| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Deep Track Capital, LP | 1,933,928 | 4,564,207 | +2,630,279 | 2.53 | 4.46 | +1.92 | buy |
| T. Rowe Price Investment Management, Inc. | 14,169,199 | 16,175,533 | +2,006,334 | 0.31 | 0.32 | +0.02 | buy |
| BVF INC/IL | 0 | 1,913,385 | +1,913,385 | 0.00 | 2.35 | +2.35 | buy |
| CITADEL ADVISORS LLC | 2,165,916 | 3,480,062 | +1,314,146 | 0.07 | 0.10 | +0.03 | buy |
| FMR LLC | 22,689,491 | 23,613,585 | +924,094 | 0.05 | 0.05 | -0.00 | buy |
| Capital World Investors | 11,465,413 | 12,361,994 | +896,581 | 0.06 | 0.06 | -0.00 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 275,000 | 1,075,600 | +800,600 | 0.02 | 0.06 | +0.04 | buy |
| TWO SIGMA INVESTMENTS, LP | 921,439 | 1,685,853 | +764,414 | 0.07 | 0.11 | +0.04 | buy |
| TWO SIGMA ADVISERS, LP | 1,349,211 | 2,092,011 | +742,800 | 0.11 | 0.14 | +0.03 | buy |
| BANK OF MONTREAL /CAN/ | 312,146 | 782,835 | +470,689 | 0.01 | 0.01 | +0.01 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 65,792 | 500,451 | +434,659 | 0.01 | 0.06 | +0.05 | buy |
| BANK OF AMERICA CORP /DE/ | 422,861 | 767,432 | +344,571 | 0.00 | 0.00 | +0.00 | buy |
| Eversept Partners, LP | 214,952 | 517,021 | +302,069 | 0.78 | 1.77 | +0.99 | buy |
| Point72 Asset Management, L.P. | 0 | 287,204 | +287,204 | 0.00 | 0.02 | +0.02 | buy |
| GOLDMAN SACHS GROUP INC | 378,208 | 652,518 | +274,310 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 169,155 | 426,480 | +257,325 | 0.01 | 0.01 | +0.00 | buy |
| Hudson Bay Capital Management LP | 821,200 | 1,049,900 | +228,700 | 0.17 | 0.20 | +0.03 | buy |
| Schonfeld Strategic Advisors LLC | 371,381 | 560,359 | +188,978 | 0.08 | 0.11 | +0.03 | buy |
| Legal & General Group Plc | 168,080 | 338,462 | +170,382 | 0.00 | 0.00 | +0.00 | buy |
| Sovran Advisors, LLC | 171,812 | 328,904 | +157,092 | 0.80 | 1.21 | +0.41 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,687,248 | 2,842,954 | +155,706 | 0.01 | 0.01 | -0.00 | buy |
| Candriam S.C.A. | 849,824 | 993,704 | +143,880 | 0.17 | 0.19 | +0.02 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0 | 143,870 | +143,870 | 0.00 | 0.01 | +0.01 | buy |
| Squarepoint Ops LLC | 166,468 | 305,373 | +138,905 | 0.01 | 0.02 | +0.01 | buy |
| EDMOND DE ROTHSCHILD HOLDING S.A. | 0 | 124,200 | +124,200 | 0.00 | 0.07 | +0.07 | buy |
| AMERICAN CENTURY COMPANIES INC | 0 | 116,768 | +116,768 | 0.00 | 0.00 | +0.00 | buy |
| BNP Paribas Asset Management Holding S.A. | 1,080,341 | 1,196,392 | +116,051 | 0.09 | 0.10 | +0.00 | buy |
| Camber Capital Management LP | 625,000 | 725,000 | +100,000 | 0.85 | 1.36 | +0.51 | buy |
| Invesco Ltd. | 788,599 | 874,834 | +86,235 | 0.01 | 0.01 | -0.00 | buy |
| Walleye Capital LLC | 16,255 | 94,990 | +78,735 | 0.01 | 0.03 | +0.03 | buy |
| Exome Asset Management LLC | 61,367 | 135,616 | +74,249 | 1.61 | 3.66 | +2.05 | buy |
| PDT Partners, LLC | 28,994 | 96,056 | +67,062 | 0.09 | 0.21 | +0.12 | buy |
