| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 9,812,419 | 9,876,576 | +64,157 | 0.28 | 0.48 | +0.20 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 700,000 | 821,261 | +121,261 | 0.00 | 0.00 | +0.00 | buy |
| Shaolin Capital Management LLC | 260,000 | 616,160 | +356,160 | 0.01 | 0.01 | +0.00 | buy |
| RTW INVESTMENTS, LP | 209,361 | 209,361 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Opaleye Management Inc. | 110,571 | 110,571 | 0 | 0.02 | 0.03 | +0.01 | hold |
| Affinity Asset Advisors, LLC | 213,235 | 80,000 | -133,235 | 0.03 | 0.02 | -0.01 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 36,799 | 36,242 | -557 | 0.00 | 0.00 | +0.00 | sell |
| TORONTO DOMINION BANK | 30,875 | 25,000 | -5,875 | 0.00 | 0.00 | +0.00 | sell |
| Tower Research Capital LLC (TRC) | 2,670 | 3,474 | +804 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 11,435 | 0 | -11,435 | 0.00 | 0.00 | -0.00 | sell |
| ADAR1 Capital Management, LLC | 76,757 | 0 | -76,757 | 0.01 | 0.00 | -0.01 | sell |
| JPMORGAN CHASE & CO | 100,000 | 0 | -100,000 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 197 | 0 | -197 | 0.00 | 0.00 | -0.00 | sell |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |