| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BROADWOOD CAPITAL INC | 12,455,264 | 13,519,491 | +1,064,227 | 17.79 | 14.78 | -3.01 | buy |
| MORGAN STANLEY | 758,789 | 1,312,303 | +553,514 | 0.00 | 0.00 | +0.00 | buy |
| Yunqi Capital Ltd | 1,937,589 | 2,411,288 | +473,699 | 33.61 | 28.88 | -4.73 | buy |
| Soleus Capital Management, L.P. | 2,562,893 | 2,984,733 | +421,840 | 3.54 | 3.46 | -0.08 | buy |
| FEDERATED HERMES, INC. | 0 | 363,233 | +363,233 | 0.00 | 0.01 | +0.01 | buy |
| TWO SIGMA INVESTMENTS, LP | 88,404 | 407,381 | +318,977 | 0.00 | 0.01 | +0.01 | buy |
| CITADEL ADVISORS LLC | 247,491 | 555,116 | +307,625 | 0.00 | 0.01 | +0.00 | buy |
| Palo Alto Investors LP | 525,017 | 791,879 | +266,862 | 1.76 | 2.83 | +1.06 | buy |
| Resona Asset Management Co.,Ltd. | 2,169,618 | 2,421,836 | +252,218 | 0.22 | 0.20 | -0.02 | buy |
| Susquehanna Portfolio Strategies, LLC | 0 | 188,688 | +188,688 | 0.00 | 0.07 | +0.07 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 57,634 | 243,470 | +185,836 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 985,610 | 1,153,895 | +168,285 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 108,845 | 240,585 | +131,740 | 0.03 | 0.05 | +0.02 | buy |
| Assenagon Asset Management S.A. | 52,402 | 164,088 | +111,686 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 107,064 | +107,064 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 54,153 | 153,371 | +99,218 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 99,141 | +99,141 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 123,347 | 219,179 | +95,832 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 40,778 | 124,287 | +83,509 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 419,350 | 474,281 | +54,931 | 0.00 | 0.00 | -0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 26,545 | 73,376 | +46,831 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 68,882 | 105,943 | +37,061 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 8,951 | 40,263 | +31,312 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 236,838 | 267,674 | +30,836 | 0.00 | 0.00 | +0.00 | buy |
| NOMURA HOLDINGS INC | 0 | 29,919 | +29,919 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 26,362 | +26,362 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 63,254 | 87,646 | +24,392 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 182,998 | 205,965 | +22,967 | 0.00 | 0.00 | -0.00 | buy |
| HRT FINANCIAL LP | 0 | 22,720 | +22,720 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 0 | 21,885 | +21,885 | 0.00 | 0.00 | +0.00 | buy |
| AXQ CAPITAL, LP | 0 | 20,650 | +20,650 | 0.00 | 0.11 | +0.11 | buy |
| Quantbot Technologies LP | 92,883 | 112,518 | +19,635 | 0.05 | 0.05 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 0 | 19,457 | +19,457 | 0.00 | 0.00 | +0.00 | buy |
| Atika Capital Management LLC | 0 | 16,400 | +16,400 | 0.00 | 0.03 | +0.03 | buy |
| BARCLAYS PLC | 83,136 | 95,929 | +12,793 | 0.00 | 0.00 | -0.00 | buy |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 156,225 | 168,755 | +12,530 | 0.01 | 0.01 | +0.00 | buy |
| FMR LLC | 3,789 | 15,268 | +11,479 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 31,835 | 42,067 | +10,232 | 0.03 | 0.03 | +0.00 | buy |
| STATE STREET CORP | 1,994,906 | 2,002,876 | +7,970 | 0.00 | 0.00 | -0.00 | buy |
| AlphaQuest LLC | 3,658 | 10,879 | +7,221 | 0.01 | 0.02 | +0.01 | buy |
| Bank of New York Mellon Corp | 300,524 | 306,688 | +6,164 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 138,505 | 144,394 | +5,889 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 29,071 | 34,218 | +5,147 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 1,246 | 5,919 | +4,673 | 0.00 | 0.00 | +0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 0 | 3,607 | +3,607 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,189,486 | 1,192,821 | +3,335 | 0.00 | 0.00 | -0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 12,293 | 15,276 | +2,983 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 41,727 | 44,531 | +2,804 | 0.00 | 0.00 | -0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 49,290 | 52,059 | +2,769 | 0.00 | 0.00 | -0.00 | buy |
