| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Sonora Investment Management Group, LLC | 0 | 5,499,000 | +5,499,000 | 0.00 | 0.42 | +0.42 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | 5,362,000 | +5,362,000 | 0.00 | 0.01 | +0.01 | buy |
| Capital World Investors | 7,828,372 | 11,465,413 | +3,637,041 | 0.05 | 0.06 | +0.01 | buy |
| CITADEL ADVISORS LLC | 401,151 | 2,165,916 | +1,764,765 | 0.02 | 0.07 | +0.05 | buy |
| UBS Group AG | 167,880 | 1,917,608 | +1,749,728 | 0.00 | 0.02 | +0.01 | buy |
| VANGUARD GROUP INC | 15,055,758 | 16,472,539 | +1,416,781 | 0.01 | 0.01 | -0.00 | buy |
| BlackRock, Inc. | 10,813,023 | 11,665,548 | +852,525 | 0.01 | 0.01 | -0.00 | buy |
| Camber Capital Management LP | 0 | 625,000 | +625,000 | 0.00 | 0.85 | +0.85 | buy |
| Vestal Point Capital, LP | 0 | 595,000 | +595,000 | 0.00 | 1.23 | +1.23 | buy |
| STATE STREET CORP | 4,850,137 | 5,426,413 | +576,276 | 0.01 | 0.01 | -0.00 | buy |
| ORBIMED ADVISORS LLC | 2,324,447 | 2,817,347 | +492,900 | 1.70 | 2.05 | +0.34 | buy |
| MILLENNIUM MANAGEMENT LLC | 430,723 | 774,215 | +343,492 | 0.01 | 0.02 | +0.01 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 285,697 | 619,641 | +333,944 | 0.00 | 0.01 | +0.00 | buy |
| BNP Paribas Asset Management Holding S.A. | 779,721 | 1,080,341 | +300,620 | 0.08 | 0.09 | +0.02 | buy |
| GREAT POINT PARTNERS LLC | 255,000 | 505,007 | +250,007 | 3.08 | 8.32 | +5.24 | buy |
| Aquatic Capital Management LLC | 0 | 230,016 | +230,016 | 0.00 | 0.22 | +0.22 | buy |
| FMR LLC | 22,479,529 | 22,689,491 | +209,962 | 0.05 | 0.05 | -0.01 | buy |
| Verition Fund Management LLC | 0 | 200,184 | +200,184 | 0.00 | 0.04 | +0.04 | buy |
| GW&K Investment Management, LLC | 0 | 187,220 | +187,220 | 0.00 | 0.06 | +0.06 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 45,574 | 213,015 | +167,441 | 0.05 | 0.12 | +0.07 | buy |
| GOLDMAN SACHS GROUP INC | 235,710 | 378,208 | +142,498 | 0.00 | 0.00 | +0.00 | buy |
| BAKER BROS. ADVISORS LP | 223,470 | 357,915 | +134,445 | 0.09 | 0.13 | +0.04 | buy |
| Assenagon Asset Management S.A. | 13,298 | 141,917 | +128,619 | 0.00 | 0.01 | +0.01 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 17,741 | 125,389 | +107,648 | 0.00 | 0.02 | +0.02 | buy |
| Woodline Partners LP | 0 | 107,610 | +107,610 | 0.00 | 0.03 | +0.03 | buy |
| GROUPAMA ASSET MANAGMENT | 416,060 | 517,191 | +101,131 | 0.35 | 0.38 | +0.03 | buy |
| C WorldWide Group Holding A/S | 300,000 | 400,000 | +100,000 | 0.12 | 0.17 | +0.05 | buy |
| CITIGROUP INC | 70,295 | 169,155 | +98,860 | 0.00 | 0.01 | +0.00 | buy |
| BANK OF MONTREAL /CAN/ | 213,883 | 312,146 | +98,263 | 0.00 | 0.01 | +0.00 | buy |
| Aberdeen Group plc | 303,274 | 401,501 | +98,227 | 0.02 | 0.03 | +0.00 | buy |
| NORTHERN TRUST CORP | 742,904 | 840,271 | +97,367 | 0.00 | 0.00 | -0.00 | buy |
| PINNACLE ASSOCIATES LTD | 458,979 | 547,642 | +88,663 | 0.39 | 0.26 | -0.14 | buy |
