| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Commodore Capital LP | 0 | 3,200,000 | +3,200,000 | 0.00 | 4.28 | +4.28 | buy |
| Kynam Capital Management, LP | 5,064,207 | 6,500,000 | +1,435,793 | 8.44 | 10.09 | +1.65 | buy |
| UBS Group AG | 389,797 | 1,468,240 | +1,078,443 | 0.00 | 0.01 | +0.00 | buy |
| FMR LLC | 4,857,668 | 5,380,091 | +522,423 | 0.01 | 0.01 | -0.00 | buy |
| Deep Track Capital, LP | 1,540,132 | 2,000,000 | +459,868 | 1.46 | 1.18 | -0.28 | buy |
| Fisher Asset Management, LLC | 452,497 | 871,628 | +419,131 | 0.00 | 0.01 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 93,602 | 399,932 | +306,330 | 0.00 | 0.01 | +0.01 | buy |
| NATIXIS | 15,800 | 232,188 | +216,388 | 0.00 | 0.02 | +0.02 | buy |
| BANK OF AMERICA CORP /DE/ | 42,848 | 244,936 | +202,088 | 0.00 | 0.00 | +0.00 | buy |
| Novo Holdings A/S | 1,000,000 | 1,200,000 | +200,000 | 1.53 | 1.66 | +0.13 | buy |
| JPMORGAN CHASE & CO | 85,545 | 241,354 | +155,809 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 85,582 | 214,426 | +128,844 | 0.00 | 0.01 | +0.00 | buy |
| TSP Capital Management Group, LLC | 223,343 | 335,977 | +112,634 | 1.92 | 2.01 | +0.09 | buy |
| Point72 Asset Management, L.P. | 2,515,972 | 2,621,175 | +105,203 | 0.17 | 0.13 | -0.04 | buy |
| Walleye Capital LLC | 0 | 93,327 | +93,327 | 0.00 | 0.02 | +0.02 | buy |
| Trexquant Investment LP | 0 | 78,210 | +78,210 | 0.00 | 0.02 | +0.02 | buy |
| TFG Asset Management GP Ltd | 192,000 | 261,000 | +69,000 | 1.57 | 1.52 | -0.05 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 62,326 | +62,326 | 0.00 | 0.10 | +0.10 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,534,916 | 1,589,806 | +54,890 | 0.00 | 0.00 | -0.00 | buy |
| BlackRock, Inc. | 5,480,670 | 5,524,132 | +43,462 | 0.00 | 0.00 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 62,631 | 105,140 | +42,509 | 0.00 | 0.00 | +0.00 | buy |
| SPHERA FUNDS MANAGEMENT LTD. | 474,103 | 507,829 | +33,726 | 2.21 | 2.27 | +0.06 | buy |
| ALGERT GLOBAL LLC | 104,337 | 133,597 | +29,260 | 0.06 | 0.06 | -0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 66,034 | 93,670 | +27,636 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 21,418 | +21,418 | 0.00 | 0.00 | +0.00 | buy |
| PDT Partners, LLC | 0 | 20,899 | +20,899 | 0.00 | 0.03 | +0.03 | buy |
| BANK OF MONTREAL /CAN/ | 0 | 19,607 | +19,607 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 0 | 18,396 | +18,396 | 0.00 | 0.00 | +0.00 | buy |
| Apella Capital, LLC | 0 | 17,000 | +17,000 | 0.00 | 0.01 | +0.01 | buy |
| AMERICAN CENTURY COMPANIES INC | 608,457 | 625,321 | +16,864 | 0.01 | 0.01 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 121,501 | 138,289 | +16,788 | 0.00 | 0.00 | -0.00 | buy |
| VANGUARD GROUP INC | 3,881,995 | 3,898,435 | +16,440 | 0.00 | 0.00 | -0.00 | buy |
| Campbell & CO Investment Adviser LLC | 0 | 15,530 | +15,530 | 0.00 | 0.02 | +0.02 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 116,317 | 131,296 | +14,979 | 0.00 | 0.00 | -0.00 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0 | 14,834 | +14,834 | 0.00 | 0.00 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 0 | 14,600 | +14,600 | 0.00 | 0.05 | +0.05 | buy |
| CIBC WORLD MARKETS CORP | 0 | 14,333 | +14,333 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 119,359 | 130,688 | +11,329 | 0.00 | 0.00 | -0.00 | buy |
| Invesco Ltd. | 42,101 | 52,443 | +10,342 | 0.00 | 0.00 | -0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 136,588 | 146,588 | +10,000 | 0.01 | 0.00 | -0.00 | buy |
| Atom Investors LP | 39,203 | 49,179 | +9,976 | 0.12 | 0.11 | -0.01 | buy |
| SG Americas Securities, LLC | 25,283 | 34,884 | +9,601 | 0.00 | 0.00 | -0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 23,290 | 32,670 | +9,380 | 0.11 | 0.09 | -0.02 | buy |
| Point72 (DIFC) Ltd | 0 | 8,446 | +8,446 | 0.00 | 0.01 | +0.01 | buy |
| Mirador Capital Partners LP | 119,492 | 127,874 | +8,382 | 0.55 | 0.41 | -0.14 | buy |
| AlphaQuest LLC | 4,287 | 12,112 | +7,825 | 0.01 | 0.02 | +0.01 | buy |
| RHUMBLINE ADVISERS | 91,939 | 98,266 | +6,327 | 0.00 | 0.00 | -0.00 | buy |
