| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| CITADEL ADVISORS LLC | 162,319 | 993,620 | +831,301 | 0.00 | 0.00 | +0.00 | buy |
| Peapod Lane Capital LLC | 0 | 396,221 | +396,221 | 0.00 | 0.86 | +0.86 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 44,700 | 124,958 | +80,258 | 0.00 | 0.00 | +0.00 | buy |
| Insight Holdings Group, LLC | 912,915 | 989,054 | +76,139 | 0.22 | 0.15 | -0.07 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 71,057 | +71,057 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 80,000 | 136,300 | +56,300 | 0.01 | 0.01 | -0.00 | buy |
| SEI INVESTMENTS CO | 0 | 24,660 | +24,660 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 539,682 | 563,974 | +24,292 | 0.00 | 0.00 | -0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 43,762 | 67,546 | +23,784 | 0.01 | 0.01 | -0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 21,945 | +21,945 | 0.00 | 0.00 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 52,361 | 68,628 | +16,267 | 0.00 | 0.00 | -0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 0 | 15,275 | +15,275 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 0 | 13,552 | +13,552 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 0 | 12,275 | +12,275 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 15,241 | 24,561 | +9,320 | 0.00 | 0.00 | -0.00 | buy |
| SUPERSTRING CAPITAL MANAGEMENT LP | 182,177 | 191,287 | +9,110 | 0.60 | 0.44 | -0.16 | buy |
| Bank of New York Mellon Corp | 39,933 | 48,784 | +8,851 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 25,920 | 31,614 | +5,694 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 2,742 | 8,173 | +5,431 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 229 | 5,482 | +5,253 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 1,464 | 6,214 | +4,750 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 32,000 | 36,000 | +4,000 | 0.00 | 0.00 | -0.00 | buy |
| BlackRock, Inc. | 1,672,493 | 1,676,268 | +3,775 | 0.00 | 0.00 | -0.00 | buy |
| Point72 (DIFC) Ltd | 0 | 2,084 | +2,084 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 0 | 1,827 | +1,827 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 44,983 | 46,381 | +1,398 | 0.00 | 0.00 | -0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 37,794 | 38,602 | +808 | 0.00 | 0.00 | -0.00 | buy |
| FMR LLC | 1,609 | 2,393 | +784 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 14,288 | 14,912 | +624 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA ADVISERS, LP | 80,290 | 80,900 | +610 | 0.00 | 0.00 | -0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 515 | +515 | 0.00 | 0.00 | +0.00 | buy |
| Physician Wealth Advisors, Inc. | 0 | 420 | +420 | 0.00 | 0.00 | +0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 906 | 1,070 | +164 | 0.00 | 0.00 | -0.00 | buy |
| True Wealth Design, LLC | 0 | 154 | +154 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 0 | 81 | +81 | 0.00 | 0.00 | +0.00 | buy |
| Kera Capital Partners, Inc. | 376,131 | 376,186 | +55 | 0.40 | 0.22 | -0.19 | buy |
| Mirae Asset Global Investments Co., Ltd. | 1,439 | 1,445 | +6 | 0.00 | 0.00 | -0.00 | buy |
| Ameritas Investment Partners, Inc. | 1,649 | 1,649 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TD ASSET MANAGEMENT INC | 90,242 | 90,242 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 1,932 | 1,932 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 30,010 | 30,010 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Novo Holdings A/S | 1,850,000 | 1,850,000 | 0 | 0.42 | 0.27 | -0.15 | hold |
| CAXTON CORP | 22,981 | 22,981 | 0 | 0.52 | 0.87 | +0.36 | hold |
| DekaBank Deutsche Girozentrale | 7,500 | 7,500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| IFP Advisors, Inc | 2 | 2 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Bain Capital Life Sciences Investors, LLC | 3,368,370 | 3,368,370 | 0 | 1.48 | 0.96 | -0.52 | hold |
| Vida Ventures Advisors, LLC | 4,523,924 | 4,523,924 | 0 | 11.56 | 64.02 | +52.46 | hold |
