| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 36,179,122 | 36,179,665 | +543 | 25.85 | 25.86 | +0.01 | buy |
| VANGUARD GROUP INC | 22,519,381 | 22,715,821 | +196,440 | 0.03 | 0.03 | -0.01 | buy |
| DODGE & COX | 16,090,421 | 15,416,043 | -674,378 | 0.64 | 0.51 | -0.13 | sell |
| STATE STREET CORP | 10,120,170 | 9,899,546 | -220,624 | 0.03 | 0.03 | -0.01 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 5,553,937 | 5,676,437 | +122,500 | 0.54 | 0.51 | -0.03 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 4,273,448 | 4,439,896 | +166,448 | 0.03 | 0.02 | -0.00 | buy |
| MORGAN STANLEY | 3,355,698 | 2,922,318 | -433,380 | 0.02 | 0.01 | -0.01 | sell |
| Amundi | 3,052,505 | 2,821,461 | -231,044 | 0.09 | 0.06 | -0.02 | sell |
| Invesco Ltd. | 2,736,322 | 2,818,295 | +81,973 | 0.04 | 0.03 | -0.01 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 3,016,239 | 2,781,746 | -234,493 | 0.73 | 0.55 | -0.18 | sell |
| LSV ASSET MANAGEMENT | 2,691,827 | 2,754,777 | +62,950 | 0.37 | 0.32 | -0.04 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 2,336,782 | 2,514,634 | +177,852 | 0.74 | 0.64 | -0.10 | buy |
| ARMISTICE CAPITAL, LLC | 236,000 | 2,187,181 | +1,951,181 | 0.39 | 3.32 | +2.92 | buy |
| Bellevue Group AG | 2,156,719 | 2,153,388 | -3,331 | 2.07 | 1.87 | -0.20 | sell |
| Man Group plc | 2,376,434 | 2,098,656 | -277,778 | 0.43 | 0.32 | -0.11 | sell |
| NORGES BANK | 1,962,937 | 2,052,072 | +89,135 | 0.02 | 0.02 | -0.00 | buy |
| NORTHERN TRUST CORP | 1,981,495 | 1,850,967 | -130,528 | 0.02 | 0.02 | -0.00 | sell |
| Pictet Asset Management Holding SA | 2,336,246 | 1,709,973 | -626,273 | 0.16 | 0.11 | -0.06 | sell |
| Legal & General Group Plc | 1,694,794 | 1,685,891 | -8,903 | 0.03 | 0.03 | -0.01 | sell |
| FMR LLC | 1,330,119 | 1,623,902 | +293,783 | 0.01 | 0.01 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 1,182,713 | 1,560,717 | +378,004 | 0.14 | 0.15 | +0.01 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 1,570,296 | 1,540,456 | -29,840 | 0.37 | 0.30 | -0.07 | sell |
| KBC Group NV | 955,749 | 1,538,887 | +583,138 | 0.21 | 0.28 | +0.07 | buy |
| Candriam S.C.A. | 1,040,289 | 1,473,797 | +433,508 | 0.45 | 0.54 | +0.09 | buy |
| D. E. Shaw & Co., Inc. | 1,501,024 | 1,385,593 | -115,431 | 0.14 | 0.10 | -0.03 | sell |
| TWO SIGMA ADVISERS, LP | 1,769,100 | 1,342,400 | -426,700 | 0.26 | 0.18 | -0.08 | sell |
| Sofinnova Investments, Inc. | 296,569 | 1,327,178 | +1,030,609 | 1.04 | 4.46 | +3.42 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,326,814 | 1,324,959 | -1,855 | 0.02 | 0.02 | -0.00 | sell |
| Qube Research & Technologies Ltd | 958,174 | 1,222,629 | +264,455 | 0.14 | 0.13 | -0.01 | buy |
| Bank of New York Mellon Corp | 1,266,064 | 1,212,298 | -53,766 | 0.02 | 0.01 | -0.00 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,217,762 | 1,206,579 | -11,183 | 0.03 | 0.02 | -0.01 | sell |
| Connor, Clark & Lunn Investment Management Ltd. | 916,363 | 1,187,411 | +271,048 | 0.27 | 0.29 | +0.02 | buy |
| HSBC HOLDINGS PLC | 1,018,706 | 1,175,652 | +156,946 | 0.06 | 0.05 | -0.01 | buy |