| Creative Planning | 13,089 | 15,695 | +2,606 | 0.00 | 0.00 | +0.00 | buy |
| State of Alaska, Department of Revenue | 27,295 | 29,476 | +2,181 | 0.01 | 0.01 | -0.00 | buy |
| FRANKLIN RESOURCES INC | 34,163 | 35,175 | +1,012 | 0.00 | 0.00 | -0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 21,234 | 22,168 | +934 | 0.00 | 0.00 | -0.00 | buy |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS | 11,788 | 12,711 | +923 | 0.00 | 0.00 | -0.00 | buy |
| STRS OHIO | 10,800 | 11,600 | +800 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 898 | 1,563 | +665 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 13,395 | 13,829 | +434 | 0.00 | 0.00 | -0.00 | buy |
| BNP Paribas Asset Management Holding S.A. | 0 | 424 | +424 | 0.00 | 0.00 | +0.00 | buy |
| Smartleaf Asset Management LLC | 897 | 1,320 | +423 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 831 | 1,150 | +319 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Trading LLC | 620 | 930 | +310 | 0.00 | 0.00 | +0.00 | buy |
| Sterling Capital Management LLC | 51 | 294 | +243 | 0.00 | 0.00 | +0.00 | buy |
| THRIVENT FINANCIAL FOR LUTHERANS | 36,182 | 36,405 | +223 | 0.00 | 0.00 | -0.00 | buy |
| UMB Bank, n.a. | 54 | 260 | +206 | 0.00 | 0.00 | +0.00 | buy |
| FIFTH THIRD BANCORP | 396 | 585 | +189 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 24,767 | 24,941 | +174 | 0.00 | 0.00 | -0.00 | buy |
| Parallel Advisors, LLC | 34 | 201 | +167 | 0.00 | 0.00 | +0.00 | buy |
| Aquatic Capital Management LLC | 0 | 157 | +157 | 0.00 | 0.00 | +0.00 | buy |
| Fortitude Family Office, LLC | 0 | 155 | +155 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 183 | 327 | +144 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 95 | 213 | +118 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 53,762 | 53,862 | +100 | 0.00 | 0.00 | -0.00 | buy |
| Farther Finance Advisors, LLC | 291 | 377 | +86 | 0.00 | 0.00 | -0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 676 | 749 | +73 | 0.00 | 0.00 | -0.00 | buy |
| SBI Securities Co., Ltd. | 97 | 167 | +70 | 0.00 | 0.00 | +0.00 | buy |
| Parkside Financial Bank & Trust | 20 | 73 | +53 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 0 | 45 | +45 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 4 | 39 | +35 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 0 | 29 | +29 | 0.00 | 0.00 | +0.00 | buy |
| Annis Gardner Whiting Capital Advisors, LLC | 0 | 17 | +17 | 0.00 | 0.00 | +0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 0 | 17 | +17 | 0.00 | 0.00 | +0.00 | buy |
| Clearstead Trust, LLC | 0 | 16 | +16 | 0.00 | 0.00 | +0.00 | buy |
| US BANCORP \DE\ | 2,044 | 2,051 | +7 | 0.00 | 0.00 | -0.00 | buy |
| Ameritas Advisory Services, LLC | 0 | 5 | +5 | 0.00 | 0.00 | +0.00 | buy |
| TWIN PEAKS WEALTH ADVISORS, LLC | 0 | 2 | +2 | 0.00 | 0.00 | +0.00 | buy |
| HARBOR CAPITAL ADVISORS, INC. | 90 | 91 | +1 | 0.00 | 0.00 | -0.00 | buy |
| Ameritas Investment Partners, Inc. | 4,831 | 4,831 | 0 | 0.00 | 0.00 | -0.00 | hold |
| OREGON PUBLIC EMPLOYEES RETIREMENT FUND | 11,300 | 11,300 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 60,470 | 60,470 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FARMERS & MERCHANTS INVESTMENTS INC | 25 | 25 | 0 | 0.00 | 0.00 | -0.00 | hold |
| JANUS HENDERSON GROUP PLC | 18,934 | 18,934 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 14,076 | 14,076 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Colonial Trust Advisors | 300 | 300 | 0 | 0.00 | 0.00 | -0.00 | hold |
| IFP Advisors, Inc | 0 | 0 | 0 | 0.00 | 0.00 | +0.00 | hold |
| KLP KAPITALFORVALTNING AS | 7,400 | 7,400 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FNY Investment Advisers, LLC | 170 | 170 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Golden State Wealth Management, LLC | 40 | 40 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Williams Jones Wealth Management, LLC. | 18,900 | 18,900 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Avion Wealth | 100 | 100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Maryland State Retirement & Pension System | 14,363 | 14,363 | 0 | 0.01 | 0.01 | -0.00 | hold |