| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| First Light Asset Management, LLC | 3,344,033 | 4,090,296 | +746,263 | 2.12 | 4.77 | +2.65 | buy |
| Soleus Capital Management, L.P. | 3,305,815 | 3,005,943 | -299,872 | 2.11 | 3.50 | +1.39 | sell |
| MORGAN STANLEY | 2,520,388 | 2,900,413 | +380,025 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 2,411,916 | 2,425,789 | +13,873 | 0.00 | 0.00 | +0.00 | buy |
| ArrowMark Colorado Holdings LLC | 5,116,551 | 2,275,463 | -2,841,088 | 0.44 | 0.41 | -0.03 | sell |
| Assenagon Asset Management S.A. | 1,310,811 | 1,311,106 | +295 | 0.02 | 0.04 | +0.01 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 978,896 | 1,010,508 | +31,612 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 681,755 | 959,592 | +277,837 | 0.00 | 0.01 | +0.01 | buy |
| DAFNA Capital Management LLC | 935,894 | 935,894 | 0 | 1.62 | 3.10 | +1.48 | hold |
| STATE STREET CORP | 801,623 | 896,674 | +95,051 | 0.00 | 0.00 | +0.00 | buy |
| TOCQUEVILLE ASSET MANAGEMENT L.P. | 769,900 | 694,900 | -75,000 | 0.09 | 0.15 | +0.06 | sell |
| DIMENSIONAL FUND ADVISORS LP | 614,165 | 680,768 | +66,603 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 608,585 | 634,344 | +25,759 | 0.01 | 0.01 | +0.01 | buy |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 800,921 | 589,305 | -211,616 | 0.04 | 0.06 | +0.02 | sell |
| DEUTSCHE BANK AG\ | 574,725 | 582,239 | +7,514 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 0 | 549,000 | +549,000 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 470,661 | 489,137 | +18,476 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 331,285 | 433,985 | +102,700 | 0.00 | 0.01 | +0.00 | buy |
| Parkman Healthcare Partners LLC | 0 | 412,888 | +412,888 | 0.00 | 0.74 | +0.74 | buy |
| ARMISTICE CAPITAL, LLC | 0 | 400,055 | +400,055 | 0.00 | 0.15 | +0.15 | buy |
| NORTHERN TRUST CORP | 365,337 | 377,289 | +11,952 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 335,105 | 363,764 | +28,659 | 0.00 | 0.00 | +0.00 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 0 | 358,860 | +358,860 | 0.00 | 0.04 | +0.04 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 185,568 | 308,686 | +123,118 | 0.01 | 0.02 | +0.02 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 283,749 | +283,749 | 0.00 | 0.03 | +0.03 | buy |
| PERKINS CAPITAL MANAGEMENT INC | 289,349 | 283,399 | -5,950 | 1.97 | 3.73 | +1.75 | sell |
| GOLDMAN SACHS GROUP INC | 192,487 | 281,953 | +89,466 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 44,561 | 277,486 | +232,925 | 0.00 | 0.00 | +0.00 | buy |
| OBERWEIS ASSET MANAGEMENT INC/ | 0 | 228,000 | +228,000 | 0.00 | 0.16 | +0.16 | buy |
| Nicholas Investment Partners, LP | 0 | 197,135 | +197,135 | 0.00 | 0.25 | +0.25 | buy |
| Birchview Capital, LP | 197,000 | 197,000 | 0 | 1.32 | 2.39 | +1.07 | hold |
| PANAGORA ASSET MANAGEMENT INC | 292,214 | 194,172 | -98,042 | 0.01 | 0.01 | +0.00 | sell |
| RICE HALL JAMES & ASSOCIATES, LLC | 194,269 | 192,180 | -2,089 | 0.08 | 0.15 | +0.06 | sell |
| FMR LLC | 21,227 | 178,957 | +157,730 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 231,905 | 156,564 | -75,341 | 0.00 | 0.00 | +0.00 | sell |
| KENNEDY CAPITAL MANAGEMENT LLC | 293,536 | 145,349 | -148,187 | 0.05 | 0.04 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 90,092 | 143,613 | +53,521 | 0.01 | 0.03 | +0.02 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 137,575 | 141,663 | +4,088 | 0.03 | 0.05 | +0.02 | buy |
| Bank of New York Mellon Corp | 160,892 | 131,450 | -29,442 | 0.00 | 0.00 | +0.00 | sell |
| WHITE PINE CAPITAL LLC | 116,312 | 121,382 | +5,070 | 0.32 | 0.58 | +0.26 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 112,352 | +112,352 | 0.00 | 0.02 | +0.02 | buy |
| MARSHALL WACE, LLP | 0 | 110,354 | +110,354 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 182,252 | 94,761 | -87,491 | 0.00 | 0.00 | -0.00 | sell |
| Engineers Gate Manager LP | 129,433 | 89,337 | -40,096 | 0.02 | 0.02 | +0.00 | sell |
| BRADLEY FOSTER & SARGENT INC/CT | 0 | 81,164 | +81,164 | 0.00 | 0.02 | +0.02 | buy |
| NORGES BANK | 148,300 | 77,000 | -71,300 | 0.00 | 0.00 | -0.00 | sell |
| FRANKLIN RESOURCES INC | 69,281 | 76,048 | +6,767 | 0.00 | 0.00 | +0.00 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 147,458 | 74,742 | -72,716 | 0.03 | 0.02 | -0.00 | sell |
| STONE RUN CAPITAL, LLC | 23,000 | 73,500 | +50,500 | 0.07 | 0.38 | +0.32 | buy |
