 | +599,710 | 0.56 | 2.10 | +1.54 | buy |
| Logos Global Management LP | 0 | 500,000 | +500,000 | 0.00 | 6.30 | +6.30 | buy |
| Vestal Point Capital, LP | 600,000 | 1,075,000 | +475,000 | 2.78 | 5.44 | +2.66 | buy |
| T. Rowe Price Investment Management, Inc. | 0 | 450,774 | +450,774 | 0.00 | 0.02 | +0.02 | buy |
| FMR LLC | 9,654,326 | 9,937,193 | +282,867 | 0.05 | 0.04 | -0.00 | buy |
| Commodore Capital LP | 1,621,600 | 1,855,000 | +233,400 | 9.30 | 9.69 | +0.39 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 184,801 | +184,801 | 0.00 | 0.09 | +0.09 | buy |
| Affinity Asset Advisors, LLC | 285,000 | 460,000 | +175,000 | 3.49 | 5.11 | +1.62 | buy |
| GOLDMAN SACHS GROUP INC | 293,747 | 453,620 | +159,873 | 0.00 | 0.01 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 1,284,575 | 1,442,384 | +157,809 | 0.02 | 0.02 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,297,910 | 1,450,602 | +152,692 | 0.01 | 0.01 | +0.00 | buy |
| MORGAN STANLEY | 222,284 | 348,080 | +125,796 | 0.00 | 0.00 | +0.00 | buy |
| Fisher Asset Management, LLC | 0 | 121,338 | +121,338 | 0.00 | 0.00 | +0.00 | buy |
| Ensign Peak Advisors, Inc | 9,472 | 128,416 | +118,944 | 0.00 | 0.02 | +0.02 | buy |
| CITIGROUP INC | 124,375 | 236,894 | +112,519 | 0.01 | 0.01 | +0.00 | buy |
| Soleus Capital Management, L.P. | 104,357 | 214,357 | +110,000 | 0.62 | 1.19 | +0.57 | buy |
| Russell Investments Group, Ltd. | 782 | 110,356 | +109,574 | 0.00 | 0.01 | +0.01 | buy |
| Tri Locum Partners LP | 0 | 95,825 | +95,825 | 0.00 | 3.49 | +3.49 | buy |
| AMERICAN CENTURY COMPANIES INC | 186,385 | 282,046 | +95,661 | 0.01 | 0.01 | +0.00 | buy |
| Parkman Healthcare Partners LLC | 23,588 | 109,988 | +86,400 | 0.25 | 0.93 | +0.68 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 170,844 | 247,046 | +76,202 | 0.05 | 0.06 | +0.02 | buy |
| MARSHALL WACE, LLP | 361,040 | 421,513 | +60,473 | 0.04 | 0.04 | +0.00 | buy |
| Edgestream Partners, L.P. | 11,724 | 68,101 | +56,377 | 0.04 | 0.16 | +0.12 | buy |
| UBS Group AG | 54,840 | 109,479 | +54,639 | 0.00 | 0.00 | +0.00 | buy |
| Whipplewood Advisors, LLC | 49 | 46,656 | +46,607 | 0.00 | 0.00 | -0.00 | buy |
| STEMPOINT CAPITAL LP | 145,234 | 190,401 | +45,167 | 2.85 | 4.31 | +1.46 | buy |
| AMERIPRISE FINANCIAL INC | 237,556 | 280,341 | +42,785 | 0.00 | 0.01 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 17,366 | 58,779 | +41,413 | 0.00 | 0.00 | +0.00 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 400,014 | 439,018 | +39,004 | 7.00 | 6.50 | -0.50 | buy |
| Jefferies Financial Group Inc. | 145 | 34,940 | +34,795 | 0.00 | 0.04 | +0.04 | buy |
| Nicholas Investment Partners, LP | 76,427 | 106,719 | +30,292 | 0.53 | 0.78 | +0.25 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 44,315 | 73,221 | +28,906 | 0.01 | 0.01 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 20,173 | 48,956 | +28,783 | 0.00 | 0.01 | +0.00 | buy |
| Squarepoint Ops LLC | 30,706 | 58,855 | +28,149 | 0.01 | 0.01 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 43,666 | 67,078 | +23,412 | 0.00 | 0.00 | +0.00 | buy |
| First Turn Management, LLC | 309,521 | 331,927 | +22,406 | 4.34 | 4.75 | +0.41 | buy |
| NEOS Investment Management LLC | 11,617 | 33,794 | +22,177 | 0.02 | 0.05 | +0.02 | buy |
| TEMA ETFS LLC | 11,617 | 33,794 | +22,177 | 0.38 | 0.72 | +0.34 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 871,488 | 893,456 | +21,968 | 0.01 | 0.00 | -0.00 | buy |
| Voleon Capital Management LP | 0 | 20,994 | +20,994 | 0.00 | 0.12 | +0.12 | buy |
| Aberdeen Group plc | 56,701 | 76,688 | +19,987 | 0.01 | 0.01 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 9,100 | 28,700 | +19,600 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 82,527 | 101,991 | +19,464 | 0.00 | 0.00 | +0.00 | buy |
| Aquatic Capital Management LLC | 18,028 | 34,576 | +16,548 | 0.04 | 0.06 | +0.02 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 137,818 | 149,941 | +12,123 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 48,372 | 59,449 | +11,077 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 10,205 | +10,205 | 0.00 | 0.04 | +0.04 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 112,897 | 120,311 | +7,414 | 0.01 | 0.01 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 20,135 | 26,527 | +6,392 | 0.00 | 0.00 | +0.00 | buy |