| APG Asset Management N.V. | 1,068,202 | 1,163,721 | +95,519 | 0.12 | 0.11 | -0.01 | buy |
| Robeco Institutional Asset Management B.V. | 1,065,777 | 1,151,718 | +85,941 | 0.16 | 0.14 | -0.02 | buy |
| Woodline Partners LP | 1,132,817 | 1,133,492 | +675 | 0.78 | 0.60 | -0.18 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 1,169,995 | 1,109,249 | -60,746 | 0.06 | 0.04 | -0.01 | sell |
| JUPITER ASSET MANAGEMENT LTD | 1,093,478 | 1,081,843 | -11,635 | 0.68 | 0.59 | -0.09 | sell |
| TWO SIGMA INVESTMENTS, LP | 1,911,787 | 1,054,488 | -857,299 | 0.29 | 0.15 | -0.14 | sell |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 1,260,622 | 1,047,868 | -212,754 | 0.31 | 0.22 | -0.09 | sell |
| DEUTSCHE BANK AG\ | 1,108,832 | 1,044,503 | -64,329 | 0.04 | 0.03 | -0.01 | sell |
| Russell Investments Group, Ltd. | 963,090 | 1,033,557 | +70,467 | 0.11 | 0.09 | -0.01 | buy |
| DIMENSIONAL FUND ADVISORS LP | 950,626 | 950,604 | -22 | 0.02 | 0.01 | -0.00 | sell |
| FEDERATED HERMES, INC. | 891,031 | 935,370 | +44,339 | 0.14 | 0.12 | -0.02 | buy |
| FIRST TRUST ADVISORS LP | 918,358 | 894,006 | -24,352 | 0.06 | 0.05 | -0.01 | sell |
| AMERIPRISE FINANCIAL INC | 891,199 | 856,545 | -34,654 | 0.02 | 0.01 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 1,596,760 | 834,969 | -761,791 | 0.10 | 0.04 | -0.05 | sell |
| PRUDENTIAL FINANCIAL INC | 127,661 | 770,414 | +642,753 | 0.01 | 0.06 | +0.05 | buy |
| GOLDMAN SACHS GROUP INC | 1,178,526 | 724,845 | -453,681 | 0.02 | 0.01 | -0.01 | sell |
| Swedbank AB | 632,935 | 657,193 | +24,258 | 0.06 | 0.33 | +0.26 | buy |
| BANK OF MONTREAL /CAN/ | 447,011 | 652,786 | +205,775 | 0.01 | 0.01 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 890,506 | 643,656 | -246,850 | 0.01 | 0.00 | -0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 285,687 | 638,555 | +352,868 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 300,004 | 629,793 | +329,789 | 0.15 | 0.28 | +0.13 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 663,893 | 625,450 | -38,443 | 0.03 | 0.02 | -0.01 | sell |
| ROYAL BANK OF CANADA | 682,972 | 593,520 | -89,452 | 0.01 | 0.01 | -0.00 | sell |
| Assenagon Asset Management S.A. | 634,623 | 578,421 | -56,202 | 0.12 | 0.09 | -0.03 | sell |
| Swiss National Bank | 595,600 | 570,500 | -25,100 | 0.03 | 0.02 | -0.00 | sell |
| WORLDQUANT MILLENNIUM ADVISORS LLC | 994,516 | 560,071 | -434,445 | 0.87 | 0.39 | -0.48 | sell |
| Grantham, Mayo, Van Otterloo & Co. LLC | 540,140 | 524,847 | -15,293 | 0.15 | 0.11 | -0.04 | sell |
| PANAGORA ASSET MANAGEMENT INC | 484,444 | 501,933 | +17,489 | 0.17 | 0.15 | -0.02 | buy |
| BARCLAYS PLC | 487,843 | 493,345 | +5,502 | 0.02 | 0.01 | -0.00 | buy |
| Squarepoint Ops LLC | 649,516 | 463,930 | -185,586 | 0.17 | 0.11 | -0.06 | sell |
| JPMORGAN CHASE & CO | 521,470 | 440,566 | -80,904 | 0.00 | 0.00 | -0.00 | sell |
| ARK Investment Management LLC | 531,625 | 438,686 | -92,939 | 0.20 | 0.17 | -0.02 | sell |
| CITIGROUP INC | 488,584 | 426,331 | -62,253 | 0.04 | 0.03 | -0.01 | sell |
| CANADA PENSION PLAN INVESTMENT BOARD | 462,639 | 420,366 | -42,273 | 0.04 | 0.03 | -0.01 | sell |
