| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ALKEON CAPITAL MANAGEMENT LLC | 0 | 934,904 | +934,904 | 0.00 | 0.05 | +0.05 | buy |
| RA CAPITAL MANAGEMENT, L.P. | 1,385,491 | 2,085,554 | +700,063 | 0.27 | 0.29 | +0.02 | buy |
| Vestal Point Capital, LP | 250,000 | 620,000 | +370,000 | 0.32 | 0.49 | +0.18 | buy |
| ExodusPoint Capital Management, LP | 606,730 | 836,093 | +229,363 | 0.12 | 0.10 | -0.02 | buy |
| DAFNA Capital Management LLC | 10,000 | 120,000 | +110,000 | 0.03 | 0.31 | +0.27 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 86,141 | 188,970 | +102,829 | 0.00 | 0.00 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 0 | 86,792 | +86,792 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 25,400 | 105,872 | +80,472 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 536,332 | 586,518 | +50,186 | 0.00 | 0.00 | -0.00 | buy |
| NORGES BANK | 28,873 | 76,672 | +47,799 | 0.00 | 0.00 | +0.00 | buy |
| Bowie Capital Management, LLC | 0 | 43,186 | +43,186 | 0.00 | 0.03 | +0.03 | buy |
| Alyeska Investment Group, L.P. | 10,000 | 50,000 | +40,000 | 0.00 | 0.00 | +0.00 | buy |
| AWM Investment Company, Inc. | 299,147 | 329,231 | +30,084 | 0.60 | 0.48 | -0.13 | buy |
| Bank of New York Mellon Corp | 0 | 23,557 | +23,557 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 45,031 | 66,189 | +21,158 | 0.00 | 0.00 | -0.00 | buy |
| ALPS ADVISORS INC | 0 | 20,981 | +20,981 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 0 | 14,155 | +14,155 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 0 | 10,539 | +10,539 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | 9,500 | +9,500 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 637,604 | 645,832 | +8,228 | 0.00 | 0.00 | -0.00 | buy |
| Philadelphia Financial Management of San Francisco, LLC | 435,489 | 443,289 | +7,800 | 1.40 | 1.10 | -0.29 | buy |
| NORTHERN TRUST CORP | 16,387 | 21,034 | +4,647 | 0.00 | 0.00 | -0.00 | buy |
| JENNISON ASSOCIATES LLC | 458,599 | 461,678 | +3,079 | 0.00 | 0.00 | -0.00 | buy |
| FEDERATED HERMES, INC. | 9,000 | 12,000 | +3,000 | 0.00 | 0.00 | -0.00 | buy |
| STRS OHIO | 0 | 1,600 | +1,600 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 0 | 894 | +894 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 0 | 869 | +869 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 0 | 643 | +643 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 600 | +600 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 0 | 307 | +307 | 0.00 | 0.00 | +0.00 | buy |
| Avior Wealth Management, LLC | 0 | 236 | +236 | 0.00 | 0.00 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 625,012 | 625,039 | +27 | 0.00 | 0.00 | -0.00 | buy |
| UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 22,175 | 22,175 | 0 | 0.08 | 0.05 | -0.03 | hold |
| Artal Group S.A. | 350,000 | 350,000 | 0 | 0.14 | 0.10 | -0.04 | hold |
| Alpha Wave Global, LP | 3,707,757 | 3,707,757 | 0 | 17.29 | 13.26 | -4.04 | hold |
| Woodline Partners LP | 125,000 | 125,000 | 0 | 0.02 | 0.01 | -0.00 | hold |
| WOLFF WIESE MAGANA LLC | 730 | 730 | 0 | 0.01 | 0.01 | -0.00 | hold |
| 72 Investment Holdings, LLC | 667,778 | 667,778 | 0 | 15.28 | 17.94 | +2.66 | hold |
| Valor Management LLC | 157,038 | 157,038 | 0 | 0.50 | 0.37 | -0.13 | hold |
| BIT Capital GmbH | 79,562 | 79,562 | 0 | 0.11 | 0.08 | -0.03 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 35,670 | 35,670 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Board of Trustees of The Leland Stanford Junior University | 344,015 | 344,013 | -2 | 0.46 | 0.25 | -0.21 | sell |
| MACQUARIE GROUP LTD | 473 | 0 | -473 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 1,046 | 0 | -1,046 | 0.00 | 0.00 | -0.00 | sell |
| FRED ALGER MANAGEMENT, LLC | 118,016 | 116,254 | -1,762 | 0.01 | 0.01 | -0.00 | sell |
| BARCLAYS PLC | 5,904 | 3,043 | -2,861 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 4,336 | 0 | -4,336 | 0.00 | 0.00 | -0.00 | sell |
| BLAIR WILLIAM & CO/IL | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| Diametric Capital, LP | 16,200 | 0 | -16,200 | 0.14 | 0.00 | -0.14 | sell |
| FMR LLC | 2,349,916 | 2,331,016 | -18,900 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 21,293 | 0 | -21,293 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 24,997 | 0 | -24,997 | 0.00 | 0.00 | -0.00 | sell |
| Lighthouse Investment Partners, LLC | 27,823 | 0 | -27,823 | 0.02 | 0.00 | -0.02 | sell |
| Squarepoint Ops LLC | 28,369 | 0 | -28,369 | 0.00 | 0.00 | -0.00 | sell |
| SPHERA FUNDS MANAGEMENT LTD. | 30,500 | 0 | -30,500 | 0.08 | 0.00 | -0.08 | sell |
| CITIGROUP INC | 33,842 | 1,953 | -31,889 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 33,059 | 0 | -33,059 | 0.00 | 0.00 | -0.00 | sell |
| Walleye Capital LLC | 50,000 | 0 | -50,000 | 0.01 | 0.00 | -0.01 | sell |
| Point72 Asset Management, L.P. | 1,125,000 | 1,050,037 | -74,963 | 0.05 | 0.04 | -0.01 | sell |
| Zimmer Partners, LP | 75,000 | 0 | -75,000 | 0.03 | 0.00 | -0.03 | sell |
| Deep Track Capital, LP | 600,000 | 511,686 | -88,314 | 0.26 | 0.16 | -0.10 | sell |
| MILLENNIUM MANAGEMENT LLC | 119,216 | 16,838 | -102,378 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 173,648 | 0 | -173,648 | 0.00 | 0.00 | -0.00 | sell |