| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 12,188,586 | 14,407,330 | +2,218,744 | 0.08 | 0.08 | +0.00 | buy |
| Invesco Ltd. | 1,181,374 | 1,814,666 | +633,292 | 0.08 | 0.11 | +0.03 | buy |
| T. Rowe Price Investment Management, Inc. | 4,754,991 | 5,357,326 | +602,335 | 0.86 | 0.90 | +0.04 | buy |
| FIL Ltd | 63,344 | 656,502 | +593,158 | 0.02 | 0.18 | +0.16 | buy |
| FIRST TRUST ADVISORS LP | 405,513 | 977,308 | +571,795 | 0.12 | 0.28 | +0.15 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,163,530 | 1,508,346 | +344,816 | 0.04 | 0.05 | +0.01 | buy |
| Aberdeen Group plc | 129,543 | 437,075 | +307,532 | 0.08 | 0.25 | +0.16 | buy |
| GOLDMAN SACHS GROUP INC | 790,845 | 1,095,823 | +304,978 | 0.05 | 0.06 | +0.01 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 60,895 | 355,808 | +294,913 | 0.04 | 0.19 | +0.16 | buy |
| ORBIMED ADVISORS LLC | 556,800 | 827,600 | +270,800 | 3.07 | 4.29 | +1.22 | buy |
| DEUTSCHE BANK AG\ | 936,482 | 1,189,890 | +253,408 | 0.16 | 0.16 | +0.00 | buy |
| PRIMECAP MANAGEMENT CO/CA/ | 16,012,566 | 16,264,481 | +251,915 | 3.47 | 3.33 | -0.14 | buy |
| VAN ECK ASSOCIATES CORP | 1,189,546 | 1,421,196 | +231,650 | 0.67 | 0.67 | -0.00 | buy |
| JANE STREET GROUP, LLC | 46,854 | 204,688 | +157,834 | 0.02 | 0.06 | +0.05 | buy |
| BARCLAYS PLC | 395,676 | 532,260 | +136,584 | 0.07 | 0.07 | +0.01 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 446,602 | 580,065 | +133,463 | 0.04 | 0.05 | +0.01 | buy |
| BANK OF NOVA SCOTIA | 30,094 | 160,263 | +130,169 | 0.02 | 0.08 | +0.06 | buy |
| TD ASSET MANAGEMENT INC | 281,028 | 389,984 | +108,956 | 0.09 | 0.10 | +0.01 | buy |
| Amundi | 1,093,524 | 1,201,706 | +108,182 | 0.14 | 0.14 | -0.00 | buy |
| Epoch Investment Partners, Inc. | 186,046 | 277,224 | +91,178 | 0.30 | 0.33 | +0.02 | buy |
| AMERICAN CENTURY COMPANIES INC | 898,928 | 988,676 | +89,748 | 0.18 | 0.18 | -0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 230,411 | 317,302 | +86,891 | 0.17 | 0.23 | +0.06 | buy |
| BANK OF MONTREAL /CAN/ | 206,843 | 292,400 | +85,557 | 0.02 | 0.02 | +0.01 | buy |
| MORGAN STANLEY | 1,493,113 | 1,577,777 | +84,664 | 0.04 | 0.04 | -0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 116,991 | 201,275 | +84,284 | 0.05 | 0.10 | +0.04 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 281,163 | 363,209 | +82,046 | 0.06 | 0.07 | +0.01 | buy |
| Woodline Partners LP | 0 | 80,600 | +80,600 | 0.00 | 0.23 | +0.23 | buy |
| STATE STREET CORP | 6,865,654 | 6,945,665 | +80,011 | 0.10 | 0.09 | -0.01 | buy |
| BANK OF AMERICA CORP /DE/ | 354,093 | 426,574 | +72,481 | 0.01 | 0.01 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 3,236,887 | 3,309,317 | +72,430 | 0.10 | 0.09 | -0.01 | buy |
| Man Group plc | 0 | 70,008 | +70,008 | 0.09 | 0.05 | -0.03 | buy |
| ROYAL BANK OF CANADA | 306,554 | 374,014 | +67,460 | 0.02 | 0.02 | +0.00 | buy |
| Squarepoint Ops LLC | 32,788 | 90,302 | +57,514 | 0.04 | 0.10 | +0.05 | buy |
