| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Rosalind Advisors, Inc. | 3,300,389 | 3,300,389 | 0 | 15.97 | 11.66 | -4.31 | hold |
| BlackRock, Inc. | 1,717,197 | 1,768,954 | +51,757 | 0.00 | 0.00 | -0.00 | buy |
| VANGUARD GROUP INC | 1,610,735 | 1,657,428 | +46,693 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 703,171 | 687,613 | -15,558 | 0.00 | 0.00 | -0.00 | sell |
| Nantahala Capital Management, LLC | 0 | 666,435 | +666,435 | 0.00 | 0.44 | +0.44 | buy |
| STATE STREET CORP | 473,893 | 621,250 | +147,357 | 0.00 | 0.00 | -0.00 | buy |
| Vivo Capital, LLC | 569,526 | 569,526 | 0 | 0.79 | 0.49 | -0.30 | hold |
| Divisadero Street Capital Management, LP | 0 | 476,160 | +476,160 | 0.00 | 0.24 | +0.24 | buy |
| CITADEL ADVISORS LLC | 803,208 | 449,315 | -353,893 | 0.01 | 0.00 | -0.01 | sell |
| Propel Bio Management, LLC | 226,052 | 438,509 | +212,457 | 3.73 | 4.72 | +0.99 | buy |
| Ikarian Capital, LLC | 322,390 | 431,251 | +108,861 | 1.45 | 0.94 | -0.51 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 319,047 | 413,820 | +94,773 | 0.10 | 0.10 | -0.01 | buy |
| ExodusPoint Capital Management, LP | 0 | 379,583 | +379,583 | 0.00 | 0.06 | +0.06 | buy |
| MARSHALL WACE, LLP | 483,259 | 288,763 | -194,496 | 0.01 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 203,191 | 279,160 | +75,969 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 153,554 | 272,095 | +118,541 | 0.00 | 0.00 | +0.00 | buy |
| Palisades Investment Partners, LLC | 270,310 | 262,942 | -7,368 | 1.61 | 1.11 | -0.50 | sell |
| Simplify Asset Management Inc. | 106,629 | 261,126 | +154,497 | 0.09 | 0.06 | -0.03 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 178,000 | 256,200 | +78,200 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 457,440 | 253,015 | -204,425 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 272,324 | 252,727 | -19,597 | 0.00 | 0.00 | -0.00 | sell |
| APIS CAPITAL ADVISORS, LLC | 205,000 | 246,000 | +41,000 | 0.99 | 0.58 | -0.41 | buy |
| MILLENNIUM MANAGEMENT LLC | 249,755 | 239,254 | -10,501 | 0.00 | 0.00 | -0.00 | sell |
| ADAR1 Capital Management, LLC | 149,385 | 224,385 | +75,000 | 0.33 | 0.24 | -0.09 | buy |
| JANE STREET GROUP, LLC | 206,783 | 219,260 | +12,477 | 0.00 | 0.00 | -0.00 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 103,026 | 203,386 | +100,360 | 0.29 | 0.32 | +0.03 | buy |
| CIBC WORLD MARKET INC. | 146,610 | 178,510 | +31,900 | 0.00 | 0.00 | -0.00 | buy |
| Private Wealth Advisors, LLC | 168,596 | 156,283 | -12,313 | 0.90 | 0.63 | -0.27 | sell |
| HRT FINANCIAL LP | 0 | 155,082 | +155,082 | 0.00 | 0.01 | +0.01 | buy |
| Cubist Systematic Strategies, LLC | 306,300 | 145,350 | -160,950 | 0.05 | 0.02 | -0.02 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 119,262 | 119,262 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Trexquant Investment LP | 102,647 | 118,780 | +16,133 | 0.02 | 0.01 | -0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 47,035 | 116,112 | +69,077 | 0.02 | 0.03 | +0.01 | buy |
| UBS Group AG | 56,891 | 114,831 | +57,940 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 126,500 | 110,641 | -15,859 | 0.00 | 0.00 | -0.00 | sell |
| RAYMOND JAMES FINANCIAL INC | 42,816 | 86,761 | +43,945 | 0.00 | 0.00 | +0.00 | buy |
| Diametric Capital, LP | 0 | 86,227 | +86,227 | 0.00 | 0.34 | +0.34 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 88,858 | 85,621 | -3,237 | 0.00 | 0.00 | -0.00 | sell |
| Capital Advisors Wealth Management, LLC | 76,000 | 85,500 | +9,500 | 0.16 | 0.13 | -0.03 | buy |
| Bank of New York Mellon Corp | 66,035 | 69,429 | +3,394 | 0.00 | 0.00 | -0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 98,359 | 67,506 | -30,853 | 0.01 | 0.00 | -0.00 | sell |
| Nuveen, LLC | 118,878 | 66,358 | -52,520 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 74,677 | 65,128 | -9,549 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 22,250 | 62,147 | +39,897 | 0.00 | 0.00 | +0.00 | buy |
| AWM Investment Company, Inc. | 0 | 57,721 | +57,721 | 0.00 | 0.06 | +0.06 | buy |
| BARCLAYS PLC | 53,783 | 55,996 | +2,213 | 0.00 | 0.00 | -0.00 | buy |
| AMERIPRISE FINANCIAL INC | 28,363 | 43,237 | +14,874 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 43,064 | 42,508 | -556 | 0.00 | 0.00 | -0.00 | sell |
| Brooklyn Investment Group | 0 | 42,115 | +42,115 | 0.00 | 0.05 | +0.05 | buy |
