| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 555,473 | 1,115,424 | +559,951 | 0.00 | 0.00 | +0.00 | buy |
| Deep Track Capital, LP | 0 | 457,556 | +457,556 | 0.00 | 0.15 | +0.15 | buy |
| BlackRock, Inc. | 756,543 | 1,167,251 | +410,708 | 0.00 | 0.00 | -0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0 | 203,242 | +203,242 | 0.00 | 0.00 | +0.00 | buy |
| Ensign Peak Advisors, Inc | 0 | 194,200 | +194,200 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 210,676 | 315,663 | +104,987 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 72,826 | 128,083 | +55,257 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 18,497 | 62,696 | +44,199 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 21,328 | 64,747 | +43,419 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 33,757 | +33,757 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 167,538 | 191,122 | +23,584 | 0.00 | 0.00 | -0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 8,571 | 29,939 | +21,368 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 73,509 | 90,968 | +17,459 | 0.00 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 19,968 | 35,482 | +15,514 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 15,442 | +15,442 | 0.00 | 0.01 | +0.01 | buy |
| Swiss National Bank | 18,000 | 31,900 | +13,900 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 0 | 13,760 | +13,760 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 12,000 | +12,000 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 1,098,415 | 1,109,625 | +11,210 | 0.01 | 0.00 | -0.00 | buy |
| CATALYST PRIVATE WEALTH, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.05 | +0.05 | buy |
| Virtus Investment Advisers, LLC | 0 | 8,637 | +8,637 | 0.00 | 0.02 | +0.02 | buy |
| CITIGROUP INC | 9,577 | 15,085 | +5,508 | 0.00 | 0.00 | -0.00 | buy |
| MetLife Investment Management, LLC | 5,710 | 10,863 | +5,153 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 5,305 | 9,887 | +4,582 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 2,317 | 6,502 | +4,185 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 4,824 | 8,967 | +4,143 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 10,249 | 14,358 | +4,109 | 0.00 | 0.00 | -0.00 | buy |
| Corebridge Financial, Inc. | 4,618 | 8,271 | +3,653 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 7,170 | 10,554 | +3,384 | 0.00 | 0.00 | -0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 2,003 | 4,532 | +2,529 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 77,275 | 78,931 | +1,656 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 0 | 998 | +998 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 10 | 918 | +908 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 9,523 | 10,296 | +773 | 0.00 | 0.00 | -0.00 | buy |
| Woodline Partners LP | 181,530 | 182,028 | +498 | 0.02 | 0.01 | -0.01 | buy |
| AMALGAMATED BANK | 317 | 582 | +265 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 741 | 922 | +181 | 0.00 | 0.00 | +0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 768 | 936 | +168 | 0.00 | 0.00 | -0.00 | buy |
| US BANCORP \DE\ | 0 | 144 | +144 | 0.00 | 0.00 | +0.00 | buy |
| SIGNATUREFD, LLC | 0 | 137 | +137 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 1 | 59 | +58 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 1,219 | 1,266 | +47 | 0.00 | 0.00 | -0.00 | buy |
| Allworth Financial LP | 0 | 15 | +15 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 0 | 3 | +3 | 0.00 | 0.00 | +0.00 | buy |
| Sterling Capital Management LLC | 143 | 145 | +2 | 0.00 | 0.00 | -0.00 | buy |
| Ameritas Investment Partners, Inc. | 941 | 941 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ARCH Venture Management, LLC | 3,728,738 | 3,728,738 | 0 | 28.73 | 18.21 | -10.52 | hold |
| Daiwa Securities Group Inc. | 121 | 121 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Capital International Investors | 2,602,529 | 2,602,529 | 0 | 0.01 | 0.01 | -0.00 | hold |
| ACUTA CAPITAL PARTNERS, LLC | 16,400 | 16,400 | 0 | 0.29 | 0.19 | -0.10 | hold |
| Cormorant Asset Management, LP | 2,940,921 | 2,940,921 | 0 | 2.87 | 2.23 | -0.63 | hold |
| Sofinnova Investments, Inc. | 1,995,594 | 1,995,594 | 0 | 2.59 | 1.51 | -1.09 | hold |
| KLP KAPITALFORVALTNING AS | 1,900 | 1,900 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Logos Global Management LP | 208,910 | 208,910 | 0 | 0.43 | 0.37 | -0.06 | hold |
| TRV GP VI, LLC | 969,218 | 969,218 | 0 | 14.71 | 23.16 | +8.45 | hold |
| TRV GP V, LLC | 7,135,233 | 7,135,233 | 0 | 43.06 | 57.21 | +14.15 | hold |
| JOHNSON & JOHNSON | 2,498,051 | 2,498,051 | 0 | 11.48 | 7.33 | -4.15 | hold |
| Tidemark, LLC | 1,088 | 1,088 | 0 | 0.01 | 0.00 | -0.00 | hold |
| FMR LLC | 5,486,468 | 5,486,468 | 0 | 0.01 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 3,500 | 3,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STRS OHIO | 1,700 | 1,700 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Aster Capital Management (DIFC) Ltd | 5 | 0 | -5 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 18 | 0 | -18 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 1,412 | 1,209 | -203 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 7,756 | 7,337 | -419 | 0.01 | 0.01 | -0.01 | sell |
| ALPS ADVISORS INC | 29,580 | 26,128 | -3,452 | 0.00 | 0.00 | -0.00 | sell |
| VIRTUS ADVISERS, LLC | 3,740 | 0 | -3,740 | 0.03 | 0.00 | -0.03 | sell |
| Sandia Investment Management LP | 5,000 | 0 | -5,000 | 0.17 | 0.00 | -0.17 | sell |
| Siren, L.L.C. | 384,197 | 378,469 | -5,728 | 0.30 | 0.21 | -0.09 | sell |
| GOLDMAN SACHS GROUP INC | 1,252,136 | 1,244,310 | -7,826 | 0.00 | 0.00 | -0.00 | sell |
| TD ASSET MANAGEMENT INC | 177,906 | 162,818 | -15,088 | 0.00 | 0.00 | -0.00 | sell |
| LMR Partners LLP | 20,000 | 0 | -20,000 | 0.01 | 0.00 | -0.01 | sell |
| Crestline Management, LP | 27,496 | 0 | -27,496 | 0.02 | 0.00 | -0.02 | sell |
| NORGES BANK | 48,452 | 0 | -48,452 | 0.00 | 0.00 | -0.00 | sell |
| JENNISON ASSOCIATES LLC | 62,287 | 0 | -62,287 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,143,384 | 1,073,208 | -70,176 | 0.00 | 0.00 | -0.00 | sell |
| T. Rowe Price Investment Management, Inc. | 1,636,931 | 1,551,925 | -85,006 | 0.02 | 0.01 | -0.01 | sell |
| CITADEL ADVISORS LLC | 487,458 | 249,414 | -238,044 | 0.01 | 0.00 | -0.01 | sell |
| PERCEPTIVE ADVISORS LLC | 311,551 | 0 | -311,551 | 0.15 | 0.00 | -0.15 | sell |