| SIMPLEX TRADING, LLC | 0 | 64,581 | +64,581 | 0.00 | 0.07 | +0.07 | buy |
| PINNACLE ASSOCIATES LTD | 547,642 | 608,517 | +60,875 | 0.26 | 0.27 | +0.01 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 316,943 | 377,204 | +60,261 | 0.04 | 0.04 | +0.00 | buy |
| Avidity Partners Management LP | 0 | 60,000 | +60,000 | 0.00 | 0.37 | +0.37 | buy |
| CAPITAL FUND MANAGEMENT S.A. | 0 | 58,014 | +58,014 | 0.00 | 0.02 | +0.02 | buy |
| LAZARD ASSET MANAGEMENT LLC | 6,557 | 60,758 | +54,201 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 254,521 | 308,293 | +53,772 | 0.01 | 0.01 | +0.00 | buy |
| GROUPAMA ASSET MANAGMENT | 517,191 | 569,211 | +52,020 | 0.38 | 0.36 | -0.01 | buy |
| TD ASSET MANAGEMENT INC | 1,049,990 | 1,100,466 | +50,476 | 0.03 | 0.03 | -0.00 | buy |
| SECTOR GAMMA AS | 235,842 | 285,842 | +50,000 | 2.83 | 2.76 | -0.07 | buy |
| ALLIANCEBERNSTEIN L.P. | 52,136 | 100,749 | +48,613 | 0.00 | 0.00 | +0.00 | buy |
| READYSTATE ASSET MANAGEMENT LP | 0 | 46,394 | +46,394 | 0.00 | 0.07 | +0.07 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 26,064 | 71,811 | +45,747 | 0.00 | 0.00 | +0.00 | buy |
| Aberdeen Group plc | 401,501 | 446,197 | +44,696 | 0.03 | 0.03 | -0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 105,619 | 148,690 | +43,071 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 39,737 | 81,321 | +41,584 | 0.03 | 0.04 | +0.01 | buy |
| Point72 (DIFC) Ltd | 0 | 41,347 | +41,347 | 0.00 | 0.12 | +0.12 | buy |
| Raiffeisen Bank International AG | 1,754 | 41,754 | +40,000 | 0.00 | 0.02 | +0.02 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 619,641 | 659,435 | +39,794 | 0.01 | 0.01 | +0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 60,580 | 90,779 | +30,199 | 0.05 | 0.07 | +0.01 | buy |
| AXQ CAPITAL, LP | 0 | 30,104 | +30,104 | 0.00 | 0.36 | +0.36 | buy |
| Alpine Global Management, LLC | 0 | 28,097 | +28,097 | 0.00 | 0.22 | +0.22 | buy |
| ExodusPoint Capital Management, LP | 0 | 26,261 | +26,261 | 0.00 | 0.01 | +0.01 | buy |
| HRT FINANCIAL LP | 0 | 25,824 | +25,824 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 15,595 | 37,772 | +22,177 | 0.05 | 0.11 | +0.07 | buy |
| Daiwa Securities Group Inc. | 541 | 22,141 | +21,600 | 0.00 | 0.00 | +0.00 | buy |
| TWINBEECH CAPITAL LP | 0 | 15,938 | +15,938 | 0.00 | 0.01 | +0.01 | buy |
| Point72 Hong Kong Ltd | 0 | 12,862 | +12,862 | 0.00 | 0.03 | +0.03 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 12,207 | +12,207 | 0.00 | 0.00 | +0.00 | buy |
| DCF Advisers, LLC | 82,882 | 95,000 | +12,118 | 1.46 | 1.54 | +0.08 | buy |
| SIH Partners, LLLP | 0 | 11,999 | +11,999 | 0.00 | 0.03 | +0.03 | buy |
| FORA Capital, LLC | 0 | 11,570 | +11,570 | 0.00 | 0.04 | +0.04 | buy |
| Capula Management Ltd | 0 | 10,382 | +10,382 | 0.00 | 0.00 | +0.00 | buy |
| Virtus Investment Advisers, LLC | 0 | 9,701 | +9,701 | 0.00 | 0.08 | +0.08 | buy |
