| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | 0 | 4,225,000 | +4,225,000 | 0.00 | 0.64 | +0.64 | buy |
| STATE STREET CORP | 10,740,198 | 14,623,269 | +3,883,071 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 1,300,557 | 3,571,955 | +2,271,398 | 0.01 | 0.01 | +0.01 | buy |
| EcoR1 Capital, LLC | 0 | 1,660,000 | +1,660,000 | 0.00 | 0.43 | +0.43 | buy |
| APIS CAPITAL ADVISORS, LLC | 0 | 1,200,100 | +1,200,100 | 0.00 | 1.19 | +1.19 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 850,797 | 1,757,487 | +906,690 | 0.01 | 0.02 | +0.01 | buy |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 0 | 707,140 | +707,140 | 0.00 | 0.01 | +0.01 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,205,450 | 1,882,234 | +676,784 | 0.01 | 0.01 | +0.01 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 1,234,168 | 1,861,046 | +626,878 | 0.02 | 0.04 | +0.01 | buy |
| MORGAN STANLEY | 3,850,451 | 4,443,922 | +593,471 | 0.00 | 0.00 | +0.00 | buy |
| FIRST TRUST ADVISORS LP | 0 | 587,186 | +587,186 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 501,891 | 1,089,059 | +587,168 | 0.00 | 0.00 | +0.00 | buy |
| Trexquant Investment LP | 0 | 446,930 | +446,930 | 0.00 | 0.02 | +0.02 | buy |
| DIMENSIONAL FUND ADVISORS LP | 4,016,682 | 4,443,603 | +426,921 | 0.00 | 0.01 | +0.00 | buy |
| SEI INVESTMENTS CO | 102,309 | 472,859 | +370,550 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 477,207 | 843,026 | +365,819 | 0.00 | 0.00 | +0.00 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 485,094 | 827,853 | +342,759 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 173,268 | 484,162 | +310,894 | 0.01 | 0.01 | +0.01 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 0 | 300,504 | +300,504 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 264,293 | +264,293 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 3,318,761 | 3,577,534 | +258,773 | 0.00 | 0.00 | +0.00 | buy |
| DELTEC ASSET MANAGEMENT LLC | 723,500 | 974,700 | +251,200 | 0.64 | 0.92 | +0.27 | buy |
| VANGUARD GROUP INC | 17,630,583 | 17,880,873 | +250,290 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 245,279 | +245,279 | 0.00 | 0.02 | +0.02 | buy |
| Rafferty Asset Management, LLC | 209,432 | 452,470 | +243,038 | 0.00 | 0.01 | +0.01 | buy |
| BlackRock, Inc. | 28,710,136 | 28,949,515 | +239,379 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 238,681 | +238,681 | 0.00 | 0.03 | +0.03 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,694,000 | 1,894,000 | +200,000 | 0.01 | 0.02 | +0.00 | buy |
| BARCLAYS PLC | 846,056 | 1,025,437 | +179,381 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 375,228 | 548,257 | +173,029 | 0.00 | 0.00 | +0.00 | buy |
| Aquatic Capital Management LLC | 55,040 | 222,163 | +167,123 | 0.01 | 0.04 | +0.03 | buy |
| Russell Investments Group, Ltd. | 433,846 | 578,402 | +144,556 | 0.00 | 0.00 | +0.00 | buy |
| Calamos Advisors LLC | 230,911 | 370,718 | +139,807 | 0.01 | 0.01 | +0.00 | buy |
| AXIOM INVESTORS LLC /DE | 899,400 | 1,037,704 | +138,304 | 0.04 | 0.05 | +0.02 | buy |
| Brevan Howard Capital Management LP | 0 | 122,610 | +122,610 | 0.00 | 0.01 | +0.01 | buy |
| Walleye Capital LLC | 0 | 121,148 | +121,148 | 0.00 | 0.00 | +0.00 | buy |
| PROFUND ADVISORS LLC | 48,778 | 169,001 | +120,223 | 0.01 | 0.03 | +0.02 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 116,975 | +116,975 | 0.00 | 0.00 | +0.00 | buy |
| KING LUTHER CAPITAL MANAGEMENT CORP | 0 | 102,995 | +102,995 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 232,708 | 333,829 | +101,121 | 0.00 | 0.00 | +0.00 | buy |
| BIT Capital GmbH | 0 | 101,000 | +101,000 | 0.00 | 0.02 | +0.02 | buy |
| DIADEMA PARTNERS LP | 212,475 | 302,000 | +89,525 | 0.79 | 1.02 | +0.22 | buy |
| State of Wyoming | 0 | 88,311 | +88,311 | 0.00 | 0.05 | +0.05 | buy |
| 180 WEALTH ADVISORS, LLC | 2,872,286 | 2,958,944 | +86,658 | 1.88 | 1.91 | +0.03 | buy |
| DARK FOREST CAPITAL MANAGEMENT LP | 13,127 | 98,402 | +85,275 | 0.00 | 0.03 | +0.02 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 112,516 | 194,978 | +82,462 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 98,651 | 178,494 | +79,843 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 73,206 | +73,206 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 79,935 | 143,592 | +63,657 | 0.00 | 0.00 | -0.00 | buy |