| HSBC HOLDINGS PLC | 272,634 | 325,608 | +52,974 | 0.08 | 0.08 | -0.00 | buy |
| Hudson Bay Capital Management LP | 82,500 | 135,000 | +52,500 | 0.20 | 0.31 | +0.10 | buy |
| Carmignac Gestion | 309,100 | 361,395 | +52,295 | 1.46 | 1.57 | +0.11 | buy |
| Tri Locum Partners LP | 0 | 45,814 | +45,814 | 0.00 | 5.82 | +5.82 | buy |
| NATIXIS | 21,535 | 67,073 | +45,538 | 0.04 | 0.13 | +0.09 | buy |
| Pictet Asset Management Holding SA | 1,212,482 | 1,257,959 | +45,477 | 0.38 | 0.36 | -0.03 | buy |
| Zimmer Partners, LP | 72,900 | 116,700 | +43,800 | 0.49 | 1.11 | +0.61 | buy |
| DIMENSIONAL FUND ADVISORS LP | 1,381,215 | 1,424,659 | +43,444 | 0.12 | 0.11 | -0.01 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 54,683 | 92,631 | +37,948 | 0.02 | 0.03 | +0.01 | buy |
| TWO SIGMA INVESTMENTS, LP | 19,514 | 54,025 | +34,511 | 0.01 | 0.03 | +0.02 | buy |
| Capital World Investors | 0 | 34,200 | +34,200 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 163,521 | 197,602 | +34,081 | 0.09 | 0.09 | -0.00 | buy |
| Korea Investment CORP | 144,136 | 175,795 | +31,659 | 0.11 | 0.12 | +0.01 | buy |
| MOORE CAPITAL MANAGEMENT, LP | 60,000 | 90,000 | +30,000 | 0.42 | 0.56 | +0.14 | buy |
| State of Tennessee, Department of Treasury | 37,046 | 63,396 | +26,350 | 0.04 | 0.06 | +0.03 | buy |
| JPMORGAN CHASE & CO | 4,985,628 | 5,011,319 | +25,691 | 0.15 | 0.13 | -0.02 | buy |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 0 | 25,000 | +25,000 | 0.00 | 0.02 | +0.02 | buy |
| Sivik Global Healthcare LLC | 0 | 25,000 | +25,000 | 0.00 | 2.70 | +2.70 | buy |
| STONERIDGE INVESTMENT PARTNERS LLC | 0 | 24,322 | +24,322 | 0.00 | 2.65 | +2.65 | buy |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | 0 | 20,830 | +20,830 | 0.00 | 0.29 | +0.29 | buy |
| Investment Management Corp of Ontario | 0 | 20,557 | +20,557 | 0.00 | 0.13 | +0.13 | buy |
| SPHERA FUNDS MANAGEMENT LTD. | 25,846 | 46,346 | +20,500 | 1.59 | 2.23 | +0.63 | buy |
| AVIVA PLC | 49,189 | 66,959 | +17,770 | 0.05 | 0.06 | +0.01 | buy |
| Tower Research Capital LLC (TRC) | 10,087 | 27,389 | +17,302 | 0.08 | 0.09 | +0.01 | buy |
| WELLS FARGO & COMPANY/MN | 214,673 | 231,451 | +16,778 | 0.02 | 0.02 | -0.00 | buy |
| CIBC WORLD MARKETS CORP | 24,653 | 39,452 | +14,799 | 0.06 | 0.06 | -0.01 | buy |
| China Universal Asset Management Co., Ltd. | 4,393 | 19,027 | +14,634 | 0.33 | 0.96 | +0.63 | buy |
| Prime Capital Investment Advisors, LLC | 0 | 14,199 | +14,199 | 0.00 | 0.06 | +0.06 | buy |
| Varma Mutual Pension Insurance Co | 0 | 14,100 | +14,100 | 0.00 | 0.04 | +0.04 | buy |
| MACKENZIE FINANCIAL CORP | 46,830 | 60,626 | +13,796 | 0.02 | 0.02 | +0.00 | buy |
| Rafferty Asset Management, LLC | 82,547 | 95,882 | +13,335 | 0.12 | 0.10 | -0.02 | buy |
| FRED ALGER MANAGEMENT, LLC | 0 | 13,235 | +13,235 | 0.00 | 0.02 | +0.02 | buy |
| Kintegral Advisory, LLC | 0 | 12,761 | +12,761 | 0.00 | 0.37 | +0.37 | buy |
