| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| EVENTIDE ASSET MANAGEMENT, LLC | 0 | 3,002,831 | +3,002,831 | 0.00 | 0.66 | +0.66 | buy |
| D1 Capital Partners L.P. | 0 | 2,506,607 | +2,506,607 | 0.00 | 0.59 | +0.59 | buy |
| JANUS HENDERSON GROUP PLC | 0 | 2,330,738 | +2,330,738 | 0.00 | 0.02 | +0.02 | buy |
| Omega Fund Management, LLC | 0 | 2,157,623 | +2,157,623 | 0.00 | 23.46 | +23.46 | buy |
| CITADEL ADVISORS LLC | 0 | 2,084,245 | +2,084,245 | 0.00 | 0.03 | +0.03 | buy |
| Novo Holdings A/S | 0 | 1,307,829 | +1,307,829 | 0.00 | 1.08 | +1.08 | buy |
| Blackstone Inc. | 0 | 696,110 | +696,110 | 0.00 | 0.04 | +0.04 | buy |
| Artal Group S.A. | 0 | 603,435 | +603,435 | 0.00 | 0.28 | +0.28 | buy |
| VANGUARD GROUP INC | 0 | 416,182 | +416,182 | 0.00 | 0.00 | +0.00 | buy |
| Laurion Capital Management LP | 0 | 255,301 | +255,301 | 0.00 | 0.12 | +0.12 | buy |
| Verition Fund Management LLC | 0 | 189,062 | +189,062 | 0.00 | 0.03 | +0.03 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 0 | 100,421 | +100,421 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 91,889 | +91,889 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 44,100 | +44,100 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 38,960 | +38,960 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 34,172 | +34,172 | 0.00 | 0.01 | +0.01 | buy |
| Point72 Middle East FZE | 0 | 28,578 | +28,578 | 0.00 | 0.03 | +0.03 | buy |
| Cubist Systematic Strategies, LLC | 0 | 25,750 | +25,750 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 0 | 15,589 | +15,589 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 0 | 15,517 | +15,517 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 0 | 15,000 | +15,000 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 0 | 14,110 | +14,110 | 0.00 | 0.00 | +0.00 | buy |
| CAXTON CORP | 0 | 10,319 | +10,319 | 0.00 | 0.75 | +0.75 | buy |
| Tower Research Capital LLC (TRC) | 0 | 1,490 | +1,490 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 603 | +603 | 0.00 | 0.00 | +0.00 | buy |
| Steward Partners Investment Advisory, LLC | 0 | 323 | +323 | 0.00 | 0.00 | +0.00 | buy |