| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Blue Owl Capital Holdings LP | 0 | 568,379 | +568,379 | 0.00 | 1.17 | +1.17 | buy |
| MORGAN STANLEY | 134,672 | 535,518 | +400,846 | 0.00 | 0.00 | +0.00 | buy |
| SPHERA FUNDS MANAGEMENT LTD. | 455,400 | 743,591 | +288,191 | 1.04 | 1.19 | +0.15 | buy |
| AMERICAN CENTURY COMPANIES INC | 419,676 | 679,261 | +259,585 | 0.00 | 0.00 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 450,017 | 699,467 | +249,450 | 0.00 | 0.00 | +0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0 | 186,168 | +186,168 | 0.00 | 0.05 | +0.05 | buy |
| Laurion Capital Management LP | 969,978 | 1,156,068 | +186,090 | 0.24 | 0.36 | +0.12 | buy |
| CITADEL ADVISORS LLC | 18,616 | 115,303 | +96,687 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 299,963 | 376,322 | +76,359 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 229,977 | 282,084 | +52,107 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 0 | 48,755 | +48,755 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 0 | 45,585 | +45,585 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 15,255 | 55,971 | +40,716 | 0.00 | 0.01 | +0.00 | buy |
| VANGUARD GROUP INC | 937,638 | 977,980 | +40,342 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 111,915 | 149,780 | +37,865 | 0.00 | 0.00 | +0.00 | buy |
| Pale Fire Capital SE | 0 | 34,743 | +34,743 | 0.00 | 0.05 | +0.05 | buy |
| TWO SIGMA INVESTMENTS, LP | 36,103 | 64,723 | +28,620 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 2,454 | 26,774 | +24,320 | 0.00 | 0.00 | +0.00 | buy |
| NEOS Investment Management LLC | 0 | 23,973 | +23,973 | 0.00 | 0.02 | +0.02 | buy |
| JPMORGAN CHASE & CO | 0 | 23,563 | +23,563 | 0.00 | 0.00 | +0.00 | buy |
| CORNERCAP INVESTMENT COUNSEL INC | 0 | 22,209 | +22,209 | 0.00 | 0.03 | +0.03 | buy |
| Cubist Systematic Strategies, LLC | 485 | 17,397 | +16,912 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 364,343 | 380,759 | +16,416 | 0.00 | 0.00 | -0.00 | buy |
| DAFNA Capital Management LLC | 0 | 15,200 | +15,200 | 0.00 | 0.03 | +0.03 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 106,406 | 120,872 | +14,466 | 0.00 | 0.00 | -0.00 | buy |
| UBS Group AG | 7,501 | 21,600 | +14,099 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0 | 11,514 | +11,514 | 0.00 | 0.00 | +0.00 | buy |
| CreativeOne Wealth, LLC | 0 | 10,750 | +10,750 | 0.00 | 0.01 | +0.01 | buy |
| SG Americas Securities, LLC | 0 | 10,093 | +10,093 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 40,428 | 46,932 | +6,504 | 0.00 | 0.00 | -0.00 | buy |
| VIRTUS ADVISERS, LLC | 6,205 | 11,222 | +5,017 | 0.04 | 0.06 | +0.03 | buy |
| China Universal Asset Management Co., Ltd. | 0 | 4,750 | +4,750 | 0.00 | 0.01 | +0.01 | buy |
| MetLife Investment Management, LLC | 7,063 | 11,416 | +4,353 | 0.00 | 0.00 | +0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 0 | 4,122 | +4,122 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 6 | 3,811 | +3,805 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 17,174 | 20,469 | +3,295 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 2,678 | 5,891 | +3,213 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 4,935 | 8,018 | +3,083 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN INTERNATIONAL GROUP, INC. | 6,964 | 9,656 | +2,692 | 0.00 | 0.00 | -0.00 | buy |
| METROPOLITAN LIFE INSURANCE CO/NY | 727 | 1,238 | +511 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 1,193 | 1,682 | +489 | 0.00 | 0.00 | +0.00 | buy |
| Glassman Wealth Services | 0 | 372 | +372 | 0.00 | 0.00 | +0.00 | buy |
| MassMutual Private Wealth & Trust, FSB | 0 | 319 | +319 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 463 | 724 | +261 | 0.00 | 0.00 | +0.00 | buy |
| COMERICA BANK | 513 | 690 | +177 | 0.00 | 0.00 | +0.00 | buy |
