| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| NORGES BANK | 0 | 3,768,619 | +3,768,619 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 463,001 | 1,012,044 | +549,043 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 0 | 498,490 | +498,490 | 0.00 | 0.02 | +0.02 | buy |
| AQR CAPITAL MANAGEMENT LLC | 72,171 | 544,869 | +472,698 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 126,000 | 511,546 | +385,546 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 3,370,689 | 3,753,358 | +382,669 | 0.00 | 0.00 | -0.00 | buy |
| Qube Research & Technologies Ltd | 619,321 | 978,500 | +359,179 | 0.01 | 0.01 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 48,460 | 391,762 | +343,302 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 80,002 | 381,613 | +301,611 | 0.00 | 0.00 | +0.00 | buy |
| Trexquant Investment LP | 176,657 | 466,430 | +289,773 | 0.01 | 0.02 | +0.01 | buy |
| Voleon Capital Management LP | 0 | 285,234 | +285,234 | 0.00 | 0.04 | +0.04 | buy |
| Point72 Asset Management, L.P. | 178,168 | 453,011 | +274,843 | 0.00 | 0.00 | +0.00 | buy |
| Sixth Street Partners Management Company, L.P. | 0 | 262,456 | +262,456 | 0.00 | 0.00 | +0.00 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | 253,092 | +253,092 | 0.00 | 0.01 | +0.01 | buy |
| Squarepoint Ops LLC | 44,626 | 290,904 | +246,278 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 820,480 | 1,036,044 | +215,564 | 0.01 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 937,323 | 1,143,775 | +206,452 | 0.01 | 0.01 | -0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 175,110 | +175,110 | 0.00 | 0.00 | +0.00 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 185,087 | 357,756 | +172,669 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 170,590 | +170,590 | 0.00 | 0.00 | +0.00 | buy |
| Parkman Healthcare Partners LLC | 786,783 | 935,247 | +148,464 | 0.73 | 0.66 | -0.07 | buy |
| ALGERT GLOBAL LLC | 0 | 118,630 | +118,630 | 0.00 | 0.01 | +0.01 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 62,100 | 131,300 | +69,200 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 161,349 | 225,760 | +64,411 | 0.01 | 0.01 | -0.00 | buy |
| FMR LLC | 8,101,563 | 8,162,897 | +61,334 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 705,350 | 766,323 | +60,973 | 0.00 | 0.00 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 180,889 | 241,447 | +60,558 | 0.00 | 0.00 | -0.00 | buy |
| EntryPoint Capital, LLC | 73,568 | 129,446 | +55,878 | 0.19 | 0.22 | +0.02 | buy |
| Man Group plc | 21,154 | 73,823 | +52,669 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 0 | 50,369 | +50,369 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 3,647 | 47,458 | +43,811 | 0.00 | 0.00 | +0.00 | buy |
| Virtus Investment Advisers, LLC | 10,046 | 53,638 | +43,592 | 0.02 | 0.09 | +0.06 | buy |
| Allspring Global Investments Holdings, LLC | 0 | 43,182 | +43,182 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 42,325 | +42,325 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 260,992 | 297,346 | +36,354 | 0.00 | 0.00 | -0.00 | buy |
| CITIGROUP INC | 5,055 | 40,339 | +35,284 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 209,277 | 242,346 | +33,069 | 0.03 | 0.02 | -0.01 | buy |
| GSA CAPITAL PARTNERS LLP | 39,232 | 69,348 | +30,116 | 0.02 | 0.03 | +0.01 | buy |
| Quantbot Technologies LP | 663 | 28,178 | +27,515 | 0.00 | 0.01 | +0.01 | buy |
| nVerses Capital, LLC | 0 | 24,029 | +24,029 | 0.00 | 0.26 | +0.26 | buy |
| Graham Capital Management, L.P. | 0 | 22,508 | +22,508 | 0.00 | 0.00 | +0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 0 | 22,385 | +22,385 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 31,010 | 51,680 | +20,670 | 0.00 | 0.00 | -0.00 | buy |
| SG Americas Securities, LLC | 0 | 20,338 | +20,338 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 0 | 20,026 | +20,026 | 0.00 | 0.00 | +0.00 | buy |