| Virtus Investment Advisers, LLC | 0 | 6,208 | +6,208 | 0.00 | 0.03 | +0.03 | buy |
| Aquatic Capital Management LLC | 4,780 | 10,976 | +6,196 | 0.00 | 0.01 | +0.00 | buy |
| Engineers Gate Manager LP | 11,489 | 15,402 | +3,913 | 0.01 | 0.00 | -0.00 | buy |
| Creative Planning | 19,854 | 23,669 | +3,815 | 0.00 | 0.00 | -0.00 | buy |
| TWINBEECH CAPITAL LP | 34,558 | 38,344 | +3,786 | 0.01 | 0.01 | -0.00 | buy |
| Jump Financial, LLC | 16,513 | 19,248 | +2,735 | 0.01 | 0.01 | -0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 32,545 | 35,141 | +2,596 | 0.01 | 0.01 | -0.00 | buy |
| DnB Asset Management AS | 10,131 | 12,634 | +2,503 | 0.00 | 0.00 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 2,038 | +2,038 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 1,798 | +1,798 | 0.00 | 0.01 | +0.01 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 3,753,260 | 3,754,793 | +1,533 | 1.73 | 1.36 | -0.37 | buy |
| Aster Capital Management (DIFC) Ltd | 190 | 1,446 | +1,256 | 0.00 | 0.01 | +0.00 | buy |
| Nebula Research & Development LLC | 14,027 | 15,169 | +1,142 | 0.04 | 0.03 | -0.02 | buy |
| GUGGENHEIM CAPITAL LLC | 23,797 | 24,783 | +986 | 0.00 | 0.00 | -0.00 | buy |
| Values First Advisors, Inc. | 29,009 | 29,933 | +924 | 0.40 | 0.32 | -0.08 | buy |
| WELLS FARGO & COMPANY/MN | 32,498 | 33,378 | +880 | 0.00 | 0.00 | -0.00 | buy |
| Parallel Advisors, LLC | 79 | 933 | +854 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 42,771 | 43,451 | +680 | 0.00 | 0.00 | -0.00 | buy |
| Ensign Peak Advisors, Inc | 23,428 | 24,078 | +650 | 0.00 | 0.00 | -0.00 | buy |
| SIGNATUREFD, LLC | 257 | 561 | +304 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 33,935 | 34,221 | +286 | 0.01 | 0.01 | -0.00 | buy |
| QUADRANT CAPITAL GROUP LLC | 67 | 334 | +267 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 1,285 | 1,438 | +153 | 0.00 | 0.00 | -0.00 | buy |
| Private Wealth Management Group, LLC | 0 | 126 | +126 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 44 | 164 | +120 | 0.00 | 0.00 | +0.00 | buy |
| SIERRA OCEAN, LLC | 0 | 92 | +92 | 0.00 | 0.00 | +0.00 | buy |
| Versant Capital Management, Inc | 0 | 88 | +88 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 62 | 107 | +45 | 0.00 | 0.00 | -0.00 | buy |
| Parkside Financial Bank & Trust | 0 | 40 | +40 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 0 | 32 | +32 | 0.00 | 0.00 | +0.00 | buy |
| Hughes Financial Services, LLC | 0 | 24 | +24 | 0.00 | 0.00 | +0.00 | buy |
| Blue Trust, Inc. | 0 | 23 | +23 | 0.00 | 0.00 | +0.00 | buy |
| Stephens Consulting, LLC | 0 | 20 | +20 | 0.00 | 0.00 | +0.00 | buy |
| J.Safra Asset Management Corp | 312 | 330 | +18 | 0.00 | 0.00 | -0.00 | buy |
| SBI Securities Co., Ltd. | 30 | 46 | +16 | 0.00 | 0.00 | +0.00 | buy |
| COMERICA BANK | 0 | 15 | +15 | 0.00 | 0.00 | +0.00 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 12 | +12 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 18 | 29 | +11 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 1,805 | 1,814 | +9 | 0.00 | 0.00 | -0.00 | buy |
| AMALGAMATED BANK | 2,182 | 2,189 | +7 | 0.00 | 0.00 | -0.00 | buy |
| Amundi | 42 | 45 | +3 | 0.00 | 0.00 | -0.00 | buy |
| Covestor Ltd | 6 | 9 | +3 | 0.00 | 0.00 | 0.00 | buy |
| CANADA LIFE ASSURANCE Co | 6,338 | 6,338 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NOMURA ASSET MANAGEMENT CO LTD | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Ameritas Investment Partners, Inc. | 6,544 | 6,544 | 0 | 0.01 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 56,170 | 56,170 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 48,099 | 48,099 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 65,540 | 65,540 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BAKER BROS. ADVISORS LP | 247,644 | 247,644 | 0 | 0.07 | 0.05 | -0.02 | hold |
| JANUS HENDERSON GROUP PLC | 25,642 | 25,642 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CIBC Private Wealth Group LLC | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 15,930 | 15,930 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Handelsbanken Fonder AB | 21,100 | 21,100 | 0 | 0.00 | 0.00 | -0.00 | hold |