| Tripletail Wealth Management, LLC | 41,165 | 36,825 | -4,340 | 0.60 | 0.49 | -0.12 | sell |
| Verition Fund Management LLC | 57,579 | 35,838 | -21,741 | 0.00 | 0.00 | -0.00 | sell |
| GILDER GAGNON HOWE & CO LLC | 33,133 | 35,819 | +2,686 | 0.00 | 0.00 | -0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 16,790 | 33,334 | +16,544 | 0.02 | 0.03 | +0.01 | buy |
| Graham Capital Management, L.P. | 18,558 | 32,958 | +14,400 | 0.01 | 0.01 | +0.01 | buy |
| Aquatic Capital Management LLC | 17,163 | 31,915 | +14,752 | 0.00 | 0.01 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 30,756 | +30,756 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 88,487 | 28,453 | -60,034 | 0.00 | 0.00 | -0.00 | sell |
| FourThought Financial Partners, LLC | 0 | 27,533 | +27,533 | 0.00 | 0.03 | +0.03 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 27,370 | +27,370 | 0.00 | 0.05 | +0.05 | buy |
| Jump Financial, LLC | 197,466 | 27,357 | -170,109 | 0.03 | 0.00 | -0.03 | sell |
| Engineers Gate Manager LP | 69,022 | 27,181 | -41,841 | 0.01 | 0.00 | -0.01 | sell |
| WOLVERINE TRADING, LLC | 0 | 24,740 | +24,740 | 0.00 | 0.01 | +0.01 | buy |
| DEUTSCHE BANK AG\ | 19,960 | 22,914 | +2,954 | 0.00 | 0.00 | -0.00 | buy |
| NOMURA HOLDINGS INC | 23,807 | 20,617 | -3,190 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 6,505 | 20,029 | +13,524 | 0.00 | 0.00 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 0 | 19,119 | +19,119 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 346,978 | 19,079 | -327,899 | 0.00 | 0.00 | -0.00 | sell |
| MetLife Investment Management, LLC | 18,669 | 18,669 | 0 | 0.00 | 0.00 | -0.00 | hold |
| WELLS FARGO & COMPANY/MN | 15,821 | 18,541 | +2,720 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 18,006 | +18,006 | 0.00 | 0.00 | +0.00 | buy |
| Hunting Hill Global Capital, LLC | 22,668 | 17,882 | -4,786 | 0.17 | 0.07 | -0.09 | sell |
| WealthPlan Investment Management, LLC | 17,443 | 17,443 | 0 | 0.02 | 0.01 | -0.00 | hold |
| EntryPoint Capital, LLC | 0 | 17,248 | +17,248 | 0.00 | 0.07 | +0.07 | buy |
| ALPS ADVISORS INC | 18,823 | 16,874 | -1,949 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 29,432 | 16,203 | -13,229 | 0.02 | 0.01 | -0.01 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 15,078 | 16,076 | +998 | 0.00 | 0.00 | -0.00 | buy |
| Creative Planning | 0 | 15,584 | +15,584 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 14,476 | 15,560 | +1,084 | 0.00 | 0.00 | -0.00 | buy |
| PharVision Advisers, LLC | 0 | 15,035 | +15,035 | 0.00 | 0.09 | +0.09 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 16,497 | 14,154 | -2,343 | 0.00 | 0.00 | -0.00 | sell |
| Quadrature Capital Ltd | 20,883 | 14,025 | -6,858 | 0.00 | 0.00 | -0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 14,000 | 14,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ROYAL BANK OF CANADA | 0 | 12,570 | +12,570 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 168,245 | 12,501 | -155,744 | 0.00 | 0.00 | -0.00 | sell |
| NBC SECURITIES, INC. | 10,000 | 11,861 | +1,861 | 0.01 | 0.01 | -0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 11,101 | 10,316 | -785 | 0.00 | 0.00 | -0.00 | sell |
| Soleus Capital Management, L.P. | 25,000 | 10,000 | -15,000 | 0.02 | 0.01 | -0.02 | sell |
| Police & Firemen's Retirement System of New Jersey | 7,103 | 8,795 | +1,692 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 2,932 | 6,270 | +3,338 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 91,611 | 5,826 | -85,785 | 0.00 | 0.00 | -0.00 | sell |
| Point72 (DIFC) Ltd | 0 | 5,017 | +5,017 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 3,356 | 3,356 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ameritas Investment Partners, Inc. | 3,075 | 3,075 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Russell Investments Group, Ltd. | 0 | 2,709 | +2,709 | 0.00 | 0.00 | +0.00 | buy |
| Quarry LP | 1,893 | 2,640 | +747 | 0.01 | 0.01 | +0.00 | buy |
| MACQUARIE GROUP LTD | 0 | 2,393 | +2,393 | 0.00 | 0.00 | +0.00 | buy |
| State of Alaska, Department of Revenue | 0 | 2,011 | +2,011 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 1,886 | +1,886 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 1,880 | 1,882 | +2 | 0.00 | 0.00 | -0.00 | buy |
| Advisory Services Network, LLC | 0 | 1,302 | +1,302 | 0.00 | 0.00 | +0.00 | buy |