| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RTW INVESTMENTS, LP | 312,500 | 715,332 | +402,832 | 0.28 | 1.15 | +0.86 | buy |
| PERCEPTIVE ADVISORS LLC | 49,788 | 414,239 | +364,451 | 0.11 | 1.18 | +1.07 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 195,312 | 383,091 | +187,779 | 0.24 | 0.96 | +0.72 | buy |
| Virtus Investment Advisers, LLC | 1,831 | 1,882 | +51 | 0.04 | 0.08 | +0.04 | buy |
| China Universal Asset Management Co., Ltd. | 5,000 | 500 | -4,500 | 0.03 | 0.01 | -0.02 | sell |
| Soleus Capital Management, L.P. | 210,000 | 40,354 | -169,646 | 0.83 | 0.27 | -0.56 | sell |
| RA CAPITAL MANAGEMENT, L.P. | 875,000 | 432,484 | -442,516 | 0.80 | 0.71 | -0.09 | sell |