| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| OCCUDO QUANTITATIVE STRATEGIES LP | 0 | 20,925 | +20,925 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 170,049 | 181,603 | +11,554 | 0.00 | 0.00 | -0.00 | buy |
| VANGUARD GROUP INC | 405,533 | 416,149 | +10,616 | 0.00 | 0.00 | -0.00 | buy |
| MORGAN STANLEY | 159,183 | 167,116 | +7,933 | 0.00 | 0.00 | -0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 19,560 | 21,837 | +2,277 | 0.00 | 0.00 | -0.00 | buy |
| CITADEL ADVISORS LLC | 15,210 | 17,473 | +2,263 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 138,949 | 141,103 | +2,154 | 0.00 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 60,688 | 62,656 | +1,968 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 420 | 2,281 | +1,861 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 8,361 | 9,695 | +1,334 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 500 | +500 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 0 | 435 | +435 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 3,960 | 4,371 | +411 | 0.00 | 0.00 | -0.00 | buy |
| CITIGROUP INC | 1,371 | 1,768 | +397 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 2,778 | 3,119 | +341 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 531 | 852 | +321 | 0.00 | 0.00 | +0.00 | buy |
| Woodline Partners LP | 72,106 | 72,211 | +105 | 0.02 | 0.02 | +0.00 | buy |
| NewEdge Advisors, LLC | 0 | 60 | +60 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 8 | 23 | +15 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 587 | 600 | +13 | 0.00 | 0.00 | -0.00 | buy |
| Allspring Global Investments Holdings, LLC | 15 | 19 | +4 | 0.00 | 0.00 | +0.00 | buy |
| MATHER GROUP, LLC. | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| TD Waterhouse Canada Inc. | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 604 | 604 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BVF INC/IL | 3,633,743 | 3,633,743 | 0 | 2.40 | 2.41 | +0.01 | hold |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 26,400 | 26,400 | 0 | 0.01 | 0.01 | +0.00 | hold |
| RBF Capital, LLC | 30,616 | 30,616 | 0 | 0.04 | 0.04 | +0.00 | hold |
| NATIXIS | 1,726 | 1,726 | 0 | 0.00 | 0.00 | +0.00 | hold |
| HighVista Strategies LLC | 118,899 | 118,899 | 0 | 1.02 | 1.03 | +0.01 | hold |
| MACQUARIE GROUP LTD | 3,466 | 3,466 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Acuitas Investments, LLC | 123,197 | 123,197 | 0 | 1.49 | 1.56 | +0.07 | hold |
| Opaleye Management Inc. | 250,000 | 250,000 | 0 | 1.31 | 1.35 | +0.04 | hold |
| Avior Wealth Management, LLC | 501 | 501 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Global Retirement Partners, LLC | 600 | 600 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TLS Advisors LLC | 120,365 | 120,365 | 0 | 6.74 | 7.14 | +0.40 | hold |
| CM Management, LLC | 55,000 | 55,000 | 0 | 1.11 | 1.20 | +0.08 | hold |
| Knott David M Jr | 19,722 | 19,722 | 0 | 0.17 | 0.19 | +0.02 | hold |
| GAMMA Investing LLC | 75 | 75 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PRICE T ROWE ASSOCIATES INC /MD/ | 8,778 | 8,778 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 247 | 247 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Covestor Ltd | 16 | 0 | -16 | 0.00 | 0.00 | 0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 735 | 582 | -153 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 5,638 | 5,262 | -376 | 0.00 | 0.00 | -0.00 | sell |
| Truvestments Capital LLC | 400 | 0 | -400 | 0.00 | 0.00 | -0.00 | sell |
| METROPOLITAN LIFE INSURANCE CO/NY | 411 | 0 | -411 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 5,161 | 2,809 | -2,352 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 3,543 | 837 | -2,706 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 25,516 | 22,414 | -3,102 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN INTERNATIONAL GROUP, INC. | 3,603 | 0 | -3,603 | 0.00 | 0.00 | -0.00 | sell |
| Stonepine Capital Management, LLC | 253,770 | 250,129 | -3,641 | 4.84 | 5.41 | +0.56 | sell |
| NORTHERN TRUST CORP | 86,096 | 82,198 | -3,898 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 4,636 | 12 | -4,624 | 0.00 | 0.00 | -0.00 | sell |
| FIRST MANHATTAN CO. LLC. | 5,000 | 0 | -5,000 | 0.00 | 0.00 | -0.00 | sell |
| Eversept Partners, LP | 97,065 | 91,907 | -5,158 | 0.17 | 0.17 | -0.01 | sell |
| FMR LLC | 1,160,600 | 1,153,404 | -7,196 | 0.00 | 0.00 | -0.00 | sell |
| UBS Group AG | 7,355 | 0 | -7,355 | 0.00 | 0.00 | -0.00 | sell |