| DARK FOREST CAPITAL MANAGEMENT LP | 0 | 6,222 | +6,222 | 0.00 | 0.02 | +0.02 | buy |
| Creative Planning | 2,964 | 8,209 | +5,245 | 0.00 | 0.00 | +0.00 | buy |
| Bridgefront Capital, LLC | 0 | 5,053 | +5,053 | 0.00 | 0.10 | +0.10 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 36,005 | 40,674 | +4,669 | 0.01 | 0.01 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 3,288 | 7,798 | +4,510 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 14,969 | 19,262 | +4,293 | 0.01 | 0.01 | +0.00 | buy |
| SIH Partners, LLLP | 0 | 4,169 | +4,169 | 0.00 | 0.03 | +0.03 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 16,971 | 20,936 | +3,965 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 5,993 | 9,874 | +3,881 | 0.00 | 0.00 | +0.00 | buy |
| Legato Capital Management LLC | 5,451 | 8,871 | +3,420 | 0.06 | 0.08 | +0.03 | buy |
| HSBC HOLDINGS PLC | 5,080 | 8,318 | +3,238 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 10,793 | 13,946 | +3,153 | 0.00 | 0.00 | -0.00 | buy |
| AlphaQuest LLC | 107 | 2,742 | +2,635 | 0.00 | 0.02 | +0.02 | buy |
| RHUMBLINE ADVISERS | 50,454 | 53,026 | +2,572 | 0.00 | 0.00 | -0.00 | buy |
| Invesco Ltd. | 63,525 | 65,674 | +2,149 | 0.00 | 0.00 | -0.00 | buy |
| Virtus Investment Advisers, LLC | 0 | 1,890 | +1,890 | 0.00 | 0.04 | +0.04 | buy |
| State of New Jersey Common Pension Fund D | 23,053 | 24,792 | +1,739 | 0.01 | 0.01 | +0.00 | buy |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 7,808 | 9,305 | +1,497 | 0.01 | 0.01 | +0.00 | buy |
| Legal & General Group Plc | 40,387 | 41,306 | +919 | 0.00 | 0.00 | -0.00 | buy |
| Covestor Ltd | 122 | 983 | +861 | 0.01 | 0.05 | +0.04 | buy |
| US BANCORP \DE\ | 1,156 | 1,836 | +680 | 0.00 | 0.00 | +0.00 | buy |
| Woodline Partners LP | 1,204,927 | 1,205,531 | +604 | 0.64 | 0.56 | -0.08 | buy |
| E Fund Management Co., Ltd. | 4,213 | 4,785 | +572 | 0.02 | 0.02 | -0.00 | buy |
| ANTIPODES PARTNERS Ltd | 0 | 540 | +540 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 61 | 420 | +359 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 7,378 | 7,718 | +340 | 0.01 | 0.01 | -0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 1,378 | 1,680 | +302 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 21,220 | 21,457 | +237 | 0.00 | 0.00 | -0.00 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 162 | +162 | 0.00 | 0.00 | +0.00 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 1,493 | 1,654 | +161 | 0.00 | 0.00 | -0.00 | buy |
| Spire Wealth Management | 0 | 140 | +140 | 0.00 | 0.00 | +0.00 | buy |
| Rise Advisors, LLC | 0 | 124 | +124 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 1,105 | 1,217 | +112 | 0.00 | 0.00 | +0.00 | buy |
| Optiver Holding B.V. | 0 | 73 | +73 | 0.00 | 0.00 | +0.00 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 5,240 | 5,308 | +68 | 0.01 | 0.01 | -0.00 | buy |
| Versant Capital Management, Inc | 0 | 38 | +38 | 0.00 | 0.00 | +0.00 | buy |
| Parallel Advisors, LLC | 1 | 30 | +29 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 2,187 | 2,214 | +27 | 0.00 | 0.00 | -0.00 | buy |
| EverSource Wealth Advisors, LLC | 24 | 49 | +25 | 0.00 | 0.00 | +0.00 | buy |
| SIERRA OCEAN, LLC | 0 | 13 | +13 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 388 | 401 | +13 | 0.00 | 0.00 | +0.00 | buy |
| CI INVESTMENTS INC. | 65 | 75 | +10 | 0.00 | 0.00 | +0.00 | buy |
| Parkside Financial Bank & Trust | 0 | 10 | +10 | 0.00 | 0.00 | +0.00 | buy |
| Stephens Consulting, LLC | 0 | 10 | +10 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 45 | 55 | +10 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 0 | 8 | +8 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 0 | 7 | +7 | 0.00 | 0.00 | +0.00 | buy |
| SouthState Corp | 0 | 7 | +7 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 0 | 5 | +5 | 0.00 | 0.00 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 159,628 | 159,630 | +2 | 0.00 | 0.00 | -0.00 | buy |