| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 30,743,663 | 30,743,991 | +328 | 18.84 | 17.78 | -1.06 | buy |
| VANGUARD GROUP INC | 19,951,623 | 19,911,434 | -40,189 | 0.03 | 0.03 | +0.00 | sell |
| BlackRock, Inc. | 17,894,297 | 18,327,923 | +433,626 | 0.03 | 0.03 | +0.00 | buy |
| DODGE & COX | 13,932,416 | 13,261,742 | -670,674 | 0.64 | 0.71 | +0.07 | sell |
| STATE STREET CORP | 9,676,796 | 9,656,403 | -20,393 | 0.03 | 0.03 | +0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 7,923,511 | 6,720,024 | -1,203,487 | 0.43 | 0.35 | -0.08 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 4,486,170 | 4,993,012 | +506,842 | 0.02 | 0.03 | +0.01 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 4,528,132 | 3,978,332 | -549,800 | 0.51 | 0.61 | +0.10 | sell |
| LSV ASSET MANAGEMENT | 3,986,097 | 3,933,758 | -52,339 | 0.75 | 0.85 | +0.10 | sell |
| Invesco Ltd. | 3,068,170 | 3,473,781 | +405,611 | 0.04 | 0.04 | +0.00 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 3,103,946 | 3,094,460 | -9,486 | 0.17 | 0.18 | +0.01 | sell |
| MORGAN STANLEY | 2,640,736 | 2,663,823 | +23,087 | 0.01 | 0.02 | +0.00 | buy |
| Robeco Institutional Asset Management B.V. | 2,319,388 | 2,480,793 | +161,405 | 0.28 | 0.35 | +0.06 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 1,761,171 | 2,288,874 | +527,703 | 0.51 | 0.72 | +0.22 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 1,743,794 | 2,284,317 | +540,523 | 0.59 | 0.87 | +0.28 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 2,241,208 | 1,844,752 | -396,456 | 0.33 | 0.30 | -0.03 | sell |
| DIMENSIONAL FUND ADVISORS LP | 1,596,129 | 1,788,190 | +192,061 | 0.03 | 0.04 | +0.01 | buy |
| NORTHERN TRUST CORP | 1,722,016 | 1,760,843 | +38,827 | 0.02 | 0.02 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,716,741 | 1,732,639 | +15,898 | 0.02 | 0.03 | +0.00 | buy |
| Pacer Advisors, Inc. | 1,248,642 | 1,703,271 | +454,629 | 0.27 | 0.25 | -0.02 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,503,585 | 1,574,718 | +71,133 | 0.03 | 0.03 | +0.01 | buy |
| Legal & General Group Plc | 1,678,969 | 1,469,147 | -209,822 | 0.03 | 0.03 | +0.00 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 1,264,485 | 1,453,664 | +189,179 | 0.06 | 0.08 | +0.02 | buy |
| Pictet Asset Management Holding SA | 826,284 | 1,315,666 | +489,382 | 0.07 | 0.13 | +0.06 | buy |
| GOLDMAN SACHS GROUP INC | 1,294,826 | 1,283,694 | -11,132 | 0.02 | 0.02 | +0.00 | sell |
| FIRST TRUST ADVISORS LP | 756,326 | 1,276,586 | +520,260 | 0.05 | 0.09 | +0.04 | buy |
| DEUTSCHE BANK AG\ | 1,156,816 | 1,273,170 | +116,354 | 0.03 | 0.04 | +0.01 | buy |
| FMR LLC | 1,272,056 | 1,246,439 | -25,617 | 0.01 | 0.01 | +0.00 | sell |
| NORGES BANK | 0 | 1,244,233 | +1,244,233 | 0.00 | 0.01 | +0.01 | buy |
| ROYAL BANK OF CANADA | 1,485,759 | 1,116,382 | -369,377 | 0.02 | 0.02 | -0.00 | sell |
| CAISSE DE DEPOT ET PLACEMENT DU QUEBEC | 1,498,013 | 1,111,193 | -386,820 | 0.23 | 0.19 | -0.04 | sell |
| Man Group plc | 1,933,547 | 1,099,329 | -834,218 | 0.32 | 0.21 | -0.11 | sell |