| Parallel Advisors, LLC | 0 | 159 | +159 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Middle East FZE | 0 | 135 | +135 | 0.00 | 0.00 | +0.00 | buy |
| QUADRANT CAPITAL GROUP LLC | 0 | 129 | +129 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,079 | 3,197 | +118 | 0.00 | 0.00 | -0.00 | buy |
| Avion Wealth | 0 | 78 | +78 | 0.00 | 0.00 | +0.00 | buy |
| Versant Capital Management, Inc | 0 | 63 | +63 | 0.00 | 0.00 | +0.00 | buy |
| Farther Finance Advisors, LLC | 0 | 17 | +17 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 972 | 972 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 15,860 | 15,860 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ADAMS STREET PARTNERS LLC | 2,302,329 | 2,302,329 | 0 | 7.65 | 6.10 | -1.55 | hold |
| LETKO, BROSSEAU & ASSOCIATES INC | 11,400 | 11,400 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RA CAPITAL MANAGEMENT, L.P. | 3,178,476 | 3,178,476 | 0 | 0.60 | 0.43 | -0.17 | hold |
| Alyeska Investment Group, L.P. | 37,500 | 37,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ensign Peak Advisors, Inc | 125,000 | 125,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PDT Partners, LLC | 13,912 | 13,912 | 0 | 0.02 | 0.01 | -0.00 | hold |
| Rock Springs Capital Management LP | 1,167,492 | 1,167,492 | 0 | 0.30 | 0.25 | -0.05 | hold |
| Samsara BioCapital, LLC | 4,519,361 | 4,519,361 | 0 | 13.16 | 6.05 | -7.11 | hold |
| Woodline Partners LP | 175,000 | 175,000 | 0 | 0.02 | 0.02 | -0.00 | hold |
| SR ONE CAPITAL MANAGEMENT, LP | 1,794,600 | 1,794,600 | 0 | 8.75 | 6.48 | -2.27 | hold |
| BRAIDWELL LP | 2,023,900 | 2,023,900 | 0 | 0.61 | 0.64 | +0.03 | hold |
| STRS OHIO | 2,500 | 2,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 3,545 | 3,513 | -32 | 0.00 | 0.00 | -0.00 | sell |
| AMALGAMATED BANK | 1,891 | 1,742 | -149 | 0.00 | 0.00 | -0.00 | sell |
| HUNTINGTON NATIONAL BANK | 166 | 0 | -166 | 0.00 | 0.00 | -0.00 | sell |
| UMB Bank, n.a. | 1,046 | 0 | -1,046 | 0.00 | 0.00 | -0.00 | sell |
| Riverview Trust Co | 1,353 | 0 | -1,353 | 0.01 | 0.00 | -0.01 | sell |
| Allspring Global Investments Holdings, LLC | 1,663 | 0 | -1,663 | 0.00 | 0.00 | -0.00 | sell |
| FEDERATED HERMES, INC. | 22,293 | 20,032 | -2,261 | 0.00 | 0.00 | -0.00 | sell |
| ALPS ADVISORS INC | 30,148 | 26,675 | -3,473 | 0.00 | 0.00 | -0.00 | sell |
| Russell Investments Group, Ltd. | 10,180 | 5,779 | -4,401 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 5,678 | 0 | -5,678 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 10,060 | 2,879 | -7,181 | 0.00 | 0.00 | -0.00 | sell |
| Ghisallo Capital Management LLC | 10,000 | 0 | -10,000 | 0.01 | 0.00 | -0.01 | sell |
| Jump Financial, LLC | 32,700 | 20,500 | -12,200 | 0.01 | 0.01 | -0.01 | sell |
| XTX Topco Ltd | 18,670 | 0 | -18,670 | 0.03 | 0.00 | -0.03 | sell |
| OCCUDO QUANTITATIVE STRATEGIES LP | 22,489 | 0 | -22,489 | 0.03 | 0.00 | -0.03 | sell |
| Point72 Asset Management, L.P. | 163,185 | 129,900 | -33,285 | 0.01 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 43,057 | 0 | -43,057 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 95,690 | 25,500 | -70,190 | 0.00 | 0.00 | -0.00 | sell |
| ExodusPoint Capital Management, LP | 159,441 | 73,940 | -85,501 | 0.02 | 0.01 | -0.01 | sell |
| Schonfeld Strategic Advisors LLC | 192,362 | 0 | -192,362 | 0.02 | 0.00 | -0.02 | sell |
| SECTORAL ASSET MANAGEMENT INC | 840,759 | 605,606 | -235,153 | 1.56 | 2.24 | +0.69 | sell |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 501,374 | 206,265 | -295,109 | 0.06 | 0.02 | -0.04 | sell |
| JANUS HENDERSON GROUP PLC | 665,717 | 0 | -665,717 | 0.00 | 0.00 | -0.00 | sell |
| RTW INVESTMENTS, LP | 922,100 | 0 | -922,100 | 0.19 | 0.00 | -0.19 | sell |
| FMR LLC | 1,188,653 | 31,287 | -1,157,366 | 0.00 | 0.00 | -0.00 | sell |