| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) | Type |
|---|---|---|---|---|---|---|---|
| Rubric Capital Management LP | 5,750,000 | 7,000,000 | +1,250,000 | 1.81 | 2.15 | +0.34 | buy |
| PERCEPTIVE ADVISORS LLC | 3,261,850 | 3,510,078 | +248,228 | 1.57 | 1.74 | +0.16 | buy |
| Hillsdale Investment Management Inc. | 237,922 | 345,622 | +107,700 | 0.17 | 0.24 | +0.06 | buy |
| SummitTX Capital, L.P. | 224,268 | 321,427 | +97,159 | 0.18 | 0.26 | +0.08 | buy |
| Granahan Investment Management, LLC | 224,408 | 250,773 | +26,365 | 0.25 | 0.30 | +0.05 | buy |
| Prosight Management, LP | 530,393 | 539,049 | +8,656 | 2.89 | 2.21 | -0.67 | buy |
| Dana Investment Advisors, Inc. | 48,318 | 56,107 | +7,789 | 0.04 | 0.04 | +0.00 | buy |
| North Growth Management Ltd. | 45,000 | 46,000 | +1,000 | 0.19 | 0.17 | -0.01 | buy |
| HighMark Wealth Management LLC | 230 | 80 | -150 | 0.00 | 0.00 | -0.00 | sell |
| Capricorn Fund Managers Ltd | 1,022,840 | 1,007,210 | -15,630 | 6.49 | 3.93 | -2.56 | sell |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 181,790 | 163,649 | -18,141 | 0.03 | 0.03 | -0.00 | sell |
| Soleus Capital Management, L.P. | 100,000 | 10,000 | -90,000 | 0.11 | 0.01 | -0.10 | sell |
| BVF INC/IL | 3,938,641 | 3,734,142 | -204,499 | 3.49 | 2.98 | -0.51 | sell |