| BARCLAYS PLC | 32,854 | 72,036 | +39,182 | 0.00 | 0.00 | +0.00 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 0 | 70,992 | +70,992 | 0.00 | 0.00 | +0.00 | buy |
| Informed Momentum Co LLC | 0 | 70,076 | +70,076 | 0.00 | 0.15 | +0.15 | buy |
| Qube Research & Technologies Ltd | 0 | 66,935 | +66,935 | 0.00 | 0.00 | +0.00 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 85,107 | 58,930 | -26,177 | 0.00 | 0.00 | +0.00 | sell |
| GLOBEFLEX CAPITAL L P | 0 | 58,497 | +58,497 | 0.00 | 0.08 | +0.08 | buy |
| JANE STREET GROUP, LLC | 73,262 | 57,116 | -16,146 | 0.00 | 0.00 | +0.00 | sell |
| RHUMBLINE ADVISERS | 58,157 | 56,711 | -1,446 | 0.00 | 0.00 | +0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 47,377 | 55,534 | +8,157 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 55,330 | 55,330 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Jump Financial, LLC | 0 | 53,561 | +53,561 | 0.00 | 0.02 | +0.02 | buy |
| Aquatic Capital Management LLC | 7,100 | 47,900 | +40,800 | 0.00 | 0.02 | +0.02 | buy |
| Trexquant Investment LP | 11,262 | 45,905 | +34,643 | 0.00 | 0.01 | +0.01 | buy |
| FULLER & THALER ASSET MANAGEMENT, INC. | 0 | 44,625 | +44,625 | 0.00 | 0.00 | +0.00 | buy |
| Semanteon Capital Management, LP | 0 | 43,016 | +43,016 | 0.00 | 0.41 | +0.41 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 14,249 | 42,528 | +28,279 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 28,986 | 40,860 | +11,874 | 0.00 | 0.00 | +0.00 | buy |
| BOSUN ASSET MANAGEMENT, LLC | 0 | 35,638 | +35,638 | 0.00 | 0.24 | +0.24 | buy |
| ROYAL BANK OF CANADA | 28,602 | 35,245 | +6,643 | 0.00 | 0.00 | +0.00 | buy |
| M&T BANK CORP | 70,508 | 34,682 | -35,826 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 31,173 | 31,600 | +427 | 0.00 | 0.00 | +0.00 | buy |
| Empire Financial Management Company, LLC | 52,500 | 31,000 | -21,500 | 0.13 | 0.13 | +0.01 | sell |
| CITIGROUP INC | 9,231 | 30,751 | +21,520 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 60,913 | 29,815 | -31,098 | 0.00 | 0.00 | -0.00 | sell |
| Creative Planning | 11,810 | 29,790 | +17,980 | 0.00 | 0.00 | +0.00 | buy |
| Centiva Capital, LP | 30,426 | 26,871 | -3,555 | 0.01 | 0.02 | +0.01 | sell |
| Corton Capital Inc. | 25,220 | 26,588 | +1,368 | 0.10 | 0.18 | +0.09 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 26,393 | +26,393 | 0.00 | 0.00 | +0.00 | buy |
| Divisadero Street Capital Management, LP | 686,994 | 26,272 | -660,722 | 0.81 | 0.05 | -0.77 | sell |
| WELLS FARGO & COMPANY/MN | 47,807 | 26,007 | -21,800 | 0.00 | 0.00 | -0.00 | sell |
| OCCUDO QUANTITATIVE STRATEGIES LP | 0 | 25,946 | +25,946 | 0.00 | 0.07 | +0.07 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 16,700 | 25,213 | +8,513 | 0.00 | 0.00 | +0.00 | buy |
| Legato Capital Management LLC | 0 | 24,180 | +24,180 | 0.00 | 0.04 | +0.04 | buy |
| MetLife Investment Management, LLC | 23,715 | 23,715 | 0 | 0.00 | 0.00 | +0.00 | hold |
| HSBC HOLDINGS PLC | 30,332 | 23,643 | -6,689 | 0.00 | 0.00 | +0.00 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 21,151 | 23,202 | +2,051 | 0.00 | 0.00 | +0.00 | buy |
| Corebridge Financial, Inc. | 22,813 | 22,672 | -141 | 0.00 | 0.00 | +0.00 | sell |
| ALGERT GLOBAL LLC | 0 | 22,390 | +22,390 | 0.00 | 0.01 | +0.01 | buy |
| UNITED CAPITAL FINANCIAL ADVISORS, LLC | 21,251 | 21,225 | -26 | 0.00 | 0.00 | +0.00 | sell |
| Jefferies Financial Group Inc. | 0 | 20,666 | +20,666 | 0.00 | 0.00 | +0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 0 | 19,870 | +19,870 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 0 | 19,108 | +19,108 | 0.00 | 0.00 | +0.00 | buy |
| PAX Financial Group, LLC | 18,884 | 18,884 | 0 | 0.03 | 0.05 | +0.02 | hold |
| ACADIAN ASSET MANAGEMENT LLC | 17,414 | 17,378 | -36 | 0.00 | 0.00 | +0.00 | sell |
| SENTRY INVESTMENT MANAGEMENT LLC | 15,885 | 17,368 | +1,483 | 0.05 | 0.10 | +0.05 | buy |
| Point72 Asset Management, L.P. | 0 | 17,100 | +17,100 | 0.00 | 0.00 | +0.00 | buy |
| MAIRS & POWER INC | 17,000 | 17,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 16,933 | 16,933 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 17,023 | 16,555 | -468 | 0.00 | 0.00 | +0.00 | sell |
| SG Americas Securities, LLC | 0 | 16,187 | +16,187 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 0 | 14,772 | +14,772 | 0.00 | 0.00 | +0.00 | buy |