| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 9,930,926 | 10,056,446 | +125,520 | 0.03 | 0.03 | -0.00 | buy |
| STATE STREET CORP | 3,989,961 | 4,608,357 | +618,396 | 0.02 | 0.03 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 2,251,646 | 2,468,146 | +216,500 | 0.49 | 0.58 | +0.09 | buy |
| JPMORGAN CHASE & CO | 2,295,108 | 2,362,735 | +67,627 | 0.03 | 0.03 | -0.00 | buy |
| Bellevue Group AG | 2,055,874 | 1,898,640 | -157,234 | 4.32 | 4.25 | -0.08 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 1,713,714 | 1,819,622 | +105,908 | 0.02 | 0.02 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,820,796 | 1,798,848 | -21,948 | 0.03 | 0.03 | -0.00 | sell |
| MORGAN STANLEY | 2,065,636 | 1,544,869 | -520,767 | 0.02 | 0.02 | -0.01 | sell |
| DODGE & COX | 1,265,244 | 1,280,820 | +15,576 | 0.10 | 0.11 | +0.00 | buy |
| Invesco Ltd. | 1,136,942 | 1,258,104 | +121,162 | 0.03 | 0.04 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 994,611 | 1,223,055 | +228,444 | 0.23 | 0.26 | +0.02 | buy |
| GOLDMAN SACHS GROUP INC | 775,727 | 1,132,589 | +356,862 | 0.02 | 0.03 | +0.01 | buy |
| DSM CAPITAL PARTNERS LLC | 1,136,002 | 997,784 | -138,218 | 2.14 | 1.99 | -0.15 | sell |
| BROWN ADVISORY INC | 1,088,333 | 995,214 | -93,119 | 0.20 | 0.18 | -0.02 | sell |
| ARMISTICE CAPITAL, LLC | 1,023,739 | 978,488 | -45,251 | 3.76 | 3.52 | -0.24 | sell |
| JANUS HENDERSON GROUP PLC | 1,378,513 | 971,203 | -407,310 | 0.10 | 0.07 | -0.03 | sell |
| Rock Springs Capital Management LP | 1,054,900 | 940,000 | -114,900 | 3.70 | 3.91 | +0.21 | sell |
| Bank of New York Mellon Corp | 921,335 | 934,404 | +13,069 | 0.02 | 0.02 | -0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 599,424 | 912,064 | +312,640 | 0.03 | 0.04 | +0.01 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 1,003,750 | 899,493 | -104,257 | 0.02 | 0.02 | -0.00 | sell |
| Pictet Asset Management Holding SA | 1,081,449 | 871,324 | -210,125 | 0.16 | 0.14 | -0.02 | sell |
| NORTHERN TRUST CORP | 715,068 | 810,620 | +95,552 | 0.02 | 0.02 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 793,825 | 808,450 | +14,625 | 0.03 | 0.03 | -0.00 | buy |
| BNP Paribas Asset Management Holding S.A. | 790,193 | 782,870 | -7,323 | 0.29 | 0.28 | -0.01 | sell |
| BRAIDWELL LP | 730,209 | 759,009 | +28,800 | 3.25 | 3.28 | +0.03 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 725,178 | 752,501 | +27,323 | 0.02 | 0.02 | -0.00 | buy |
| CITADEL ADVISORS LLC | 841,318 | 740,939 | -100,379 | 0.11 | 0.10 | -0.01 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 712,798 | 721,087 | +8,289 | 0.44 | 0.41 | -0.03 | buy |
| Allspring Global Investments Holdings, LLC | 506,666 | 710,600 | +203,934 | 0.11 | 0.16 | +0.05 | buy |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 691,004 | 691,004 | 0 | 1.66 | 1.58 | -0.08 | hold |
| CAISSE DE DEPOT ET PLACEMENT DU QUEBEC | 151,683 | 656,118 | +504,435 | 0.05 | 0.22 | +0.17 | buy |
| PERCEPTIVE ADVISORS LLC | 804,409 | 649,909 | -154,500 | 1.96 | 2.16 | +0.20 | sell |