| HSBC HOLDINGS PLC | 0 | 83,055 | +83,055 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 175,328 | 254,521 | +79,193 | 0.01 | 0.01 | +0.00 | buy |
| NOMURA HOLDINGS INC | 0 | 78,282 | +78,282 | 0.00 | 0.01 | +0.01 | buy |
| Twin Tree Management, LP | 12,428 | 88,900 | +76,472 | 0.01 | 0.08 | +0.06 | buy |
| Exome Asset Management LLC | 0 | 61,367 | +61,367 | 0.00 | 1.61 | +1.61 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 162,076 | 223,278 | +61,202 | 0.14 | 0.17 | +0.03 | buy |
| Hudson Bay Capital Management LP | 766,900 | 821,200 | +54,300 | 0.21 | 0.17 | -0.04 | buy |
| Qsemble Capital Management, LP | 0 | 46,573 | +46,573 | 0.00 | 0.22 | +0.22 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 56,222 | 100,659 | +44,437 | 0.00 | 0.00 | +0.00 | buy |
| AXA S.A. | 561,243 | 605,345 | +44,102 | 0.07 | 0.06 | -0.00 | buy |
| DCF Advisers, LLC | 39,500 | 82,882 | +43,382 | 0.81 | 1.46 | +0.65 | buy |
| Jump Financial, LLC | 0 | 39,737 | +39,737 | 0.00 | 0.03 | +0.03 | buy |
| Squarepoint Ops LLC | 127,341 | 166,468 | +39,127 | 0.02 | 0.01 | -0.00 | buy |
| Rafferty Asset Management, LLC | 198,759 | 237,337 | +38,578 | 0.03 | 0.03 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,443,020 | 1,481,440 | +38,420 | 0.01 | 0.01 | -0.00 | buy |
| CHOREO, LLC | 0 | 37,000 | +37,000 | 0.00 | 0.00 | +0.00 | buy |
| Neuberger Berman Group LLC | 64,874 | 96,631 | +31,757 | 0.00 | 0.00 | +0.00 | buy |
| STIFEL FINANCIAL CORP | 182,505 | 211,493 | +28,988 | 0.01 | 0.01 | +0.00 | buy |
| BlueCrest Capital Management Ltd | 0 | 26,200 | +26,200 | 0.00 | 0.05 | +0.05 | buy |
| SECTOR GAMMA AS | 210,842 | 235,842 | +25,000 | 2.56 | 2.83 | +0.27 | buy |
| Proficio Capital Partners LLC | 0 | 23,703 | +23,703 | 0.00 | 0.00 | +0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 36,957 | 60,580 | +23,623 | 0.04 | 0.05 | +0.02 | buy |
| Swiss National Bank | 256,600 | 279,200 | +22,600 | 0.01 | 0.01 | -0.00 | buy |
| MORGAN STANLEY | 1,310,451 | 1,329,929 | +19,478 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,668,358 | 2,687,248 | +18,890 | 0.01 | 0.01 | -0.00 | buy |
| Creative Planning | 28,382 | 46,803 | +18,421 | 0.00 | 0.00 | +0.00 | buy |
| Rhenman & Partners Asset Management AB | 195,000 | 212,500 | +17,500 | 0.63 | 0.76 | +0.13 | buy |
| DEUTSCHE BANK AG\ | 74,874 | 91,901 | +17,027 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 1,332,411 | 1,349,211 | +16,800 | 0.13 | 0.11 | -0.02 | buy |
| NATIXIS | 0 | 16,626 | +16,626 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 7,419 | 23,927 | +16,508 | 0.00 | 0.00 | +0.00 | buy |
| Privium Fund Management B.V. | 250,744 | 266,794 | +16,050 | 2.50 | 2.11 | -0.39 | buy |
| Campbell & CO Investment Adviser LLC | 0 | 15,681 | +15,681 | 0.00 | 0.04 | +0.04 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 15,595 | +15,595 | 0.00 | 0.05 | +0.05 | buy |
