| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BROADWOOD CAPITAL INC | 12,455,264 | 13,519,491 | +1,064,227 | 17.79 | 14.78 | -3.01 | buy |
| BlackRock, Inc. | 7,747,716 | 7,371,147 | -376,569 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 5,415,710 | 4,390,767 | -1,024,943 | 0.00 | 0.00 | -0.00 | sell |
| Soleus Capital Management, L.P. | 2,562,893 | 2,984,733 | +421,840 | 3.54 | 3.46 | -0.08 | buy |
| ARMISTICE CAPITAL, LLC | 3,000,000 | 2,812,000 | -188,000 | 1.41 | 1.79 | +0.38 | sell |
| Resona Asset Management Co.,Ltd. | 2,169,618 | 2,421,836 | +252,218 | 0.22 | 0.20 | -0.02 | buy |
| Yunqi Capital Ltd | 1,937,589 | 2,411,288 | +473,699 | 33.61 | 28.88 | -4.73 | buy |
| STATE STREET CORP | 1,994,906 | 2,002,876 | +7,970 | 0.00 | 0.00 | -0.00 | buy |
| MORGAN STANLEY | 758,789 | 1,312,303 | +553,514 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,189,486 | 1,192,821 | +3,335 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 985,610 | 1,153,895 | +168,285 | 0.00 | 0.00 | +0.00 | buy |
| Palo Alto Investors LP | 525,017 | 791,879 | +266,862 | 1.76 | 2.83 | +1.06 | buy |
| DIMENSIONAL FUND ADVISORS LP | 879,686 | 785,586 | -94,100 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN CAPITAL MANAGEMENT INC | 1,010,164 | 784,914 | -225,250 | 0.72 | 0.55 | -0.18 | sell |
| Defender Capital, LLC. | 720,532 | 695,764 | -24,768 | 4.99 | 3.96 | -1.03 | sell |
| CITADEL ADVISORS LLC | 247,491 | 555,116 | +307,625 | 0.00 | 0.01 | +0.00 | buy |
| JUPITER ASSET MANAGEMENT LTD | 566,079 | 539,070 | -27,009 | 0.10 | 0.08 | -0.02 | sell |
| NORTHERN TRUST CORP | 528,314 | 512,711 | -15,603 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 419,350 | 474,281 | +54,931 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 88,404 | 407,381 | +318,977 | 0.00 | 0.01 | +0.01 | buy |
| FEDERATED HERMES, INC. | 0 | 363,233 | +363,233 | 0.00 | 0.01 | +0.01 | buy |
| Bank of New York Mellon Corp | 300,524 | 306,688 | +6,164 | 0.00 | 0.00 | -0.00 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 501,197 | 293,080 | -208,117 | 0.03 | 0.02 | -0.01 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 300,204 | 291,568 | -8,636 | 0.00 | 0.00 | -0.00 | sell |
| UBS Group AG | 236,838 | 267,674 | +30,836 | 0.00 | 0.00 | +0.00 | buy |
| Ensign Peak Advisors, Inc | 289,715 | 248,394 | -41,321 | 0.01 | 0.01 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 57,634 | 243,470 | +185,836 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 108,845 | 240,585 | +131,740 | 0.03 | 0.05 | +0.02 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 123,347 | 219,179 | +95,832 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 182,998 | 205,965 | +22,967 | 0.00 | 0.00 | -0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 0 | 188,688 | +188,688 | 0.00 | 0.07 | +0.07 | buy |
| GOLDMAN SACHS GROUP INC | 544,843 | 182,239 | -362,604 | 0.00 | 0.00 | -0.00 | sell |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 156,225 | 168,755 | +12,530 | 0.01 | 0.01 | +0.00 | buy |
| Assenagon Asset Management S.A. | 52,402 | 164,088 | +111,686 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 54,153 | 153,371 | +99,218 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 227,320 | 149,940 | -77,380 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 138,505 | 144,394 | +5,889 | 0.00 | 0.00 | -0.00 | buy |
| WINTON GROUP Ltd | 190,528 | 138,408 | -52,120 | 0.20 | 0.12 | -0.09 | sell |
| Nuveen, LLC | 156,747 | 131,041 | -25,706 | 0.00 | 0.00 | -0.00 | sell |
| D. E. Shaw & Co., Inc. | 40,778 | 124,287 | +83,509 | 0.00 | 0.00 | +0.00 | buy |
| Quantbot Technologies LP | 92,883 | 112,518 | +19,635 | 0.05 | 0.05 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 175,977 | 109,608 | -66,369 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 0 | 107,064 | +107,064 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 68,882 | 105,943 | +37,061 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 122,850 | 100,989 | -21,861 | 0.01 | 0.01 | -0.00 | sell |
| AMERIPRISE FINANCIAL INC | 111,463 | 99,372 | -12,091 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 0 | 99,141 | +99,141 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 83,136 | 95,929 | +12,793 | 0.00 | 0.00 | -0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 63,254 | 87,646 | +24,392 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 26,545 | 73,376 | +46,831 | 0.00 | 0.00 | +0.00 | buy |
