| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ICONIQ Capital, LLC | 0 | 3,398,628 | +3,398,628 | 0.00 | 1.08 | +1.08 | buy |
| JOHNSON & JOHNSON | 912,128 | 1,849,445 | +937,317 | 4.74 | 0.72 | -4.02 | buy |
| FMR LLC | 5,624,353 | 6,373,129 | +748,776 | 0.01 | 0.01 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 73,600 | 592,422 | +518,822 | 0.00 | 0.00 | +0.00 | buy |
| Logos Global Management LP | 0 | 382,345 | +382,345 | 0.00 | 0.72 | +0.72 | buy |
| VANGUARD GROUP INC | 50,000 | 380,954 | +330,954 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 122,186 | 436,877 | +314,691 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 263,000 | +263,000 | 0.00 | 0.04 | +0.04 | buy |
| Alphabet Inc. | 199,608 | 404,732 | +205,124 | 0.18 | 0.32 | +0.14 | buy |
| Avidity Partners Management LP | 1,800,000 | 1,990,632 | +190,632 | 1.02 | 1.30 | +0.28 | buy |
| STATE STREET CORP | 0 | 141,478 | +141,478 | 0.00 | 0.00 | +0.00 | buy |
| GMT CAPITAL CORP | 0 | 140,666 | +140,666 | 0.00 | 0.09 | +0.09 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0 | 129,912 | +129,912 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 0 | 126,444 | +126,444 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 0 | 105,990 | +105,990 | 0.00 | 0.01 | +0.01 | buy |
| JANE STREET GROUP, LLC | 0 | 89,339 | +89,339 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 0 | 61,117 | +61,117 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 46,883 | +46,883 | 0.00 | 0.07 | +0.07 | buy |
| Bank of New York Mellon Corp | 0 | 45,200 | +45,200 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 0 | 27,355 | +27,355 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 0 | 20,539 | +20,539 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 0 | 15,720 | +15,720 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 13,600 | +13,600 | 0.00 | 0.00 | +0.00 | buy |
| Legacy Private Trust Co. | 0 | 10,000 | +10,000 | 0.00 | 0.01 | +0.01 | buy |
| MetLife Investment Management, LLC | 0 | 8,487 | +8,487 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 0 | 8,007 | +8,007 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN INTERNATIONAL GROUP, INC. | 0 | 7,394 | +7,394 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | 6,900 | +6,900 | 0.00 | 0.00 | +0.00 | buy |
| VIRTUS ADVISERS, LLC | 0 | 6,328 | +6,328 | 0.00 | 0.07 | +0.07 | buy |
| SG Americas Securities, LLC | 0 | 6,308 | +6,308 | 0.00 | 0.00 | +0.00 | buy |
| STRS OHIO | 0 | 3,200 | +3,200 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 2,558 | +2,558 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 0 | 2,449 | +2,449 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 0 | 1,709 | +1,709 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 0 | 1,540 | +1,540 | 0.00 | 0.00 | +0.00 | buy |
| METROPOLITAN LIFE INSURANCE CO/NY | 0 | 921 | +921 | 0.00 | 0.00 | +0.00 | buy |
| Advisory Services Network, LLC | 0 | 200 | +200 | 0.00 | 0.00 | +0.00 | buy |
| Quarry LP | 0 | 50 | +50 | 0.00 | 0.00 | +0.00 | buy |
| ORBIMED ADVISORS LLC | 1,500,000 | 1,500,000 | 0 | 0.45 | 0.51 | +0.06 | hold |
| SOFTBANK GROUP CORP. | 7,646,916 | 7,646,916 | 0 | 1.19 | 0.70 | -0.49 | hold |
| NORGES BANK | 50,000 | 50,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Ensign Peak Advisors, Inc | 150,000 | 150,000 | 0 | 0.00 | 0.01 | +0.00 | hold |
| Cormorant Asset Management, LP | 92,293 | 92,293 | 0 | 0.08 | 0.08 | -0.00 | hold |
| EcoR1 Capital, LLC | 2,071,450 | 2,071,450 | 0 | 1.00 | 0.92 | -0.08 | hold |
| HHLR ADVISORS, LTD. | 1,699,313 | 1,699,313 | 0 | 0.54 | 0.58 | +0.05 | hold |
| Ghisallo Capital Management LLC | 10,000 | 10,000 | 0 | 0.01 | 0.02 | +0.00 | hold |
| MIC Capital Management UK LLP | 4,460,700 | 4,460,700 | 0 | 14.35 | 14.76 | +0.41 | hold |
| WELLCOME TRUST LTD (THE) as trustee of the WELLCOME TRUST | 3,309,124 | 3,309,123 | -1 | 0.62 | 0.70 | +0.08 | sell |
| SALEM INVESTMENT COUNSELORS INC | 100 | 0 | -100 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 10,000 | 1,422 | -8,578 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 14,416 | 5,746 | -8,670 | 0.00 | 0.00 | -0.00 | sell |
| SOROS FUND MANAGEMENT LLC | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| Zimmer Partners, LP | 12,500 | 0 | -12,500 | 0.00 | 0.00 | -0.00 | sell |
| ROYAL BANK OF CANADA | 20,078 | 0 | -20,078 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 21,400 | 0 | -21,400 | 0.00 | 0.00 | -0.00 | sell |
| Laurion Capital Management LP | 21,557 | 0 | -21,557 | 0.01 | 0.00 | -0.01 | sell |
| SCOGGIN MANAGEMENT LP | 150,000 | 125,000 | -25,000 | 2.86 | 2.30 | -0.55 | sell |
| FIRST TRUST ADVISORS LP | 26,770 | 0 | -26,770 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 28,834 | 0 | -28,834 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Middle East FZE | 43,713 | 0 | -43,713 | 0.04 | 0.00 | -0.04 | sell |
| Greenland Capital Management LP | 47,613 | 0 | -47,613 | 0.08 | 0.00 | -0.08 | sell |
| TWO SIGMA INVESTMENTS, LP | 58,500 | 0 | -58,500 | 0.00 | 0.00 | -0.00 | sell |
| Artal Group S.A. | 2,802,702 | 2,552,702 | -250,000 | 1.72 | 1.48 | -0.24 | sell |
| MARSHALL WACE, LLP | 256,412 | 0 | -256,412 | 0.01 | 0.00 | -0.01 | sell |
| MILLENNIUM MANAGEMENT LLC | 274,748 | 0 | -274,748 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 2,168,518 | 1,843,291 | -325,227 | 0.03 | 0.03 | -0.00 | sell |
| SOROS CAPITAL MANAGEMENT LLC | 588,235 | 0 | -588,235 | 4.16 | 0.00 | -4.16 | sell |