| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 517,479 | 2,999,154 | +2,481,675 | 0.00 | 0.00 | +0.00 | buy |
| BOONE CAPITAL MANAGEMENT LLC | 0 | 1,254,658 | +1,254,658 | 0.00 | 3.06 | +3.06 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 0 | 917,898 | +917,898 | 0.00 | 1.07 | +1.07 | buy |
| Nantahala Capital Management, LLC | 3,509,850 | 4,369,665 | +859,815 | 1.38 | 1.76 | +0.37 | buy |
| MORGAN STANLEY | 315,672 | 969,276 | +653,604 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 482,619 | 1,105,862 | +623,243 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 233,759 | 831,132 | +597,373 | 0.00 | 0.00 | +0.00 | buy |
| NAN FUNG TRINITY (HK) Ltd | 0 | 560,770 | +560,770 | 0.00 | 0.38 | +0.38 | buy |
| VANGUARD GROUP INC | 2,020,185 | 2,507,023 | +486,838 | 0.00 | 0.00 | +0.00 | buy |
| AWM Investment Company, Inc. | 0 | 470,000 | +470,000 | 0.00 | 0.30 | +0.30 | buy |
| STATE STREET CORP | 195,604 | 585,880 | +390,276 | 0.00 | 0.00 | +0.00 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2,691,628 | 3,072,985 | +381,357 | 0.02 | 0.03 | +0.01 | buy |
| Propel Bio Management, LLC | 624,022 | 974,022 | +350,000 | 3.45 | 6.71 | +3.26 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 0 | 268,148 | +268,148 | 0.00 | 0.01 | +0.01 | buy |
| NORTHERN TRUST CORP | 180,820 | 434,222 | +253,402 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 129,415 | 329,884 | +200,469 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 131,537 | 299,937 | +168,400 | 0.00 | 0.00 | +0.00 | buy |
| Simplify Asset Management Inc. | 408,584 | 558,584 | +150,000 | 0.09 | 0.19 | +0.10 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 131,945 | +131,945 | 0.00 | 0.00 | +0.00 | buy |
| Diametric Capital, LP | 18,754 | 138,363 | +119,609 | 0.11 | 0.42 | +0.31 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 24,457 | 134,352 | +109,895 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 37,941 | 141,978 | +104,037 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 102,336 | +102,336 | 0.00 | 0.01 | +0.01 | buy |
| Bank of New York Mellon Corp | 121,452 | 212,179 | +90,727 | 0.00 | 0.00 | +0.00 | buy |
| 683 Capital Management, LLC | 675,000 | 750,000 | +75,000 | 0.33 | 0.43 | +0.11 | buy |
| RHUMBLINE ADVISERS | 1,854 | 67,505 | +65,651 | 0.00 | 0.00 | +0.00 | buy |
| Jain Global LLC | 45,940 | 111,277 | +65,337 | 0.00 | 0.01 | +0.01 | buy |
| Knoll Capital Management, LLC | 0 | 62,689 | +62,689 | 0.00 | 0.25 | +0.25 | buy |
| Nuveen, LLC | 0 | 56,719 | +56,719 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 54,134 | +54,134 | 0.00 | 0.03 | +0.03 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 621,763 | 672,003 | +50,240 | 0.07 | 0.09 | +0.02 | buy |
| Stonepine Capital Management, LLC | 0 | 45,000 | +45,000 | 0.00 | 0.25 | +0.25 | buy |
| DEUTSCHE BANK AG\ | 0 | 37,065 | +37,065 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 11,389 | 38,859 | +27,470 | 0.00 | 0.01 | +0.00 | buy |
| MetLife Investment Management, LLC | 0 | 26,626 | +26,626 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0 | 23,906 | +23,906 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 0 | 22,915 | +22,915 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 0 | 22,860 | +22,860 | 0.00 | 0.00 | +0.00 | buy |
| Corient Private Wealth LLC | 0 | 22,416 | +22,416 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 0 | 21,909 | +21,909 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 0 | 21,765 | +21,765 | 0.00 | 0.00 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 153,121 | 174,514 | +21,393 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 21,049 | +21,049 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 527,558 | 548,057 | +20,499 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 0 | 17,920 | +17,920 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 99,319 | 116,942 | +17,623 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | 17,000 | +17,000 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0 | 16,913 | +16,913 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 0 | 12,274 | +12,274 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 0 | 11,794 | +11,794 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 0 | 11,005 | +11,005 | 0.00 | 0.00 | +0.00 | buy |
