| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| MILLENNIUM MANAGEMENT LLC | 790,105 | 3,812,874 | +3,022,769 | 0.01 | 0.03 | +0.02 | buy |
| UBS Group AG | 240,352 | 2,403,186 | +2,162,834 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 315,263 | 1,589,112 | +1,273,849 | 0.00 | 0.01 | +0.01 | buy |
| JUPITER ASSET MANAGEMENT LTD | 1,177,929 | 2,148,969 | +971,040 | 0.09 | 0.15 | +0.07 | buy |
| Parkman Healthcare Partners LLC | 216,881 | 1,000,562 | +783,681 | 0.22 | 0.89 | +0.67 | buy |
| TWO SIGMA ADVISERS, LP | 2,499,812 | 3,220,712 | +720,900 | 0.04 | 0.05 | +0.01 | buy |
| Legal & General Group Plc | 275,083 | 981,218 | +706,135 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 22,095,163 | 22,769,246 | +674,083 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 272,844 | 940,665 | +667,821 | 0.00 | 0.01 | +0.01 | buy |
| GOLDMAN SACHS GROUP INC | 1,291,230 | 1,931,934 | +640,704 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 1,665,732 | 2,297,674 | +631,942 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 474,376 | 1,065,583 | +591,207 | 0.00 | 0.00 | +0.00 | buy |
| Pictet Asset Management Holding SA | 26,442 | 612,324 | +585,882 | 0.00 | 0.01 | +0.01 | buy |
| BANK OF AMERICA CORP /DE/ | 899,838 | 1,435,657 | +535,819 | 0.00 | 0.00 | +0.00 | buy |
| Hudson Bay Capital Management LP | 0 | 498,679 | +498,679 | 0.00 | 0.02 | +0.02 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 194,797 | 670,361 | +475,564 | 0.00 | 0.01 | +0.01 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 1,579,960 | 2,033,783 | +453,823 | 0.04 | 0.06 | +0.01 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 633,864 | 1,042,424 | +408,560 | 0.02 | 0.03 | +0.01 | buy |
| Squarepoint Ops LLC | 359,881 | 764,898 | +405,017 | 0.01 | 0.01 | +0.01 | buy |
| Schonfeld Strategic Advisors LLC | 217,740 | 612,219 | +394,479 | 0.01 | 0.03 | +0.02 | buy |
| AQR CAPITAL MANAGEMENT LLC | 839,274 | 1,201,449 | +362,175 | 0.01 | 0.01 | +0.00 | buy |
| CITADEL ADVISORS LLC | 258,545 | 574,189 | +315,644 | 0.00 | 0.00 | +0.00 | buy |
| HUSSMAN STRATEGIC ADVISORS, INC. | 0 | 315,000 | +315,000 | 0.00 | 0.57 | +0.57 | buy |
| STATE STREET CORP | 7,498,967 | 7,813,404 | +314,437 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 1,774,214 | 2,045,535 | +271,321 | 0.03 | 0.03 | +0.00 | buy |
| PDT Partners, LLC | 522,290 | 778,729 | +256,439 | 0.35 | 0.41 | +0.07 | buy |
| ALGERT GLOBAL LLC | 725,305 | 960,057 | +234,752 | 0.13 | 0.18 | +0.05 | buy |
| Eversept Partners, LP | 1,980,312 | 2,172,436 | +192,124 | 1.54 | 1.84 | +0.31 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 225,700 | 396,862 | +171,162 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 89,954 | 232,363 | +142,409 | 0.00 | 0.01 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 4,823,735 | 4,960,637 | +136,902 | 0.00 | 0.00 | +0.00 | buy |
| ALKEON CAPITAL MANAGEMENT LLC | 7,093,822 | 7,214,021 | +120,199 | 0.31 | 0.32 | +0.01 | buy |
| GSA CAPITAL PARTNERS LLP | 164,484 | 278,552 | +114,068 | 0.09 | 0.19 | +0.10 | buy |
| WELLS FARGO & COMPANY/MN | 104,163 | 218,084 | +113,921 | 0.00 | 0.00 | +0.00 | buy |
| Caligan Partners LP | 2,995,932 | 3,107,669 | +111,737 | 5.71 | 4.86 | -0.84 | buy |
| Main Management ETF Advisors, LLC | 0 | 110,304 | +110,304 | 0.00 | 0.04 | +0.04 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 427,282 | 528,246 | +100,964 | 0.01 | 0.01 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 99,900 | +99,900 | 0.00 | 0.08 | +0.08 | buy |
| IEQ CAPITAL, LLC | 29,436 | 122,703 | +93,267 | 0.00 | 0.01 | +0.01 | buy |
| Engineers Gate Manager LP | 23,250 | 113,054 | +89,804 | 0.00 | 0.01 | +0.01 | buy |
| TWINBEECH CAPITAL LP | 0 | 83,470 | +83,470 | 0.00 | 0.01 | +0.01 | buy |
| CITIGROUP INC | 276,702 | 352,183 | +75,481 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 27,966 | 103,329 | +75,363 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 68,623 | 141,865 | +73,242 | 0.03 | 0.07 | +0.04 | buy |
| XTX Topco Ltd | 21,069 | 87,389 | +66,320 | 0.01 | 0.03 | +0.02 | buy |
| FRANKLIN RESOURCES INC | 262,382 | 324,395 | +62,013 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 60,933 | +60,933 | 0.00 | 0.01 | +0.01 | buy |