| PDT Partners, LLC | 13,400 | 28,994 | +15,594 | 0.05 | 0.09 | +0.04 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 86,166 | 101,231 | +15,065 | 0.01 | 0.01 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 190,514 | 205,514 | +15,000 | 0.01 | 0.01 | -0.00 | buy |
| INCEPTIONR LLC | 0 | 14,390 | +14,390 | 0.00 | 0.11 | +0.11 | buy |
| Essential Planning, LLC. | 0 | 11,440 | +11,440 | 0.00 | 0.00 | +0.00 | buy |
| State of New Jersey Common Pension Fund D | 51,775 | 63,206 | +11,431 | 0.01 | 0.01 | +0.00 | buy |
| Significant Wealth Partners LLC | 0 | 10,905 | +10,905 | 0.00 | 0.20 | +0.20 | buy |
| Legal & General Group Plc | 157,287 | 168,080 | +10,793 | 0.00 | 0.00 | -0.00 | buy |
| Bridgefront Capital, LLC | 11,196 | 21,802 | +10,606 | 0.17 | 0.26 | +0.08 | buy |
| SYON CAPITAL LLC | 0 | 10,119 | +10,119 | 0.00 | 0.03 | +0.03 | buy |
| Tower Research Capital LLC (TRC) | 4,301 | 14,157 | +9,856 | 0.00 | 0.01 | +0.01 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 56,699 | 65,792 | +9,093 | 0.01 | 0.01 | -0.00 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 11,200 | 19,900 | +8,700 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 16,805 | 25,362 | +8,557 | 0.05 | 0.07 | +0.03 | buy |
| Schonfeld Strategic Advisors LLC | 362,888 | 371,381 | +8,493 | 0.12 | 0.08 | -0.04 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 126,180 | 133,902 | +7,722 | 0.01 | 0.01 | -0.00 | buy |
| PRAXIS INVESTMENT MANAGEMENT INC | 0 | 6,770 | +6,770 | 0.00 | 0.02 | +0.02 | buy |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 0 | 6,617 | +6,617 | 0.00 | 0.00 | +0.00 | buy |
| EntryPoint Capital, LLC | 0 | 6,382 | +6,382 | 0.00 | 0.09 | +0.09 | buy |
| Walleye Trading LLC | 3,613 | 9,920 | +6,307 | 0.00 | 0.01 | +0.00 | buy |
| AIGEN INVESTMENT MANAGEMENT, LP | 11,612 | 17,723 | +6,111 | 0.09 | 0.11 | +0.02 | buy |
| Quarry LP | 0 | 6,000 | +6,000 | 0.00 | 0.04 | +0.04 | buy |
| PROFUND ADVISORS LLC | 37,596 | 43,559 | +5,963 | 0.06 | 0.06 | -0.00 | buy |
| STEVENS CAPITAL MANAGEMENT LP | 0 | 5,860 | +5,860 | 0.00 | 0.08 | +0.08 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 30,922 | 36,322 | +5,400 | 0.00 | 0.00 | -0.00 | buy |
| China Universal Asset Management Co., Ltd. | 28,121 | 33,480 | +5,359 | 0.12 | 0.11 | -0.01 | buy |
| Bank of New York Mellon Corp | 610,893 | 616,071 | +5,178 | 0.00 | 0.00 | -0.00 | buy |
| Harbor Advisors LLC | 5,500 | 10,500 | +5,000 | 0.04 | 0.06 | +0.02 | buy |
| JANUS HENDERSON GROUP PLC | 58,977 | 63,877 | +4,900 | 0.00 | 0.00 | -0.00 | buy |
| Mariner, LLC | 23,127 | 27,661 | +4,534 | 0.00 | 0.00 | -0.00 | buy |
| TORNO CAPITAL, LLC | 5,000 | 9,500 | +4,500 | 0.26 | 0.07 | -0.19 | buy |
| E Fund Management Co., Ltd. | 12,752 | 16,868 | +4,116 | 0.03 | 0.03 | +0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 8,404 | 12,271 | +3,867 | 0.01 | 0.01 | +0.00 | buy |
| Arizona State Retirement System | 37,827 | 41,147 | +3,320 | 0.01 | 0.01 | -0.00 | buy |