| Swiss National Bank | 77,100 | 65,900 | -11,200 | 0.00 | 0.00 | -0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 60,470 | 60,470 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CANADA LIFE ASSURANCE Co | 56,180 | 55,646 | -534 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 53,762 | 53,862 | +100 | 0.00 | 0.00 | -0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 49,290 | 52,059 | +2,769 | 0.00 | 0.00 | -0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 41,727 | 44,531 | +2,804 | 0.00 | 0.00 | -0.00 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 45,568 | 43,464 | -2,104 | 0.01 | 0.01 | -0.01 | sell |
| XTX Topco Ltd | 31,835 | 42,067 | +10,232 | 0.03 | 0.03 | +0.00 | buy |
| ROYAL BANK OF CANADA | 8,951 | 40,263 | +31,312 | 0.00 | 0.00 | +0.00 | buy |
| Raiffeisen Bank International AG | 80,000 | 40,000 | -40,000 | 0.02 | 0.01 | -0.01 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 37,530 | 37,028 | -502 | 0.00 | 0.00 | -0.00 | sell |
| THRIVENT FINANCIAL FOR LUTHERANS | 36,182 | 36,405 | +223 | 0.00 | 0.00 | -0.00 | buy |
| FRANKLIN RESOURCES INC | 34,163 | 35,175 | +1,012 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 29,071 | 34,218 | +5,147 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 41,079 | 32,599 | -8,480 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 65,400 | 31,900 | -33,500 | 0.00 | 0.00 | -0.00 | sell |
| NOMURA HOLDINGS INC | 0 | 29,919 | +29,919 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 30,108 | 29,827 | -281 | 0.00 | 0.00 | +0.00 | sell |
| State of Alaska, Department of Revenue | 27,295 | 29,476 | +2,181 | 0.01 | 0.01 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 29,390 | 27,354 | -2,036 | 0.00 | 0.00 | -0.00 | sell |
| Schonfeld Strategic Advisors LLC | 0 | 26,362 | +26,362 | 0.00 | 0.00 | +0.00 | buy |
| OSAIC HOLDINGS, INC. | 27,317 | 25,631 | -1,686 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 24,767 | 24,941 | +174 | 0.00 | 0.00 | -0.00 | buy |
| Louisiana State Employees Retirement System | 23,200 | 23,100 | -100 | 0.01 | 0.01 | -0.00 | sell |
| HRT FINANCIAL LP | 0 | 22,720 | +22,720 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 21,234 | 22,168 | +934 | 0.00 | 0.00 | -0.00 | buy |
| Brevan Howard Capital Management LP | 0 | 21,885 | +21,885 | 0.00 | 0.00 | +0.00 | buy |
| State of Tennessee, Department of Treasury | 29,064 | 21,682 | -7,382 | 0.00 | 0.00 | -0.00 | sell |
| INTECH INVESTMENT MANAGEMENT LLC | 22,864 | 21,134 | -1,730 | 0.00 | 0.00 | -0.00 | sell |
| Linden Thomas Advisory Services, LLC | 20,978 | 20,709 | -269 | 0.05 | 0.04 | -0.01 | sell |
| AXQ CAPITAL, LP | 0 | 20,650 | +20,650 | 0.00 | 0.11 | +0.11 | buy |
| Hedges Asset Management LLC | 20,000 | 20,000 | 0 | 0.23 | 0.27 | +0.04 | hold |
| AMERICAN CENTURY COMPANIES INC | 0 | 19,457 | +19,457 | 0.00 | 0.00 | +0.00 | buy |
| JANUS HENDERSON GROUP PLC | 18,934 | 18,934 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Williams Jones Wealth Management, LLC. | 18,900 | 18,900 | 0 | 0.00 | 0.00 | -0.00 | hold |
| YOUSIF CAPITAL MANAGEMENT, LLC | 18,863 | 18,814 | -49 | 0.00 | 0.00 | -0.00 | sell |
| COMERICA BANK | 17,250 | 16,785 | -465 | 0.00 | 0.00 | -0.00 | sell |
| Atika Capital Management LLC | 0 | 16,400 | +16,400 | 0.00 | 0.03 | +0.03 | buy |
| TEXAS PERMANENT SCHOOL FUND CORP | 19,416 | 16,104 | -3,312 | 0.00 | 0.00 | -0.00 | sell |
| Creative Planning | 13,089 | 15,695 | +2,606 | 0.00 | 0.00 | +0.00 | buy |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 15,297 | 15,297 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RAYMOND JAMES FINANCIAL INC | 12,293 | 15,276 | +2,983 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 3,789 | 15,268 | +11,479 | 0.00 | 0.00 | +0.00 | buy |
| Maryland State Retirement & Pension System | 14,363 | 14,363 | 0 | 0.01 | 0.01 | -0.00 | hold |
| AMALGAMATED BANK | 14,095 | 14,095 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 14,076 | 14,076 | 0 | 0.00 | 0.00 | -0.00 | hold |
| VOYA INVESTMENT MANAGEMENT LLC | 13,395 | 13,829 | +434 | 0.00 | 0.00 | -0.00 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 13,791 | 13,791 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SG Americas Securities, LLC | 49,072 | 13,723 | -35,349 | 0.00 | 0.00 | -0.00 | sell |
| QUADRANT CAPITAL GROUP LLC | 12,902 | 12,813 | -89 | 0.01 | 0.01 | -0.00 | sell |