| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Alpha Wave Global, LP | 3,707,757 | 3,707,757 | 0 | 8.09 | 10.54 | +2.45 | hold |
| Commodore Capital LP | 1,823,196 | 2,723,196 | +900,000 | 2.16 | 3.54 | +1.38 | buy |
| Vestal Point Capital, LP | 2,485,000 | 2,064,075 | -420,925 | 1.62 | 1.30 | -0.33 | sell |
| PERCEPTIVE ADVISORS LLC | 1,784,393 | 2,009,893 | +225,500 | 0.58 | 0.89 | +0.31 | buy |
| FRANKLIN RESOURCES INC | 1,119,578 | 1,101,874 | -17,704 | 0.00 | 0.01 | +0.00 | sell |
| Vivo Capital, LLC | 1,035,551 | 1,035,551 | 0 | 1.19 | 1.94 | +0.74 | hold |
| ARMISTICE CAPITAL, LLC | 1,536,000 | 912,000 | -624,000 | 0.67 | 0.68 | +0.01 | sell |
| MILLENNIUM MANAGEMENT LLC | 629,985 | 821,982 | +191,997 | 0.01 | 0.01 | +0.01 | buy |
| 72 Investment Holdings, LLC | 667,778 | 667,778 | 0 | 23.50 | 30.26 | +6.76 | hold |
| BlackRock, Inc. | 607,874 | 666,188 | +58,314 | 0.00 | 0.00 | +0.00 | buy |
| Ikarian Capital, LLC | 515,000 | 515,000 | 0 | 1.19 | 1.66 | +0.47 | hold |
| Point72 Asset Management, L.P. | 1,606,954 | 503,087 | -1,103,867 | 0.04 | 0.02 | -0.03 | sell |
| VR Adviser, LLC | 0 | 500,000 | +500,000 | 0.00 | 0.42 | +0.42 | buy |
| Affinity Asset Advisors, LLC | 0 | 500,000 | +500,000 | 0.00 | 0.66 | +0.66 | buy |
| Integral Health Asset Management, LLC | 375,000 | 500,000 | +125,000 | 0.34 | 0.59 | +0.26 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 336,762 | 486,726 | +149,964 | 0.04 | 0.08 | +0.04 | buy |
| NORTHERN TRUST CORP | 474,373 | 473,403 | -970 | 0.00 | 0.00 | +0.00 | sell |
| JENNISON ASSOCIATES LLC | 0 | 386,426 | +386,426 | 0.00 | 0.01 | +0.01 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 0 | 385,000 | +385,000 | 0.00 | 0.01 | +0.01 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 30,228 | 371,208 | +340,980 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 287,435 | 292,899 | +5,464 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 118,156 | 238,498 | +120,342 | 0.00 | 0.01 | +0.00 | buy |
| ALKEON CAPITAL MANAGEMENT LLC | 477,101 | 227,101 | -250,000 | 0.04 | 0.02 | -0.01 | sell |
| TWO SIGMA INVESTMENTS, LP | 140,317 | 216,099 | +75,782 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 112,792 | 209,268 | +96,476 | 0.00 | 0.01 | +0.00 | buy |
| STATE STREET CORP | 130,665 | 199,503 | +68,838 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 193,109 | 176,347 | -16,762 | 0.00 | 0.00 | +0.00 | sell |
| AWM Investment Company, Inc. | 225,000 | 170,000 | -55,000 | 0.39 | 0.42 | +0.04 | sell |
| ORBIMED ADVISORS LLC | 125,000 | 167,500 | +42,500 | 0.05 | 0.08 | +0.04 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 139,304 | 139,304 | 0 | 0.06 | 0.07 | +0.01 | hold |
| Eversept Partners, LP | 0 | 125,168 | +125,168 | 0.00 | 0.19 | +0.19 | buy |
| GOLDMAN SACHS GROUP INC | 156,319 | 104,717 | -51,602 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 97,399 | 103,499 | +6,100 | 0.00 | 0.00 | +0.00 | buy |
| Saturn V Capital Management LP | 0 | 88,999 | +88,999 | 0.00 | 0.36 | +0.36 | buy |
| STIFEL FINANCIAL CORP | 87,164 | 86,335 | -829 | 0.00 | 0.00 | +0.00 | sell |
| Almitas Capital LLC | 78,520 | 78,520 | 0 | 0.31 | 0.40 | +0.09 | hold |
| MORGAN STANLEY | 0 | 68,654 | +68,654 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 57,546 | 60,076 | +2,530 | 0.00 | 0.00 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 69,016 | 59,799 | -9,217 | 0.00 | 0.00 | +0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 77,653 | 52,653 | -25,000 | 0.03 | 0.02 | -0.01 | sell |
| D. E. Shaw & Co., Inc. | 124,795 | 45,343 | -79,452 | 0.00 | 0.00 | -0.00 | sell |
| TD ASSET MANAGEMENT INC | 0 | 43,800 | +43,800 | 0.00 | 0.00 | +0.00 | buy |
| Hudson Bay Capital Management LP | 34,789 | 43,762 | +8,973 | 0.00 | 0.01 | +0.00 | buy |
| AdvisorShares Investments LLC | 44,077 | 41,023 | -3,054 | 0.13 | 0.17 | +0.04 | sell |
| 683 Capital Management, LLC | 64,782 | 40,000 | -24,782 | 0.10 | 0.08 | -0.01 | sell |
| XTX Topco Ltd | 20,824 | 39,841 | +19,017 | 0.01 | 0.02 | +0.01 | buy |
| DIMENSIONAL FUND ADVISORS LP | 31,176 | 39,324 | +8,148 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 0 | 38,782 | +38,782 | 0.00 | 0.01 | +0.01 | buy |