| Jain Global LLC | 0 | 8,595 | +8,595 | 0.00 | 0.01 | +0.01 | buy |
| Quantinno Capital Management LP | 0 | 8,515 | +8,515 | 0.00 | 0.00 | +0.00 | buy |
| Bayesian Capital Management, LP | 0 | 8,500 | +8,500 | 0.00 | 0.04 | +0.04 | buy |
| Pathstone Holdings, LLC | 26,058 | 34,372 | +8,314 | 0.00 | 0.00 | +0.00 | buy |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 0 | 8,059 | +8,059 | 0.00 | 0.03 | +0.03 | buy |
| FIDUCIARY TRUST CO | 0 | 7,738 | +7,738 | 0.00 | 0.00 | +0.00 | buy |
| Semanteon Capital Management, LP | 0 | 7,543 | +7,543 | 0.00 | 0.12 | +0.12 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 101,231 | 108,316 | +7,085 | 0.01 | 0.01 | -0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 0 | 6,263 | +6,263 | 0.00 | 0.00 | +0.00 | buy |
| GUGGENHEIM CAPITAL LLC | 35,373 | 41,414 | +6,041 | 0.01 | 0.01 | +0.00 | buy |
| Neuberger Berman Group LLC | 96,631 | 102,473 | +5,842 | 0.00 | 0.00 | -0.00 | buy |
| Mariner, LLC | 27,661 | 33,483 | +5,822 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 415,919 | 421,511 | +5,592 | 0.00 | 0.00 | -0.00 | buy |
| Sonora Investment Management Group, LLC | 148,776 | 154,147 | +5,371 | 0.40 | 0.37 | -0.03 | buy |
| Bleakley Financial Group, LLC | 16,942 | 22,284 | +5,342 | 0.02 | 0.02 | +0.00 | buy |
| Moisand Fitzgerald Tamayo, LLC | 0 | 5,000 | +5,000 | 0.00 | 0.02 | +0.02 | buy |
| CANADA LIFE ASSURANCE Co | 39,214 | 43,853 | +4,639 | 0.00 | 0.00 | -0.00 | buy |
| Tidal Investments LLC | 17,407 | 21,833 | +4,426 | 0.00 | 0.01 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 9,338 | 13,735 | +4,397 | 0.00 | 0.00 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 125,389 | 129,273 | +3,884 | 0.02 | 0.02 | -0.00 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 178 | 3,244 | +3,066 | 0.00 | 0.00 | +0.00 | buy |
| OPPENHEIMER ASSET MANAGEMENT INC. | 90,000 | 93,000 | +3,000 | 0.00 | 0.00 | +0.00 | buy |
| Treasurer of the State of North Carolina | 68,803 | 71,593 | +2,790 | 0.01 | 0.01 | -0.00 | buy |
| Significant Wealth Partners LLC | 10,905 | 13,605 | +2,700 | 0.20 | 0.21 | +0.01 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 2,345 | +2,345 | 0.00 | 0.00 | +0.00 | buy |
| SECTORAL ASSET MANAGEMENT INC | 7,200 | 9,440 | +2,240 | 0.17 | 0.22 | +0.05 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 2,082 | +2,082 | 0.00 | 0.02 | +0.02 | buy |
| Ancora Advisors LLC | 0 | 2,000 | +2,000 | 0.00 | 0.00 | +0.00 | buy |
| GRANDFIELD & DODD, LLC | 35,887 | 37,761 | +1,874 | 0.08 | 0.07 | -0.01 | buy |
| Ensign Peak Advisors, Inc | 53,320 | 55,100 | +1,780 | 0.00 | 0.00 | -0.00 | buy |
| Focus Partners Wealth | 8,055 | 9,832 | +1,777 | 0.00 | 0.00 | +0.00 | buy |
| Teza Capital Management LLC | 8,525 | 10,244 | +1,719 | 0.05 | 0.14 | +0.10 | buy |
| Man Group plc | 8,315 | 10,033 | +1,718 | 0.00 | 0.00 | +0.00 | buy |
| Nicollet Investment Management, Inc. | 19,786 | 21,451 | +1,665 | 0.24 | 0.23 | -0.01 | buy |