| ARMISTICE CAPITAL, LLC | 1,167,431 | 1,098,102 | -69,329 | 3.11 | 2.66 | -0.45 | sell |
| MARSHALL WACE, LLP | 16,040 | 1,072,491 | +1,056,451 | 0.00 | 0.10 | +0.10 | buy |
| BANK OF AMERICA CORP /DE/ | 1,328,835 | 1,003,440 | -325,395 | 0.01 | 0.01 | -0.00 | sell |
| Bank of New York Mellon Corp | 1,015,139 | 1,002,249 | -12,890 | 0.02 | 0.02 | +0.00 | sell |
| PANAGORA ASSET MANAGEMENT INC | 1,478,372 | 992,115 | -486,257 | 0.51 | 0.35 | -0.16 | sell |
| BNP Paribas Asset Management Holding S.A. | 531,507 | 978,112 | +446,605 | 0.12 | 0.11 | -0.01 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 781,349 | 965,846 | +184,497 | 0.01 | 0.01 | +0.00 | buy |
| SOUND SHORE MANAGEMENT INC /CT/ | 849,856 | 929,832 | +79,976 | 2.38 | 2.92 | +0.54 | buy |
| AMERIPRISE FINANCIAL INC | 584,763 | 865,150 | +280,387 | 0.01 | 0.02 | +0.01 | buy |
| CITIGROUP INC | 560,028 | 792,728 | +232,700 | 0.03 | 0.05 | +0.02 | buy |
| Amundi | 501,131 | 774,186 | +273,055 | 0.01 | 0.02 | +0.01 | buy |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 768,325 | 768,325 | 0 | 0.42 | 0.45 | +0.03 | hold |
| Skandinaviska Enskilda Banken AB (publ) | 571,234 | 754,116 | +182,882 | 0.19 | 0.30 | +0.10 | buy |
| Russell Investments Group, Ltd. | 808,584 | 743,307 | -65,277 | 0.08 | 0.08 | +0.00 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 21,084 | 739,378 | +718,294 | 0.00 | 0.01 | +0.01 | buy |
| RHUMBLINE ADVISERS | 692,526 | 684,283 | -8,243 | 0.05 | 0.05 | +0.01 | sell |
| UBS Group AG | 1,455,682 | 680,083 | -775,599 | 0.02 | 0.01 | -0.01 | sell |
| SEI INVESTMENTS CO | 492,670 | 663,446 | +170,776 | 0.04 | 0.06 | +0.02 | buy |
| AustralianSuper Pty Ltd | 213,241 | 640,733 | +427,492 | 0.09 | 0.29 | +0.21 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 695,826 | 638,694 | -57,132 | 0.04 | 0.04 | +0.00 | sell |
| Woodline Partners LP | 346,164 | 600,642 | +254,478 | 0.14 | 0.23 | +0.09 | buy |
| FEDERATED HERMES, INC. | 586,615 | 562,137 | -24,478 | 0.09 | 0.09 | +0.00 | sell |
| FRANKLIN RESOURCES INC | 524,528 | 550,096 | +25,568 | 0.01 | 0.01 | +0.00 | buy |
| WORLDQUANT MILLENNIUM ADVISORS LLC | 72,642 | 531,693 | +459,051 | 0.03 | 0.20 | +0.18 | buy |
| IEQ CAPITAL, LLC | 495,069 | 525,172 | +30,103 | 0.13 | 0.16 | +0.03 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 555,080 | 480,181 | -74,899 | 0.03 | 0.03 | -0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 444,193 | 473,383 | +29,190 | 0.02 | 0.02 | +0.00 | buy |
| Nuveen, LLC | 452,731 | 467,412 | +14,681 | 0.01 | 0.01 | +0.00 | buy |
| Candriam S.C.A. | 753,332 | 460,070 | -293,262 | 0.33 | 0.23 | -0.11 | sell |
| Swiss National Bank | 474,174 | 454,874 | -19,300 | 0.02 | 0.03 | +0.00 | sell |
| JPMORGAN CHASE & CO | 447,720 | 443,436 | -4,284 | 0.00 | 0.00 | +0.00 | sell |
| Sumitomo Mitsui Trust Group, Inc. | 456,736 | 438,439 | -18,297 | 0.02 | 0.03 | +0.00 | sell |
| Vinva Investment Management Ltd | 169,732 | 435,993 | +266,261 | 0.28 | 0.54 | +0.26 | buy |
| MACKENZIE FINANCIAL CORP | 453,139 | 410,362 | -42,777 | 0.05 | 0.05 | +0.00 | sell |