| ALLIANCEBERNSTEIN L.P. | 160,223 | 621,865 | +461,642 | 0.01 | 0.03 | +0.02 | buy |
| BANK OF AMERICA CORP /DE/ | 566,713 | 618,931 | +52,218 | 0.01 | 0.01 | +0.00 | buy |
| Polar Capital Holdings Plc | 775,556 | 610,552 | -165,004 | 0.56 | 0.50 | -0.07 | sell |
| Qube Research & Technologies Ltd | 251,831 | 601,720 | +349,889 | 0.06 | 0.15 | +0.09 | buy |
| GW&K Investment Management, LLC | 527,874 | 546,068 | +18,194 | 0.64 | 0.69 | +0.05 | buy |
| 1832 Asset Management L.P. | 36,800 | 541,200 | +504,400 | 0.01 | 0.13 | +0.13 | buy |
| Fiera Capital Corp | 511,542 | 527,902 | +16,360 | 0.21 | 0.23 | +0.02 | buy |
| IEQ CAPITAL, LLC | 506,113 | 506,086 | -27 | 1.00 | 0.94 | -0.07 | sell |
| JENNISON ASSOCIATES LLC | 345,446 | 499,323 | +153,877 | 0.03 | 0.04 | +0.01 | buy |
| Avidity Partners Management LP | 536,500 | 491,000 | -45,500 | 2.63 | 2.87 | +0.24 | sell |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 580,617 | 485,020 | -95,597 | 0.06 | 0.05 | -0.01 | sell |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 503,193 | 484,777 | -18,416 | 0.36 | 0.33 | -0.04 | sell |
| DIMENSIONAL FUND ADVISORS LP | 325,022 | 472,929 | +147,907 | 0.01 | 0.02 | +0.00 | buy |
| Candriam S.C.A. | 315,684 | 465,467 | +149,783 | 0.28 | 0.39 | +0.11 | buy |
| NORGES BANK | 425,216 | 449,565 | +24,349 | 0.01 | 0.01 | -0.00 | buy |
| ORBIMED ADVISORS LLC | 423,100 | 448,200 | +25,100 | 1.07 | 1.23 | +0.16 | buy |
| FIRST TRUST ADVISORS LP | 526,582 | 433,537 | -93,045 | 0.07 | 0.06 | -0.01 | sell |
| DEUTSCHE BANK AG\ | 359,856 | 433,107 | +73,251 | 0.02 | 0.03 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 431,982 | 430,609 | -1,373 | 0.07 | 0.06 | -0.01 | sell |
| AMERIPRISE FINANCIAL INC | 405,347 | 413,172 | +7,825 | 0.02 | 0.02 | +0.00 | buy |
| Sarissa Capital Management LP | 346,426 | 410,483 | +64,057 | 8.36 | 9.54 | +1.18 | buy |
| PRIMECAP MANAGEMENT CO/CA/ | 399,380 | 409,290 | +9,910 | 0.04 | 0.04 | -0.00 | buy |
| Legal & General Group Plc | 402,616 | 402,499 | -117 | 0.02 | 0.02 | -0.00 | sell |
| Amundi | 361,672 | 391,313 | +29,641 | 0.02 | 0.02 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 418,675 | 373,762 | -44,913 | 0.03 | 0.03 | -0.00 | sell |
| FMR LLC | 232,519 | 341,829 | +109,310 | 0.00 | 0.00 | +0.00 | buy |
| Clearbridge Investments, LLC | 340,802 | 340,802 | 0 | 0.04 | 0.04 | +0.00 | hold |
| Robeco Institutional Asset Management B.V. | 310,225 | 333,981 | +23,756 | 0.09 | 0.10 | +0.01 | buy |
| RHUMBLINE ADVISERS | 322,107 | 324,288 | +2,181 | 0.04 | 0.04 | -0.00 | buy |
| UBS Group AG | 235,626 | 316,927 | +81,301 | 0.01 | 0.01 | +0.00 | buy |
| JUPITER ASSET MANAGEMENT LTD | 218,466 | 307,100 | +88,634 | 0.29 | 0.40 | +0.11 | buy |
| Swiss National Bank | 294,200 | 294,600 | +400 | 0.03 | 0.03 | -0.00 | buy |
| Russell Investments Group, Ltd. | 349,317 | 288,761 | -60,556 | 0.08 | 0.06 | -0.01 | sell |
| AXA S.A. | 243,689 | 284,022 | +40,333 | 0.10 | 0.12 | +0.02 | buy |
| Ensign Peak Advisors, Inc | 154,711 | 272,613 | +117,902 | 0.04 | 0.07 | +0.03 | buy |