| Exome Asset Management LLC | 0 | 60,600 | +60,600 | 0.00 | 0.41 | +0.41 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 545,021 | 605,218 | +60,197 | 0.01 | 0.01 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 58,069 | +58,069 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 529,653 | 586,206 | +56,553 | 0.01 | 0.01 | +0.00 | buy |
| SEI INVESTMENTS CO | 57,190 | 109,467 | +52,277 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 401,111 | 448,466 | +47,355 | 0.00 | 0.00 | +0.00 | buy |
| Virtus Investment Advisers, LLC | 0 | 47,239 | +47,239 | 0.00 | 0.10 | +0.10 | buy |
| Gotham Asset Management, LLC | 0 | 44,064 | +44,064 | 0.00 | 0.00 | +0.00 | buy |
| EntryPoint Capital, LLC | 0 | 40,528 | +40,528 | 0.00 | 0.14 | +0.14 | buy |
| Graham Capital Management, L.P. | 97,257 | 136,103 | +38,846 | 0.02 | 0.03 | +0.01 | buy |
| Mach-1 Financial Group, LLC | 0 | 38,359 | +38,359 | 0.00 | 0.09 | +0.09 | buy |
| AlphaQuest LLC | 28,442 | 62,646 | +34,204 | 0.03 | 0.05 | +0.02 | buy |
| CWM, LLC | 20,094 | 53,750 | +33,656 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 33,149 | +33,149 | 0.00 | 0.01 | +0.01 | buy |
| LAZARD ASSET MANAGEMENT LLC | 161,516 | 194,553 | +33,037 | 0.00 | 0.00 | +0.00 | buy |
| MACKENZIE FINANCIAL CORP | 84,662 | 116,258 | +31,596 | 0.00 | 0.00 | +0.00 | buy |
| STRS OHIO | 8,300 | 37,800 | +29,500 | 0.00 | 0.00 | +0.00 | buy |
| Polymer Capital Management (US) LLC | 0 | 29,290 | +29,290 | 0.00 | 0.07 | +0.07 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 247,795 | 276,859 | +29,064 | 0.01 | 0.01 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 1,720,581 | 1,747,306 | +26,725 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 19,338 | 45,850 | +26,512 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 97,793 | 124,172 | +26,379 | 0.01 | 0.01 | +0.00 | buy |
| FIDUCIARY TRUST CO | 0 | 26,019 | +26,019 | 0.00 | 0.00 | +0.00 | buy |
| Magnetar Financial LLC | 0 | 25,420 | +25,420 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 11,992 | 36,410 | +24,418 | 0.00 | 0.00 | +0.00 | buy |
| Savant Capital, LLC | 10,585 | 32,420 | +21,835 | 0.00 | 0.00 | +0.00 | buy |
| Campbell & CO Investment Adviser LLC | 0 | 21,684 | +21,684 | 0.00 | 0.01 | +0.01 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 17,628 | 37,671 | +20,043 | 0.00 | 0.00 | +0.00 | buy |
| Knott David M Jr | 440,000 | 460,000 | +20,000 | 1.20 | 1.63 | +0.43 | buy |
| Pallas Capital Advisors LLC | 0 | 19,797 | +19,797 | 0.00 | 0.01 | +0.01 | buy |
| Rafferty Asset Management, LLC | 234,836 | 253,325 | +18,489 | 0.01 | 0.01 | +0.00 | buy |
| FEDERATED HERMES, INC. | 167,957 | 184,904 | +16,947 | 0.00 | 0.00 | +0.00 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0 | 16,704 | +16,704 | 0.00 | 0.00 | +0.00 | buy |
| OSAIC HOLDINGS, INC. | 28,169 | 44,145 | +15,976 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 54,446 | 69,860 | +15,414 | 0.00 | 0.00 | +0.00 | buy |
| Merit Financial Group, LLC | 0 | 13,360 | +13,360 | 0.00 | 0.00 | +0.00 | buy |
| SIH Partners, LLLP | 0 | 12,639 | +12,639 | 0.00 | 0.01 | +0.01 | buy |
| RHUMBLINE ADVISERS | 309,132 | 321,154 | +12,022 | 0.00 | 0.00 | +0.00 | buy |
| Allspring Global Investments Holdings, LLC | 0 | 10,574 | +10,574 | 0.00 | 0.00 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 0 | 10,282 | +10,282 | 0.00 | 0.00 | +0.00 | buy |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 47,100 | 56,704 | +9,604 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 126,797 | 135,314 | +8,517 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 13,258 | 21,644 | +8,386 | 0.00 | 0.00 | +0.00 | buy |
| New Age Alpha Advisors, LLC | 0 | 8,235 | +8,235 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 126,806 | 134,295 | +7,489 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 88,854 | 96,288 | +7,434 | 0.01 | 0.01 | +0.00 | buy |
| E Fund Management Co., Ltd. | 16,612 | 23,674 | +7,062 | 0.01 | 0.01 | +0.00 | buy |
| OXFORD ASSET MANAGEMENT LLP | 13,165 | 20,217 | +7,052 | 0.05 | 0.07 | +0.02 | buy |
| PROFUND ADVISORS LLC | 47,750 | 53,981 | +6,231 | 0.01 | 0.02 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 99,450 | 105,042 | +5,592 | 0.01 | 0.01 | -0.00 | buy |
| R Squared Ltd | 6,335 | 11,670 | +5,335 | 0.05 | 0.09 | +0.05 | buy |
| Headlands Technologies LLC | 0 | 4,219 | +4,219 | 0.00 | 0.00 | +0.00 | buy |
| CAPTRUST FINANCIAL ADVISORS | 16,498 | 20,578 | +4,080 | 0.00 | 0.00 | +0.00 | buy |