| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Opaleye Management Inc. | 53,282 | 700,000 | +646,718 | 0.06 | 0.48 | +0.42 | buy |
| ARMISTICE CAPITAL, LLC | 1,328,000 | 1,764,000 | +436,000 | 0.21 | 0.16 | -0.05 | buy |
| Granahan Investment Management, LLC | 231,040 | 558,526 | +327,486 | 0.10 | 0.15 | +0.05 | buy |
| Laurion Capital Management LP | 1,922,656 | 2,002,701 | +80,045 | 0.75 | 0.39 | -0.36 | buy |
| Novo Holdings A/S | 2,185,923 | 2,250,000 | +64,077 | 1.59 | 1.00 | -0.59 | buy |
| TEMA ETFS LLC | 82,172 | 93,339 | +11,167 | 0.05 | 0.02 | -0.03 | buy |