| Pacer Advisors, Inc. | 16,586 | 28,929 | +12,343 | 0.02 | 0.02 | +0.00 | buy |
| Arlington Partners LLC | 0 | 11,656 | +11,656 | 0.00 | 0.87 | +0.87 | buy |
| Bayesian Capital Management, LP | 0 | 11,600 | +11,600 | 0.00 | 0.32 | +0.32 | buy |
| Diversified Trust Co | 0 | 11,272 | +11,272 | 0.00 | 0.10 | +0.10 | buy |
| APG Asset Management N.V. | 112,198 | 123,236 | +11,038 | 0.06 | 0.06 | -0.00 | buy |
| Beck Bode, LLC | 0 | 10,677 | +10,677 | 0.00 | 0.62 | +0.62 | buy |
| AXA S.A. | 441,249 | 450,743 | +9,494 | 0.40 | 0.38 | -0.02 | buy |
| WEDGE CAPITAL MANAGEMENT L L P/NC | 118,204 | 127,488 | +9,284 | 0.60 | 0.59 | -0.01 | buy |
| OSTRUM ASSET MANAGEMENT | 11,198 | 20,310 | +9,112 | 0.27 | 0.46 | +0.19 | buy |
| Vontobel Holding Ltd. | 14,431 | 22,930 | +8,499 | 0.03 | 0.05 | +0.02 | buy |
| Corient Private Wealth LLC | 22,759 | 31,212 | +8,453 | 0.01 | 0.01 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 2,344 | 10,291 | +7,947 | 0.01 | 0.03 | +0.03 | buy |
| Mitsubishi UFJ Asset Management Co., Ltd. | 141,745 | 149,428 | +7,683 | 0.07 | 0.07 | -0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 128,196 | 135,176 | +6,980 | 0.02 | 0.02 | +0.00 | buy |
| PineBridge Investments, L.P. | 13,266 | 20,104 | +6,838 | 0.04 | 0.05 | +0.01 | buy |
| National Pension Service | 295,942 | 302,317 | +6,375 | 0.12 | 0.11 | -0.01 | buy |
| STEVENS CAPITAL MANAGEMENT LP | 0 | 6,304 | +6,304 | 0.00 | 0.41 | +0.41 | buy |
| Ethic Inc. | 7,569 | 13,859 | +6,290 | 0.07 | 0.11 | +0.04 | buy |
| Alaska Permanent Fund Corp | 0 | 6,103 | +6,103 | 0.00 | 0.03 | +0.03 | buy |
| Summit Global Investments | 0 | 6,088 | +6,088 | 0.00 | 0.10 | +0.10 | buy |
| Farther Finance Advisors, LLC | 1,178 | 7,196 | +6,018 | 0.05 | 0.13 | +0.09 | buy |
| Aquatic Capital Management LLC | 880 | 6,800 | +5,920 | 0.01 | 0.04 | +0.04 | buy |
| Schonfeld Strategic Advisors LLC | 1,835 | 7,520 | +5,685 | 0.00 | 0.02 | +0.01 | buy |
| KESTRA PRIVATE WEALTH SERVICES, LLC | 0 | 5,262 | +5,262 | 0.00 | 0.03 | +0.03 | buy |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 0 | 5,234 | +5,234 | 0.00 | 0.05 | +0.05 | buy |
| Eaton Financial Holdings Company, LLC | 0 | 5,062 | +5,062 | 0.00 | 0.32 | +0.32 | buy |
| ICICI Prudential Asset Management Co Ltd | 31,296 | 35,989 | +4,693 | 1.05 | 1.08 | +0.03 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 378,509 | 383,102 | +4,593 | 0.08 | 0.07 | -0.01 | buy |
| PDT Partners, LLC | 1,600 | 6,125 | +4,525 | 0.05 | 0.18 | +0.12 | buy |
| Atria Investments, Inc | 0 | 4,374 | +4,374 | 0.00 | 0.02 | +0.02 | buy |
| Cresset Asset Management, LLC | 6,068 | 10,366 | +4,298 | 0.01 | 0.02 | +0.01 | buy |
| Channing Capital Management, LLC | 30,026 | 34,103 | +4,077 | 0.25 | 0.26 | +0.01 | buy |
| Apollon Wealth Management, LLC | 1,004 | 4,994 | +3,990 | 0.01 | 0.04 | +0.03 | buy |
| DOHJ, LLC | 0 | 3,675 | +3,675 | 0.00 | 0.28 | +0.28 | buy |