| MACQUARIE GROUP LTD | 276,010 | 270,977 | -5,033 | 0.04 | 0.04 | -0.00 | sell |
| APG Asset Management N.V. | 377,118 | 257,315 | -119,803 | 0.08 | 0.06 | -0.03 | sell |
| Assenagon Asset Management S.A. | 337,737 | 249,424 | -88,313 | 0.12 | 0.09 | -0.04 | sell |
| Hood River Capital Management LLC | 227,998 | 243,897 | +15,899 | 0.70 | 0.70 | -0.01 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 252,565 | 243,443 | -9,122 | 0.02 | 0.02 | +0.00 | sell |
| WELLS FARGO & COMPANY/MN | 221,814 | 234,969 | +13,155 | 0.01 | 0.01 | +0.00 | buy |
| Man Group plc | 289,761 | 233,225 | -56,536 | 0.11 | 0.08 | -0.02 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 206,368 | 208,407 | +2,039 | 0.04 | 0.04 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 199,397 | 202,793 | +3,396 | 0.01 | 0.01 | -0.00 | buy |
| Iron Triangle Partners LP | 220,000 | 200,000 | -20,000 | 3.14 | 2.89 | -0.25 | sell |
| AMERICAN CENTURY COMPANIES INC | 227,019 | 198,536 | -28,483 | 0.02 | 0.02 | -0.00 | sell |
| SOROS FUND MANAGEMENT LLC | 159,776 | 194,776 | +35,000 | 0.51 | 0.60 | +0.09 | buy |
| PRUDENTIAL FINANCIAL INC | 116,118 | 194,254 | +78,136 | 0.02 | 0.04 | +0.02 | buy |
| MILLENNIUM MANAGEMENT LLC | 455,220 | 187,483 | -267,737 | 0.05 | 0.02 | -0.03 | sell |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 150,127 | 185,384 | +35,257 | 0.02 | 0.03 | +0.00 | buy |
| Holocene Advisors, LP | 0 | 185,344 | +185,344 | 0.00 | 0.11 | +0.11 | buy |
| ROYAL BANK OF CANADA | 162,534 | 167,427 | +4,893 | 0.01 | 0.01 | +0.00 | buy |
| BARCLAYS PLC | 257,239 | 162,389 | -94,850 | 0.02 | 0.01 | -0.01 | sell |
| Andra AP-fonden | 74,400 | 161,300 | +86,900 | 0.18 | 0.37 | +0.19 | buy |
| Aberdeen Group plc | 83,212 | 161,147 | +77,935 | 0.02 | 0.04 | +0.02 | buy |
| LOOMIS SAYLES & CO L P | 254,933 | 160,270 | -94,663 | 0.05 | 0.03 | -0.02 | sell |
| WORLDQUANT MILLENNIUM ADVISORS LLC | 69,461 | 158,485 | +89,024 | 0.12 | 0.20 | +0.08 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 151,873 | 155,985 | +4,112 | 0.01 | 0.01 | +0.00 | buy |
| COMERICA BANK | 135,646 | 152,824 | +17,178 | 0.08 | 0.09 | +0.01 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 148,983 | 151,481 | +2,498 | 0.02 | 0.02 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 143,434 | 140,267 | -3,167 | 0.02 | 0.02 | -0.00 | sell |
| BANCO BILBAO VIZCAYA ARGENTARIA, S.A. | 138,755 | 138,755 | 0 | 0.22 | 0.20 | -0.02 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 144,405 | 137,805 | -6,600 | 0.03 | 0.02 | -0.00 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 135,867 | 137,543 | +1,676 | 0.02 | 0.02 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 157,780 | 135,282 | -22,498 | 0.05 | 0.04 | -0.01 | sell |
| SEI INVESTMENTS CO | 86,669 | 128,016 | +41,347 | 0.02 | 0.02 | +0.01 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 124,327 | 125,401 | +1,074 | 0.02 | 0.02 | +0.00 | buy |
| Mitsubishi UFJ Trust & Banking Corp | 112,718 | 124,909 | +12,191 | 0.04 | 0.04 | +0.01 | buy |