| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) | Type |
|---|---|---|---|---|---|---|---|
| Soleus Capital Management, L.P. | 25,000 | 131,000 | +106,000 | 0.08 | 0.36 | +0.27 | buy |
| SummitTX Capital, L.P. | 82,885 | 137,821 | +54,936 | 0.20 | 0.30 | +0.10 | buy |
| PFM Health Sciences, LP | 265,517 | 305,431 | +39,914 | 2.12 | 2.16 | +0.04 | buy |
| Voleon Capital Management LP | 15,008 | 39,305 | +24,297 | 0.03 | 0.06 | +0.03 | buy |
| Harvest Investment Services, LLC | 5,049 | 6,413 | +1,364 | 0.08 | 0.08 | +0.00 | buy |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 22,883 | 22,584 | -299 | 0.03 | 0.03 | -0.01 | sell |
| PERCEPTIVE ADVISORS LLC | 1,452,707 | 1,442,707 | -10,000 | 2.10 | 1.92 | -0.19 | sell |
| Capital Research Global Investors | 421,575 | 392,847 | -28,728 | 0.01 | 0.00 | -0.00 | sell |
| Sofinnova Investments, Inc. | 454,657 | 406,029 | -48,628 | 1.55 | 1.37 | -0.18 | sell |