| Riverwater Partners LLC | 0 | 10,894 | +10,894 | 0.00 | 0.03 | +0.03 | buy |
| Trexquant Investment LP | 119,274 | 127,195 | +7,921 | 0.01 | 0.01 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 7,451 | +7,451 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 0 | 7,080 | +7,080 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 5,058 | +5,058 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 0 | 4,815 | +4,815 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 0 | 4,459 | +4,459 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 10,005 | 14,310 | +4,305 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 0 | 3,550 | +3,550 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 0 | 2,725 | +2,725 | 0.00 | 0.00 | +0.00 | buy |
| Truvestments Capital LLC | 51 | 2,759 | +2,708 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 0 | 2,393 | +2,393 | 0.00 | 0.01 | +0.01 | buy |
| AMALGAMATED BANK | 0 | 1,492 | +1,492 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 58,310 | 58,998 | +688 | 0.00 | 0.00 | +0.00 | buy |
| Farther Finance Advisors, LLC | 0 | 380 | +380 | 0.00 | 0.00 | +0.00 | buy |
| Vermillion & White Wealth Management Group, LLC | 0 | 370 | +370 | 0.00 | 0.00 | +0.00 | buy |
| SIGNATUREFD, LLC | 0 | 175 | +175 | 0.00 | 0.00 | +0.00 | buy |
| Sterling Capital Management LLC | 0 | 162 | +162 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 1,620 | 1,620 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Palo Alto Investors LP | 108,865 | 108,865 | 0 | 0.10 | 0.13 | +0.03 | hold |
| Newtyn Management, LLC | 480,000 | 480,000 | 0 | 0.36 | 0.41 | +0.05 | hold |
| NewEdge Advisors, LLC | 1 | 1 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Darwin Wealth Management, LLC | 26 | 26 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Vivo Capital, LLC | 1,842,751 | 1,842,751 | 0 | 1.16 | 1.07 | -0.09 | hold |
| Parallel Advisors, LLC | 400 | 400 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Game Plan Financial Advisors, LLC | 2,350 | 2,350 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Activest Wealth Management | 120 | 120 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| JONES FINANCIAL COMPANIES LLLP | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Avion Wealth | 85 | 0 | -85 | 0.00 | 0.00 | 0.00 | sell |
| SBI Securities Co., Ltd. | 558 | 162 | -396 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 84,765 | 76,401 | -8,364 | 0.00 | 0.00 | -0.00 | sell |
| Cannon Global Investment Management, LLC | 14,000 | 0 | -14,000 | 0.18 | 0.00 | -0.18 | sell |
| Jefferies Financial Group Inc. | 18,000 | 0 | -18,000 | 0.00 | 0.00 | -0.00 | sell |
| Engineers Gate Manager LP | 20,501 | 0 | -20,501 | 0.00 | 0.00 | -0.00 | sell |
| ExodusPoint Capital Management, LP | 24,409 | 0 | -24,409 | 0.00 | 0.00 | -0.00 | sell |
| Quantessence Capital LLC | 26,087 | 0 | -26,087 | 0.03 | 0.00 | -0.03 | sell |
| LMR Partners LLP | 27,120 | 0 | -27,120 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 32,044 | 0 | -32,044 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 128,919 | 68,614 | -60,305 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 200,450 | 137,146 | -63,304 | 0.00 | 0.00 | -0.00 | sell |
| GSA CAPITAL PARTNERS LLP | 63,835 | 0 | -63,835 | 0.03 | 0.00 | -0.03 | sell |
| Schonfeld Strategic Advisors LLC | 65,011 | 0 | -65,011 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 100,141 | 33,793 | -66,348 | 0.00 | 0.00 | -0.00 | sell |
| OMERS ADMINISTRATION Corp | 72,200 | 0 | -72,200 | 0.00 | 0.00 | -0.00 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 73,849 | 0 | -73,849 | 0.00 | 0.00 | -0.00 | sell |
| Connective Capital Management, LLC | 74,913 | 0 | -74,913 | 0.33 | 0.00 | -0.33 | sell |
| HRT FINANCIAL LP | 96,655 | 0 | -96,655 | 0.00 | 0.00 | -0.00 | sell |
| Walleye Capital LLC | 183,306 | 0 | -183,306 | 0.01 | 0.00 | -0.01 | sell |