| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| DEERFIELD MANAGEMENT COMPANY, L.P. | 304,013 | 357,199 | +53,186 | 0.57 | 0.57 | +0.00 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 357,650 | 390,829 | +33,179 | 0.94 | 0.80 | -0.14 | buy |
| HighVista Strategies LLC | 8,033 | 9,554 | +1,521 | 0.35 | 0.34 | -0.02 | buy |
| E Fund Management (Hong Kong) Co., Ltd. | 83 | 113 | +30 | 0.01 | 0.01 | -0.00 | buy |
| Voleon Capital Management LP | 7,883 | 6,289 | -1,594 | 0.03 | 0.02 | -0.01 | sell |
| PFM Health Sciences, LP | 59,432 | 34,803 | -24,629 | 0.86 | 0.46 | -0.40 | sell |