| Mitsubishi UFJ Trust & Banking Corp | 397,532 | 399,615 | +2,083 | 0.07 | 0.09 | +0.02 | buy |
| Andra AP-fonden | 460,600 | 396,300 | -64,300 | 0.50 | 0.48 | -0.02 | sell |
| BARCLAYS PLC | 488,131 | 391,819 | -96,312 | 0.02 | 0.02 | +0.00 | sell |
| Swedbank AB | 371,856 | 367,229 | -4,627 | 0.03 | 0.04 | +0.00 | sell |
| Gotham Asset Management, LLC | 234,428 | 352,695 | +118,267 | 0.09 | 0.13 | +0.04 | buy |
| Mitsubishi UFJ Asset Management Co., Ltd. | 314,183 | 346,679 | +32,496 | 0.02 | 0.02 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 324,392 | 341,382 | +16,990 | 0.02 | 0.02 | -0.00 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 387,605 | 336,114 | -51,491 | 0.01 | 0.01 | +0.00 | sell |
| Bridgewater Associates, LP | 131,284 | 328,590 | +197,306 | 0.04 | 0.12 | +0.07 | buy |
| NORDEA INVESTMENT MANAGEMENT AB | 30,930 | 322,223 | +291,293 | 0.00 | 0.03 | +0.03 | buy |
| Grantham, Mayo, Van Otterloo & Co. LLC | 248,843 | 296,345 | +47,502 | 0.06 | 0.07 | +0.02 | buy |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 355,840 | 294,740 | -61,100 | 0.23 | 0.22 | -0.01 | sell |
| WELLS FARGO & COMPANY/MN | 204,222 | 294,078 | +89,856 | 0.00 | 0.01 | +0.00 | buy |
| HSBC HOLDINGS PLC | 287,857 | 290,255 | +2,398 | 0.01 | 0.02 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 326,681 | 286,585 | -40,096 | 0.03 | 0.03 | +0.00 | sell |
| TODD ASSET MANAGEMENT LLC | 345,023 | 283,463 | -61,560 | 0.59 | 0.55 | -0.05 | sell |
| KBC Group NV | 425,094 | 267,394 | -157,700 | 0.09 | 0.06 | -0.03 | sell |
| Ensign Peak Advisors, Inc | 121,479 | 250,895 | +129,416 | 0.02 | 0.04 | +0.03 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 255,769 | 246,459 | -9,310 | 0.02 | 0.02 | +0.00 | sell |
| Illinois Municipal Retirement Fund | 222,839 | 232,708 | +9,869 | 0.24 | 0.29 | +0.05 | buy |
| LBP AM SA | 238,705 | 231,427 | -7,278 | 0.25 | 0.27 | +0.02 | sell |
| Cerity Partners LLC | 203,000 | 224,916 | +21,916 | 0.03 | 0.03 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 215,319 | 220,922 | +5,603 | 0.01 | 0.01 | +0.00 | buy |
| SECTOR GAMMA AS | 205,114 | 218,783 | +13,669 | 4.31 | 4.93 | +0.61 | buy |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 6,494 | 212,519 | +206,025 | 0.00 | 0.04 | +0.03 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 188,362 | 210,097 | +21,735 | 0.03 | 0.03 | +0.01 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 124,703 | 208,927 | +84,224 | 0.02 | 0.04 | +0.02 | buy |
| CWM, LLC | 196,472 | 205,824 | +9,352 | 0.05 | 0.06 | +0.00 | buy |
| APG Asset Management N.V. | 232,520 | 195,136 | -37,384 | 0.05 | 0.05 | -0.00 | sell |
| LAZARD ASSET MANAGEMENT LLC | 146,483 | 192,594 | +46,111 | 0.02 | 0.03 | +0.02 | buy |
| BANK OF MONTREAL /CAN/ | 161,803 | 190,559 | +28,756 | 0.01 | 0.01 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 203,382 | 189,710 | -13,672 | 0.01 | 0.01 | +0.00 | sell |
| KLP KAPITALFORVALTNING AS | 186,305 | 186,905 | +600 | 0.06 | 0.07 | +0.01 | buy |
| SG Americas Securities, LLC | 25,666 | 186,790 | +161,124 | 0.01 | 0.02 | +0.02 | buy |