| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Woodline Partners LP | 72,211 | 95,339 | +23,128 | 0.02 | 0.02 | +0.00 | buy |
| Ellsworth Advisors, LLC | 0 | 19,475 | +19,475 | 0.00 | 0.13 | +0.13 | buy |
| MORGAN STANLEY | 167,116 | 182,852 | +15,736 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 15,293 | +15,293 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 0 | 14,624 | +14,624 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 14,441 | +14,441 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 13,339 | +13,339 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 8,481 | +8,481 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 2,809 | 11,256 | +8,447 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 82,198 | 89,841 | +7,643 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 416,149 | 422,394 | +6,245 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 1,768 | 7,030 | +5,262 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 0 | 4,883 | +4,883 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 0 | 3,567 | +3,567 | 0.00 | 0.00 | +0.00 | buy |
| Eversept Partners, LP | 91,907 | 94,289 | +2,382 | 0.17 | 0.19 | +0.02 | buy |
| STATE STREET CORP | 141,103 | 142,857 | +1,754 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 181,603 | 182,741 | +1,138 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 3,254 | 4,368 | +1,114 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 837 | 1,632 | +795 | 0.00 | 0.00 | +0.00 | buy |
| Truvestments Capital LLC | 0 | 290 | +290 | 0.00 | 0.00 | +0.00 | buy |
| Allspring Global Investments Holdings, LLC | 19 | 231 | +212 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 12 | 124 | +112 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 40 | +40 | 0.00 | 0.00 | +0.00 | buy |
| EARNED WEALTH ADVISORS, LLC | 0 | 25 | +25 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 75 | 95 | +20 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 600 | 617 | +17 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 604 | 604 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BVF INC/IL | 3,633,743 | 3,633,743 | 0 | 2.41 | 2.81 | +0.40 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 582 | 582 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 26,400 | 26,400 | 0 | 0.01 | 0.02 | +0.00 | hold |
| RBF Capital, LLC | 30,616 | 30,616 | 0 | 0.04 | 0.04 | -0.00 | hold |
| NATIXIS | 1,726 | 1,726 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MACQUARIE GROUP LTD | 3,466 | 3,466 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MetLife Investment Management, LLC | 4,371 | 4,371 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Opaleye Management Inc. | 250,000 | 250,000 | 0 | 1.35 | 1.10 | -0.25 | hold |
| Avior Wealth Management, LLC | 501 | 501 | 0 | 0.00 | 0.00 | +0.00 | hold |
| OCCUDO QUANTITATIVE STRATEGIES LP | 20,925 | 20,925 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CM Management, LLC | 55,000 | 55,000 | 0 | 1.20 | 1.16 | -0.03 | hold |
| Knott David M Jr | 19,722 | 19,722 | 0 | 0.19 | 0.18 | -0.00 | hold |
| TD Waterhouse Canada Inc. | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DIMENSIONAL FUND ADVISORS LP | 22,414 | 22,414 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Legal & General Group Plc | 852 | 852 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 21,837 | 21,837 | 0 | 0.00 | 0.00 | +0.00 | hold |
| AMALGAMATED BANK | 247 | 247 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MATHER GROUP, LLC. | 1 | 0 | -1 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 3,119 | 3,117 | -2 | 0.00 | 0.00 | +0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 23 | 17 | -6 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 4,320 | 4,293 | -27 | 0.00 | 0.00 | +0.00 | sell |
| NewEdge Advisors, LLC | 60 | 0 | -60 | 0.00 | 0.00 | -0.00 | sell |
| GROUP ONE TRADING LLC | 500 | 400 | -100 | 0.00 | 0.00 | +0.00 | sell |
| Russell Investments Group, Ltd. | 435 | 316 | -119 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 9,695 | 9,366 | -329 | 0.00 | 0.00 | +0.00 | sell |
| Global Retirement Partners, LLC | 600 | 0 | -600 | 0.00 | 0.00 | -0.00 | sell |
| TLS Advisors LLC | 120,365 | 119,744 | -621 | 7.14 | 6.70 | -0.44 | sell |
| Tower Research Capital LLC (TRC) | 2,281 | 556 | -1,725 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 5,262 | 1,562 | -3,700 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 17,473 | 13,505 | -3,968 | 0.00 | 0.00 | -0.00 | sell |
| HighVista Strategies LLC | 118,899 | 114,548 | -4,351 | 1.03 | 1.05 | +0.02 | sell |
| Bank of New York Mellon Corp | 62,656 | 57,547 | -5,109 | 0.00 | 0.00 | +0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 8,778 | 0 | -8,778 | 0.00 | 0.00 | -0.00 | sell |
| Acuitas Investments, LLC | 123,197 | 88,058 | -35,139 | 1.56 | 1.04 | -0.52 | sell |
| FMR LLC | 1,153,404 | 1,102,401 | -51,003 | 0.00 | 0.00 | +0.00 | sell |
| Stonepine Capital Management, LLC | 250,129 | 195,096 | -55,033 | 5.41 | 3.26 | -2.14 | sell |