| Cubist Systematic Strategies, LLC | 286,896 | 419,241 | +132,345 | 0.22 | 0.27 | +0.05 | buy |
| UBS Group AG | 522,071 | 404,112 | -117,959 | 0.01 | 0.01 | -0.01 | sell |
| Allspring Global Investments Holdings, LLC | 760,360 | 402,030 | -358,330 | 0.08 | 0.04 | -0.04 | sell |
| Capital World Investors | 396,000 | 396,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MACKENZIE FINANCIAL CORP | 373,789 | 393,819 | +20,030 | 0.04 | 0.03 | -0.00 | buy |
| RHUMBLINE ADVISERS | 603,852 | 386,421 | -217,431 | 0.04 | 0.02 | -0.02 | sell |
| Point72 Asset Management, L.P. | 0 | 380,100 | +380,100 | 0.00 | 0.06 | +0.06 | buy |
| Bridgewater Associates, LP | 368,034 | 366,612 | -1,422 | 0.13 | 0.11 | -0.02 | sell |
| ASHFORD CAPITAL MANAGEMENT INC | 372,769 | 348,845 | -23,924 | 3.14 | 2.69 | -0.45 | sell |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 335,735 | 323,302 | -12,433 | 0.08 | 0.06 | -0.02 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 302,912 | 305,501 | +2,589 | 0.03 | 0.02 | -0.00 | buy |
| Hudson Bay Capital Management LP | 327,500 | 300,433 | -27,067 | 0.18 | 0.15 | -0.03 | sell |
| Applied Finance Capital Management, LLC | 0 | 298,357 | +298,357 | 0.00 | 1.20 | +1.20 | buy |
| CITADEL ADVISORS LLC | 331,562 | 297,250 | -34,312 | 0.02 | 0.02 | -0.00 | sell |
| Mitsubishi UFJ Trust & Banking Corp | 298,995 | 294,458 | -4,537 | 0.04 | 0.04 | -0.01 | sell |
| ALLIANCEBERNSTEIN L.P. | 306,398 | 292,831 | -13,567 | 0.01 | 0.01 | -0.00 | sell |
| MARSHALL WACE, LLP | 42,659 | 291,701 | +249,042 | 0.01 | 0.03 | +0.02 | buy |
| Trexquant Investment LP | 295,414 | 272,250 | -23,164 | 0.42 | 0.31 | -0.11 | sell |
| SECTOR GAMMA AS | 398,699 | 264,895 | -133,804 | 6.07 | 4.25 | -1.82 | sell |
| FRANKLIN RESOURCES INC | 53,757 | 258,650 | +204,893 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 253,638 | 253,352 | -286 | 0.01 | 0.01 | -0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 261,509 | 245,654 | -15,855 | 0.01 | 0.01 | -0.00 | sell |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 224,903 | 239,122 | +14,219 | 0.03 | 0.04 | +0.01 | buy |
| Korea Investment CORP | 236,784 | 238,080 | +1,296 | 0.04 | 0.03 | -0.00 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 367,687 | 234,574 | -133,113 | 0.03 | 0.02 | -0.01 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 304,258 | 228,217 | -76,041 | 0.03 | 0.02 | -0.02 | sell |
| Mitsubishi UFJ Asset Management Co., Ltd. | 175,739 | 224,119 | +48,380 | 0.02 | 0.02 | -0.00 | buy |
| Gotham Asset Management, LLC | 158,534 | 219,531 | +60,997 | 0.18 | 0.19 | +0.00 | buy |
| JANE STREET GROUP, LLC | 388,252 | 219,224 | -169,028 | 0.03 | 0.02 | -0.01 | sell |
| Ensign Peak Advisors, Inc | 194,371 | 216,615 | +22,244 | 0.02 | 0.02 | -0.00 | buy |
| Illinois Municipal Retirement Fund | 236,144 | 210,470 | -25,674 | 0.25 | 0.18 | -0.06 | sell |
| SEI INVESTMENTS CO | 204,927 | 205,116 | +189 | 0.02 | 0.02 | -0.00 | buy |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 199,910 | 203,649 | +3,739 | 0.03 | 0.02 | -0.00 | buy |