| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 9,812,419 | 9,812,419 | 0 | 0.54 | 0.29 | -0.26 | hold |
| Affinity Asset Advisors, LLC | 213,235 | 213,235 | 0 | 0.09 | 0.03 | -0.05 | hold |
| RTW INVESTMENTS, LP | 209,361 | 209,361 | 0 | 0.01 | 0.00 | -0.00 | hold |
| Shaolin Capital Management LLC | 140,000 | 197,500 | +57,500 | 0.02 | 0.01 | -0.01 | buy |
| Opaleye Management Inc. | 110,571 | 110,571 | 0 | 0.05 | 0.02 | -0.03 | hold |
| JPMORGAN CHASE & CO | 0 | 100,000 | +100,000 | 0.00 | 0.00 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 148,861 | 76,757 | -72,104 | 0.06 | 0.02 | -0.05 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 23,107 | 22,752 | -355 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 0 | 21,180 | +21,180 | 0.00 | 0.00 | +0.00 | buy |
| TORONTO DOMINION BANK | 0 | 20,000 | +20,000 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 12,120 | +12,120 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 4,454 | +4,454 | 0.00 | 0.00 | +0.00 | buy |
| RA CAPITAL MANAGEMENT, L.P. | 1,333,926 | 0 | -1,333,926 | 0.04 | 0.00 | -0.04 | sell |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |