| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Woodline Partners LP | 0 | 358,436 | +358,436 | 0.00 | 0.03 | +0.03 | buy |
| PFM Health Sciences, LP | 135,546 | 439,283 | +303,737 | 0.16 | 0.47 | +0.31 | buy |
| Sofinnova Investments, Inc. | 527,190 | 697,916 | +170,726 | 0.60 | 0.74 | +0.14 | buy |
| HighTower Advisors, LLC | 781,752 | 871,754 | +90,002 | 0.02 | 0.02 | +0.00 | buy |
| Groupe la Francaise | 0 | 75,932 | +75,932 | 0.00 | 0.02 | +0.02 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 143,475 | 192,498 | +49,023 | 0.01 | 0.01 | +0.00 | buy |
| Tabor Asset Management, LP | 0 | 36,195 | +36,195 | 0.00 | 0.14 | +0.14 | buy |
| UBS Group AG | 0 | 27,468 | +27,468 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 0 | 18,667 | +18,667 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 16,918 | +16,918 | 0.00 | 0.01 | +0.01 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 255,133 | 260,029 | +4,896 | 0.00 | 0.00 | -0.00 | buy |
| GROUP ONE TRADING LLC | 144 | 3,627 | +3,483 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 51,445 | 52,800 | +1,355 | 0.00 | 0.00 | -0.00 | buy |
| BlackRock, Inc. | 831,807 | 832,732 | +925 | 0.00 | 0.00 | -0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 118 | 824 | +706 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 14,807 | 15,432 | +625 | 0.00 | 0.00 | -0.00 | buy |
| GAMMA Investing LLC | 69 | 490 | +421 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 116,104 | 116,513 | +409 | 0.00 | 0.00 | -0.00 | buy |
| Versant Capital Management, Inc | 0 | 396 | +396 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 6,653 | 6,965 | +312 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 6,647 | 6,781 | +134 | 0.00 | 0.00 | -0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 304 | 359 | +55 | 0.00 | 0.00 | +0.00 | buy |
| CoreCap Advisors, LLC | 0 | 18 | +18 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 3 | 10 | +7 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 482 | 488 | +6 | 0.00 | 0.00 | -0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 0 | 4 | +4 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 853 | 853 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 858 | 858 | 0 | 0.00 | 0.00 | -0.00 | hold |
| VIKING GLOBAL INVESTORS LP | 1,787,705 | 1,787,705 | 0 | 0.09 | 0.08 | -0.01 | hold |
| ALLIANCEBERNSTEIN L.P. | 17,930 | 17,930 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Sanofi | 1,157,926 | 1,157,926 | 0 | 10.23 | 9.76 | -0.47 | hold |
| PERCEPTIVE ADVISORS LLC | 1,064,026 | 1,064,026 | 0 | 0.46 | 0.53 | +0.07 | hold |
| CREDIT INDUSTRIEL ET COMMERCIAL | 64,217 | 64,217 | 0 | 0.26 | 0.16 | -0.10 | hold |
| NATIXIS | 2,000 | 2,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| JBF Capital, Inc. | 20,949 | 20,949 | 0 | 0.06 | 0.06 | +0.00 | hold |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 22,584 | 22,584 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Arbiter Partners Capital Management LLC | 28,095 | 28,095 | 0 | 0.64 | 0.48 | -0.16 | hold |
| MetLife Investment Management, LLC | 7,683 | 7,683 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BOOTHBAY FUND MANAGEMENT, LLC | 28,230 | 28,230 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Yakira Capital Management, Inc. | 36,195 | 36,195 | 0 | 0.22 | 0.21 | -0.02 | hold |
| Birchview Capital, LP | 32,110 | 32,110 | 0 | 0.40 | 0.39 | -0.01 | hold |
| IFP Advisors, Inc | 4 | 4 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Schonfeld Strategic Advisors LLC | 144,178 | 144,178 | 0 | 0.01 | 0.01 | -0.00 | hold |
| EverSource Wealth Advisors, LLC | 6 | 6 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FNY Investment Advisers, LLC | 250 | 250 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Meridian Wealth Advisors, LLC | 25,000 | 25,000 | 0 | 0.06 | 0.06 | -0.00 | hold |
| Ikarian Capital, LLC | 42,122 | 42,122 | 0 | 0.19 | 0.19 | +0.01 | hold |
| Murchinson Ltd. | 33,790 | 33,790 | 0 | 0.23 | 0.07 | -0.17 | hold |
| Farther Finance Advisors, LLC | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Police & Firemen's Retirement System of New Jersey | 3,374 | 3,374 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Legal & General Group Plc | 1,045 | 1,045 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 3,472 | 3,472 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STRS OHIO | 1,900 | 1,900 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 32,657 | 32,657 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 362 | 362 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AlphaQuest LLC | 1 | 0 | -1 | 0.00 | 0.00 | -0.00 | sell |
| ROTHSCHILD INVESTMENT LLC | 2 | 1 | -1 | 0.00 | 0.00 | -0.00 | sell |
| Measured Risk Portfolios, Inc. | 37 | 0 | -37 | 0.00 | 0.00 | -0.00 | sell |
| Corient Private Wealth LLC | 20,492 | 20,455 | -37 | 0.00 | 0.00 | -0.00 | sell |
| Sterling Capital Management LLC | 158 | 89 | -69 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 243 | 161 | -82 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 5,765 | 5,681 | -84 | 0.00 | 0.00 | -0.00 | sell |
| SIGNATUREFD, LLC | 128 | 42 | -86 | 0.00 | 0.00 | -0.00 | sell |
| HUNTINGTON NATIONAL BANK | 90 | 0 | -90 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 967 | 869 | -98 | 0.00 | 0.00 | +0.00 | sell |
| US BANCORP \DE\ | 123 | 16 | -107 | 0.00 | 0.00 | -0.00 | sell |
| QUADRANT CAPITAL GROUP LLC | 146 | 0 | -146 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 3,069 | 2,904 | -165 | 0.00 | 0.00 | -0.00 | sell |
| Creative Planning | 222 | 0 | -222 | 0.00 | 0.00 | -0.00 | sell |
| PNC FINANCIAL SERVICES GROUP, INC. | 1,798 | 1,571 | -227 | 0.00 | 0.00 | -0.00 | sell |
| Avior Wealth Management, LLC | 248 | 0 | -248 | 0.00 | 0.00 | -0.00 | sell |
| Caption Management, LLC | 199,898 | 199,508 | -390 | 0.13 | 0.13 | +0.00 | sell |
| EXCHANGE TRADED CONCEPTS, LLC | 9,608 | 9,138 | -470 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 568 | 74 | -494 | 0.00 | 0.00 | -0.00 | sell |
| KENNEDY CAPITAL MANAGEMENT LLC | 165,681 | 164,976 | -705 | 0.06 | 0.06 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 1,147 | 0 | -1,147 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 7,592 | 6,397 | -1,195 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 38,756 | 37,347 | -1,409 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 9,973 | 8,509 | -1,464 | 0.00 | 0.00 | -0.00 | sell |
| State of Wyoming | 5,402 | 2,889 | -2,513 | 0.01 | 0.01 | -0.01 | sell |
| MILLENNIUM MANAGEMENT LLC | 258,388 | 255,336 | -3,052 | 0.00 | 0.00 | +0.00 | sell |
| STATE STREET CORP | 176,377 | 172,904 | -3,473 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 18,841 | 13,283 | -5,558 | 0.00 | 0.00 | -0.00 | sell |
| BLUEFIN CAPITAL MANAGEMENT, LLC | 18,475 | 11,408 | -7,067 | 0.12 | 0.13 | +0.01 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 8,326 | 843 | -7,483 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 19,609 | 7,443 | -12,166 | 0.00 | 0.00 | -0.00 | sell |
| Pekin Hardy Strauss, Inc. | 17,750 | 0 | -17,750 | 0.03 | 0.00 | -0.03 | sell |
| VANGUARD GROUP INC | 607,721 | 588,323 | -19,398 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 72,452 | 52,873 | -19,579 | 0.00 | 0.00 | -0.00 | sell |
| ArrowMark Colorado Holdings LLC | 160,899 | 139,682 | -21,217 | 0.03 | 0.03 | -0.00 | sell |
| Russell Investments Group, Ltd. | 54,345 | 27,030 | -27,315 | 0.00 | 0.00 | -0.00 | sell |
| Rangeley Capital, LLC | 49,401 | 17,810 | -31,591 | 0.72 | 0.28 | -0.44 | sell |
| GSA CAPITAL PARTNERS LLP | 33,747 | 0 | -33,747 | 0.04 | 0.00 | -0.04 | sell |
| Alpha Wealth Funds, LLC | 77,933 | 38,647 | -39,286 | 1.23 | 0.59 | -0.65 | sell |
| GOLDMAN SACHS GROUP INC | 57,447 | 17,165 | -40,282 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 91,221 | 47,907 | -43,314 | 0.00 | 0.00 | -0.00 | sell |
| CSS LLC/IL | 51,712 | 0 | -51,712 | 0.05 | 0.00 | -0.05 | sell |
| MARSHALL WACE, LLP | 53,586 | 0 | -53,586 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 88,419 | 26,300 | -62,119 | 0.00 | 0.00 | -0.00 | sell |
| Slotnik Capital, LLC | 388,000 | 286,962 | -101,038 | 2.72 | 1.99 | -0.74 | sell |