| WINTON GROUP Ltd | 0 | 19,800 | +19,800 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 0 | 19,535 | +19,535 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 0 | 17,988 | +17,988 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 10,850 | 28,483 | +17,633 | 0.00 | 0.00 | +0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 0 | 13,352 | +13,352 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 40,510 | 53,397 | +12,887 | 0.00 | 0.00 | -0.00 | buy |
| Engineers Gate Manager LP | 0 | 12,491 | +12,491 | 0.00 | 0.00 | +0.00 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 0 | 11,500 | +11,500 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 43,992 | 55,228 | +11,236 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 18,402 | 29,497 | +11,095 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 10,550 | +10,550 | 0.00 | 0.01 | +0.01 | buy |
| AMERIPRISE FINANCIAL INC | 0 | 10,487 | +10,487 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 0 | 10,017 | +10,017 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 75,536 | 84,770 | +9,234 | 0.00 | 0.00 | -0.00 | buy |
| Propel Bio Management, LLC | 341,779 | 350,389 | +8,610 | 1.95 | 1.27 | -0.69 | buy |
| Shay Capital LLC | 10,000 | 18,000 | +8,000 | 0.01 | 0.01 | +0.00 | buy |
| Mariner, LLC | 27,314 | 33,141 | +5,827 | 0.00 | 0.00 | -0.00 | buy |
| Quantinno Capital Management LP | 49,389 | 54,838 | +5,449 | 0.00 | 0.00 | -0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 100 | 5,200 | +5,100 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 257,729 | 262,456 | +4,727 | 0.00 | 0.00 | -0.00 | buy |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 0 | 4,700 | +4,700 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 24,720 | 29,208 | +4,488 | 0.00 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 81,383 | 85,747 | +4,364 | 0.00 | 0.00 | -0.00 | buy |
| UBS Group AG | 231,254 | 234,714 | +3,460 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 1,425 | 4,788 | +3,363 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 9,609 | 12,561 | +2,952 | 0.00 | 0.00 | -0.00 | buy |
| Integrated Wealth Concepts LLC | 0 | 2,479 | +2,479 | 0.00 | 0.00 | +0.00 | buy |
| STRS OHIO | 9,800 | 12,000 | +2,200 | 0.00 | 0.00 | -0.00 | buy |
| Arax Advisory Partners | 77 | 1,771 | +1,694 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 26,434 | 28,058 | +1,624 | 0.00 | 0.00 | -0.00 | buy |
| Global Retirement Partners, LLC | 273 | 1,870 | +1,597 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 19,380 | 20,852 | +1,472 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 41,203 | 42,384 | +1,181 | 0.00 | 0.00 | -0.00 | buy |
| Quarry LP | 0 | 893 | +893 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 15,608 | 16,217 | +609 | 0.00 | 0.00 | -0.00 | buy |
| Allworth Financial LP | 263 | 778 | +515 | 0.00 | 0.00 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 477 | 965 | +488 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 715 | 1,164 | +449 | 0.00 | 0.00 | -0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 15,338 | 15,735 | +397 | 0.00 | 0.00 | -0.00 | buy |
| Farther Finance Advisors, LLC | 0 | 353 | +353 | 0.00 | 0.00 | +0.00 | buy |
| IFP Advisors, Inc | 1 | 242 | +241 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 61 | 287 | +226 | 0.00 | 0.00 | +0.00 | buy |
| Physician Wealth Advisors, Inc. | 0 | 160 | +160 | 0.00 | 0.00 | +0.00 | buy |
| DnB Asset Management AS | 23,515 | 23,600 | +85 | 0.00 | 0.00 | -0.00 | buy |
| SJS Investment Consulting Inc. | 2 | 76 | +74 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 222 | 272 | +50 | 0.00 | 0.00 | +0.00 | buy |
| Covestor Ltd | 4 | 39 | +35 | 0.00 | 0.00 | 0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 20 | +20 | 0.00 | 0.00 | +0.00 | buy |
| Clearstead Advisors, LLC | 0 | 15 | +15 | 0.00 | 0.00 | +0.00 | buy |
| JPL Wealth Management, LLC | 0 | 14 | +14 | 0.00 | 0.00 | +0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| ORBIMED ADVISORS LLC | 5,693,589 | 5,693,589 | 0 | 1.12 | 0.75 | -0.37 | hold |
| Ameritas Investment Partners, Inc. | 2,741 | 2,741 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Altshuler Shaham Ltd | 380,061 | 380,061 | 0 | 0.06 | 0.03 | -0.03 | hold |
| Swiss National Bank | 48,100 | 48,100 | 0 | 0.00 | 0.00 | -0.00 | hold |