| Headlands Technologies LLC | 0 | 55,890 | +55,890 | 0.00 | 0.03 | +0.03 | buy |
| HSBC HOLDINGS PLC | 29,575 | 71,068 | +41,493 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 267,940 | 307,158 | +39,218 | 0.00 | 0.00 | +0.00 | buy |
| Magnetar Financial LLC | 0 | 37,398 | +37,398 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 0 | 37,260 | +37,260 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 38,141 | 73,345 | +35,204 | 0.00 | 0.00 | +0.00 | buy |
| Bayesian Capital Management, LP | 0 | 35,200 | +35,200 | 0.00 | 0.46 | +0.46 | buy |
| Jefferies Financial Group Inc. | 33,000 | 66,333 | +33,333 | 0.00 | 0.00 | +0.00 | buy |
| Quantinno Capital Management LP | 0 | 33,322 | +33,322 | 0.00 | 0.00 | +0.00 | buy |
| Voleon Capital Management LP | 237,242 | 269,796 | +32,554 | 0.03 | 0.03 | +0.00 | buy |
| Persistent Asset Partners Ltd | 49,262 | 81,463 | +32,201 | 0.19 | 0.22 | +0.03 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 32,108 | +32,108 | 0.00 | 0.00 | +0.00 | buy |
| 1492 Capital Management LLC | 504,244 | 535,270 | +31,026 | 1.10 | 1.16 | +0.07 | buy |
| Polymer Capital Management (US) LLC | 0 | 29,545 | +29,545 | 0.00 | 0.02 | +0.02 | buy |
| GROUP ONE TRADING LLC | 28,067 | 55,099 | +27,032 | 0.00 | 0.01 | +0.00 | buy |
| Graham Capital Management, L.P. | 0 | 26,548 | +26,548 | 0.00 | 0.01 | +0.01 | buy |
| Concurrent Investment Advisors, LLC | 0 | 26,000 | +26,000 | 0.00 | 0.00 | +0.00 | buy |
| Abel Hall, LLC | 0 | 24,269 | +24,269 | 0.00 | 0.03 | +0.03 | buy |
| UNITED CAPITAL FINANCIAL ADVISORS, LLC | 0 | 23,631 | +23,631 | 0.00 | 0.00 | +0.00 | buy |
| Gotham Asset Management, LLC | 0 | 21,681 | +21,681 | 0.00 | 0.00 | +0.00 | buy |
| WINTON GROUP Ltd | 0 | 20,817 | +20,817 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 187,720 | 204,121 | +16,401 | 0.00 | 0.00 | +0.00 | buy |
| Abacus Wealth Partners, LLC | 0 | 16,277 | +16,277 | 0.00 | 0.01 | +0.01 | buy |
| NATIONS FINANCIAL GROUP INC, /IA/ /ADV | 0 | 15,451 | +15,451 | 0.00 | 0.00 | +0.00 | buy |
| Swiss National Bank | 559,900 | 574,700 | +14,800 | 0.00 | 0.00 | +0.00 | buy |
| Freestone Grove Partners LP | 0 | 14,137 | +14,137 | 0.00 | 0.00 | +0.00 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 0 | 13,120 | +13,120 | 0.00 | 0.00 | +0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 0 | 12,411 | +12,411 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKET INC. | 18,646 | 30,133 | +11,487 | 0.00 | 0.00 | +0.00 | buy |
| Lido Advisors, LLC | 0 | 11,185 | +11,185 | 0.00 | 0.00 | +0.00 | buy |
| STIFEL FINANCIAL CORP | 43,625 | 54,740 | +11,115 | 0.00 | 0.00 | +0.00 | buy |
| Laurel Wealth Advisors LLC | 0 | 10,627 | +10,627 | 0.00 | 0.01 | +0.01 | buy |
| BURKETT FINANCIAL SERVICES, LLC | 0 | 10,460 | +10,460 | 0.00 | 0.02 | +0.02 | buy |
| HUNTINGTON NATIONAL BANK | 2,000 | 10,400 | +8,400 | 0.00 | 0.00 | +0.00 | buy |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | 0 | 8,000 | +8,000 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 13,966 | 21,679 | +7,713 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 17,055 | 23,962 | +6,907 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 62,702 | 69,130 | +6,428 | 0.00 | 0.00 | -0.00 | buy |
| HUNTER ASSOCIATES INVESTMENT MANAGEMENT LLC | 63,700 | 68,700 | +5,000 | 0.05 | 0.05 | +0.00 | buy |
| BNP Paribas Asset Management Holding S.A. | 0 | 4,340 | +4,340 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 202,412 | 206,612 | +4,200 | 0.00 | 0.00 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 102,118 | 105,945 | +3,827 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 11,862 | 14,922 | +3,060 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 206,702 | 209,479 | +2,777 | 0.00 | 0.00 | -0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 54,871 | 57,385 | +2,514 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 36,791 | 39,234 | +2,443 | 0.00 | 0.00 | -0.00 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 31,001 | 33,405 | +2,404 | 0.00 | 0.00 | +0.00 | buy |
| Aaron Wealth Advisors LLC | 198,408 | 200,763 | +2,355 | 0.06 | 0.06 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 113,137 | 115,191 | +2,054 | 0.01 | 0.02 | +0.00 | buy |
| MACKENZIE FINANCIAL CORP | 20,719 | 22,531 | +1,812 | 0.00 | 0.00 | +0.00 | buy |
| OSAIC HOLDINGS, INC. | 58,406 | 60,126 | +1,720 | 0.00 | 0.00 | +0.00 | buy |