| SBI Securities Co., Ltd. | 140 | 140 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MBB PUBLIC MARKETS I LLC | 614,477 | 614,477 | 0 | 0.27 | 0.14 | -0.14 | hold |
| Catalio Capital Management, LP | 586,909 | 586,909 | 0 | 0.48 | 0.28 | -0.20 | hold |
| Police & Firemen's Retirement System of New Jersey | 3,385 | 3,385 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Fourth Dimension Wealth, LLC | 250 | 250 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FRANKLIN RESOURCES INC | 692,028 | 692,028 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Legal & General Group Plc | 2,769 | 2,769 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 4,500 | 4,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STRS OHIO | 3,100 | 3,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GILEAD SCIENCES, INC. | 4,126,119 | 4,126,119 | 0 | 0.99 | 0.67 | -0.32 | hold |
| AMALGAMATED BANK | 582 | 582 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Sterling Capital Management LLC | 233 | 186 | -47 | 0.00 | 0.00 | -0.00 | sell |
| ROTHSCHILD INVESTMENT LLC | 105 | 50 | -55 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 364 | 259 | -105 | 0.00 | 0.00 | -0.00 | sell |
| STIFEL FINANCIAL CORP | 39,342 | 39,163 | -179 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 12,811 | 12,624 | -187 | 0.00 | 0.00 | -0.00 | sell |
| R Squared Ltd | 240 | 0 | -240 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 9,154 | 8,659 | -495 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 20,325 | 19,153 | -1,172 | 0.00 | 0.00 | -0.00 | sell |
| ALPS ADVISORS INC | 34,912 | 32,126 | -2,786 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 3,765 | 0 | -3,765 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 195,694 | 191,664 | -4,030 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 4,171 | 0 | -4,171 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 169,780 | 165,370 | -4,410 | 0.00 | 0.00 | -0.00 | sell |
| US BANCORP \DE\ | 4,600 | 0 | -4,600 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 379,888 | 374,578 | -5,310 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 89,586 | 81,390 | -8,196 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 113,474 | 104,460 | -9,014 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 11,488 | 0 | -11,488 | 0.00 | 0.00 | -0.00 | sell |
| Corton Capital Inc. | 12,099 | 0 | -12,099 | 0.03 | 0.00 | -0.03 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 593,688 | 579,604 | -14,084 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 1,313,232 | 1,298,449 | -14,783 | 0.00 | 0.00 | -0.00 | sell |
| UBS Group AG | 203,403 | 177,670 | -25,733 | 0.00 | 0.00 | -0.00 | sell |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 33,434 | 1,098 | -32,336 | 0.00 | 0.00 | -0.00 | sell |
| NORGES BANK | 40,000 | 0 | -40,000 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 43,949 | 0 | -43,949 | 0.01 | 0.00 | -0.01 | sell |
| Alyeska Investment Group, L.P. | 45,000 | 0 | -45,000 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 181,654 | 122,977 | -58,677 | 0.00 | 0.00 | -0.00 | sell |
| Verition Fund Management LLC | 90,235 | 0 | -90,235 | 0.00 | 0.00 | -0.00 | sell |
| SPHERA FUNDS MANAGEMENT LTD. | 118,758 | 0 | -118,758 | 0.08 | 0.00 | -0.08 | sell |
| Rock Springs Capital Management LP | 178,963 | 0 | -178,963 | 0.03 | 0.00 | -0.03 | sell |
| WELLS FARGO & COMPANY/MN | 179,012 | 0 | -179,012 | 0.00 | 0.00 | -0.00 | sell |
| AMERIPRISE FINANCIAL INC | 190,383 | 0 | -190,383 | 0.00 | 0.00 | -0.00 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 274,414 | 37,828 | -236,586 | 0.00 | 0.00 | -0.00 | sell |
| Integral Health Asset Management, LLC | 350,000 | 0 | -350,000 | 0.12 | 0.00 | -0.12 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 461,959 | 0 | -461,959 | 0.01 | 0.00 | -0.01 | sell |
| MILLENNIUM MANAGEMENT LLC | 746,521 | 238,239 | -508,282 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 2,166,437 | 39,502 | -2,126,935 | 0.00 | 0.00 | -0.00 | sell |