| Quantinno Capital Management LP | 35,579 | 36,069 | +490 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 11,120 | 32,111 | +20,991 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 194,041 | 30,058 | -163,983 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 0 | 29,961 | +29,961 | 0.00 | 0.00 | +0.00 | buy |
| Allianz Asset Management GmbH | 43,000 | 28,500 | -14,500 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 0 | 25,677 | +25,677 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 25,505 | 25,288 | -217 | 0.00 | 0.00 | +0.00 | sell |
| BARCLAYS PLC | 30,392 | 25,036 | -5,356 | 0.00 | 0.00 | -0.00 | sell |
| BROWN ADVISORY INC | 25,000 | 25,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Y-Intercept (Hong Kong) Ltd | 0 | 23,945 | +23,945 | 0.00 | 0.01 | +0.01 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0 | 23,747 | +23,747 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 75,294 | 23,727 | -51,567 | 0.00 | 0.00 | -0.00 | sell |
| UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 22,175 | 22,175 | 0 | 0.06 | 0.07 | +0.02 | hold |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 0 | 18,083 | +18,083 | 0.00 | 0.03 | +0.03 | buy |
| Revisor Wealth Management LLC | 0 | 17,130 | +17,130 | 0.00 | 0.11 | +0.11 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 17,064 | 17,018 | -46 | 0.00 | 0.00 | +0.00 | sell |
| SCS Capital Management LLC | 33,389 | 16,840 | -16,549 | 0.01 | 0.00 | -0.00 | sell |
| POLEN CAPITAL MANAGEMENT LLC | 0 | 16,613 | +16,613 | 0.00 | 0.00 | +0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 16,485 | 15,646 | -839 | 0.00 | 0.00 | +0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 10,360 | 14,186 | +3,826 | 0.00 | 0.00 | +0.00 | buy |
| TORONTO DOMINION BANK | 0 | 13,434 | +13,434 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 13,487 | 13,324 | -163 | 0.00 | 0.00 | +0.00 | sell |
| Clearstead Advisors, LLC | 0 | 13,312 | +13,312 | 0.00 | 0.00 | +0.00 | buy |
| Catalyst Funds Management Pty Ltd | 0 | 11,400 | +11,400 | 0.00 | 0.04 | +0.04 | buy |
| BANK OF MONTREAL /CAN/ | 11,355 | 11,343 | -12 | 0.00 | 0.00 | +0.00 | sell |
| Diametric Capital, LP | 0 | 10,315 | +10,315 | 0.00 | 0.06 | +0.06 | buy |
| OMERS ADMINISTRATION Corp | 12,400 | 9,700 | -2,700 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 12,566 | 9,430 | -3,136 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 6,374 | 6,314 | -60 | 0.00 | 0.00 | +0.00 | sell |
| WHITTIER TRUST CO OF NEVADA INC | 2,482 | 2,482 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ROTHSCHILD INVESTMENT LLC | 2,885 | 1,685 | -1,200 | 0.00 | 0.00 | -0.00 | sell |
| PNC FINANCIAL SERVICES GROUP, INC. | 1,307 | 1,206 | -101 | 0.00 | 0.00 | +0.00 | sell |
| Advisory Services Network, LLC | 0 | 802 | +802 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 770 | 654 | -116 | 0.00 | 0.00 | +0.00 | sell |
| EverSource Wealth Advisors, LLC | 661 | 628 | -33 | 0.00 | 0.00 | -0.00 | sell |
| JONES FINANCIAL COMPANIES LLLP | 0 | 533 | +533 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 450 | +450 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 1,413 | 400 | -1,013 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 338 | 338 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 33,235 | 314 | -32,921 | 0.00 | 0.00 | -0.00 | sell |
| Russell Investments Group, Ltd. | 306 | 306 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Accent Capital Management, LLC | 0 | 275 | +275 | 0.00 | 0.00 | +0.00 | buy |
| US BANCORP \DE\ | 113 | 110 | -3 | 0.00 | 0.00 | +0.00 | sell |
| Tower Research Capital LLC (TRC) | 1,987 | 65 | -1,922 | 0.00 | 0.00 | -0.00 | sell |
| SIGNATUREFD, LLC | 1,065 | 41 | -1,024 | 0.00 | 0.00 | -0.00 | sell |
| SBI Securities Co., Ltd. | 12 | 12 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Arax Advisory Partners | 5 | 5 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Optiver Holding B.V. | 20 | 4 | -16 | 0.00 | 0.00 | -0.00 | sell |
| North Star Investment Management Corp. | 174 | 0 | -174 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 12,973 | 0 | -12,973 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 160,100 | 0 | -160,100 | 0.01 | 0.00 | -0.01 | sell |
| CWM, LLC | 154 | 0 | -154 | 0.00 | 0.00 | -0.00 | sell |